From Protease to Decarboxylase: The MOLECULAR METAMORPHOSIS OF PHOSPHATIDYLSERINE DECARBOXYLASE [PDF]
Journal of Biological Chemistry, 2015 Background: Phosphatidylserine decarboxylase (PSD) undergoes an autoendoproteolytic cleavage but the mechanism has not been defined.<p></p> Results: PSD proenzyme processing occurs by a canonical serine protease mechanism catalyzed by a ...
Choukri Ben Mamoun +2 more
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New sensitive assay for phosphatidylserine decarboxylase based on the detection of CO2 from nonradiolabeled phosphatidylserine [PDF]
Journal of Lipid Research, 1973 A new rapid assay for phosphatidylserine decarboxylase, which is sensitive in the nanomolar range, is described. Synthesis of radiolabeled phosphatidylserine for use as a substrate is not required, since the assay, unlike previous ones, is based on the ...
Thomas G. Warner, Edward A. Dennis
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Phosphatidylserine synthase 2 and phosphatidylserine decarboxylase are essential for aminophospholipid synthesis in Trypanosoma brucei. [PDF]
Mol Microbiol, 2017 The work was supported by Swiss National Science Foundation grant 149353 to PB, Wellcome Trust grants 067441 and 093228 and European Community’s Seventh Framework Programme under grant agreement No.
Farine L +6 more
europepmc +10 more sources
A Novel Fluorescence Assay for Measuring Phosphatidylserine Decarboxylase Catalysis [PDF]
Journal of Biological Chemistry, 2018 Phosphatidylserine decarboxylases (PSDs) are central enzymes in phospholipid metabolism that produce phosphatidylethanolamine (PE) in bacteria, protists, plants, and animals. We developed a fluorescence-based assay for selectively monitoring production of PE in reactions using a maltose-binding protein fusion with Plasmodium knowlesi PSD (MBP-His6 ...
Choukri Ben Mamoun +2 more
exaly +5 more sources
Enzymatic synthesis and decarboxylation of phosphatidylserine in Tetrahymena pyriformis [PDF]
Journal of Lipid Research, 1970 Cell-free extracts of the protozoan Tetrahymena pyriformis have been found to catalyze the following reactions: Phosphatidylethanolamine+L-Serine⇌Phosphatidylserine+EthanolaminePhosphatidylserine→Phosphatidylethanolamine+CO2Net:L-Serine→Ethanolamine ...
EDWARD A. DENNIS, EUGENE P. KENNEDY
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Phosphatidylserine decarboxylase from Clostridium butyricum.
Journal of Lipid Research, 1985 Phosphatidylserine decarboxylase activity has been characterized in membrane preparations from Clostridium butyricum ATCC 19398. A particulate fraction was shown to catalyze the formation of phosphatidylethanolamine and plasmenylethanolamine when ...
J N Verma, H Goldfine
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Phosphatidylserine Decarboxylase in Plants
, 2003 1 Titelblatt, Widmung und Inhaltsverzeichnis 2 Einleitung 2.1 Pflanzliche Lipide 5 2.2 Synthese und Funktion von Phosphatidylserin und Phosphatidylethanolamin 5 2.3 Pyruvoyl-abhängige Decarboxylasen 8 2.4 Phosphatidylserin Decarboxylase 13 2 ...
Orlow, Annine Melanie von
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SLMO transfers phosphatidylserine between the outer and inner mitochondrial membrane in Drosophila.
PLoS BiologyPhospholipids are critical building blocks of mitochondria, and proper mitochondrial function and architecture rely on phospholipids that are primarily transported from the endoplasmic reticulum (ER).
Siwen Zhao +3 more
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Journal of Fungi, 2018 The phospholipids phosphatidylserine (PS) and phosphatidylethanolamine (PE) play important roles in the virulence of Candida albicans and loss of PS synthesis or synthesis of PE from PS (PS decarboxylase) severely compromises virulence in C.
Chelsi D. Cassilly, Todd B. Reynolds
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Implications of mitochondrial phosphatidylethanolamine in neuronal health and neurodegeneration [PDF]
Neural Regeneration ResearchPhosphatidylethanolamine is a major phospholipid class abundant in the brain, particularly in the inner leaflet of the plasma and mitochondrial membranes. Although it is primarily synthesized from phosphatidylserine via decarboxylation in mitochondria or
Yantao Zuo, Niharika Amireddy, Qian Cai
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