A Beautiful Bind: Phage Display and the Search for Cell-Selective Peptides [PDF]
VirusesPhage display has advanced the discovery of peptides that selectively bind to a wide variety of cell surface molecules, offering new modalities to modulate disease-related protein–protein interactions (PPIs).
Babak Bakhshinejad, Saeedeh Ghiasvand
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Phage display: Binding confirmation
BioTechniques, 2010 This month's question from the Molecular Biology Forums (online at molecularbiology.forums.biotechniques.com) comes from the “Protein Methods” section. Entries have been edited for concision and clarity.
Kristie Nybo
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On the origin of non-specific binders isolated in the selection of phage display peptide libraries [PDF]
Frontiers in MicrobiologyOver the recent decades, phage display has been used successfully to identify a variety of peptides with diagnostic and therapeutic applications. Despite the significant role of this technology in the pharmaceutical industry, the affinity selection of ...
Babak Bakhshinejad +3 more
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Using NGS to Uncover the Corruption of a Peptide Phage Display Selection [PDF]
Current Issues in Molecular BiologyPhage display has been widely used to identify peptides binding to a variety of biological targets. In the current work, we planned to select novel peptides targeting CD4 through screening of a commercial phage display library (New England Biolabs Ph.D ...
Danna Kamstrup Sell +7 more
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Monoclonal Antibody Development for Cancer Treatment Using the Phage Display Library Platform [PDF]
BiologicsThirty-four years ago, the groundbreaking work of John McCafferty and Sir Gregory Winter in developing phage display technology revolutionized the discovery of human antibodies, paving the way for diverse applications.
Tiantian Zhang, Zhe Wang
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Development of an Anti-Zearalenone Nanobody Phage Display Library and Preparation of Specific Nanobodies [PDF]
Current Issues in Molecular BiologyZearalenone (ZEN), a toxic estrogenic mycotoxin in cereals, threatens human and animal health through reproductive, immune, and cytotoxic effects, necessitating sensitive detection methods.
Ying Zeng +9 more
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NGS and the design of an optimized phage display workflow for peptide discovery [PDF]
Amino AcidsPhage display is a powerful technology that has demonstrated great potential in identifying peptides with high binding affinity and specificity toward a broad spectrum of biological targets. The undesired enrichment of nonspecific binders remains a major
Babak Bakhshinejad, Andreas Kjaer
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Phage display technology in ecotoxicology: phage display derived unique peptide for copper identification in aquatic samples [PDF]
Microbial Cell FactoriesBackground Ecotoxicology is essential for the evaluation and comprehension of the effects of emergency pollutants (EP) such as heavy metal ions on the natural environment.
Marta Sosnowska +3 more
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A comparative analysis of sequence composition in different lots of a phage display peptide library during amplification [PDF]
Virology JournalBackground To develop efficient selection strategies and improve the discovery of promising ligands, it is highly desirable to analyze the sequence composition of naïve phage display libraries and monitor the evolution of their peptide content during ...
Anders Wilgaard Sinkjaer +5 more
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Phage Display Revealed the Complex Structure of the Epitope of the Monoclonal Antibody 10H10. [PDF]
Int J Mol SciShanshin DV +13 more
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