Results 101 to 110 of about 47,089 (385)

Base-catalyzed reactions of environmentally relevant N-chloro-piperidines. A quantum-chemical study [PDF]

open access: yes, 2011
Electronic structure methods have been applied to calculate the gas and aqueous phase reaction energies for base-induced rearrangements of N-chloropiperidine, N-chloro-3-(hydroxymethyl)piperidine, and N-chloro-4-4-fluorophenyl)-3-(hydroxymethyl ...
Sakic, Davor   +2 more
core   +1 more source

Harnessing the Electrophilicity of Keteniminium Ions: A Simple and Straightforward Entry to Tetrahydropyridines and Piperidines from Ynamides

open access: yesAngewandte Chemie, 2016
An efficient, modular and straightforward entry to tetrahydropyridines and piperidines is reported. This reaction is based on a formal intramolecular hydroalkylation of readily available, properly substituted ynamides which, upon simple activation under ...
Morgan Lecomte, G. Evano
semanticscholar   +1 more source

N‐Containing Carbon Materials in Metal‐Free and Non‐Noble Metal Liquid Phase Heterogenous Catalysis

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
Over 100 examples of non‐noble metal supported on N‐containing and metal‐free N‐containing carbon catalysts are discussed. Particular emphasis is put on how different N‐functionalities influence catalyst performance and stability. Preparation procedures are also examined, with a strong focus on how the heat treatment temperature influences N ...
Fulvio Varamo, Anna Katharina Beine
wiley   +1 more source

A Most Unusual Zeolite Templating: Cage to Cage Connection of One Guest Molecule [PDF]

open access: yes, 2010
An unusual case of a diquaternary ammonium dication, with large bulky end groups built from the tropane moiety and connected by a C4 methylene chain, is found to reside in zeolite SSZ-35 (STF).
Burton, Allen W.   +6 more
core   +1 more source

Enantioselective Synthesis of Tetrahydropyridines/Piperidines via Stepwise [4 + 2]/[2 + 2] Cyclizations.

open access: yesOrganic Letters, 2017
A phosphine-catalyzed novel enantioselective [4 + 2]-annulation reaction between allene ketones and 1-azadienes has been developed, and tetrahydropyridines were obtained in good yields and with excellent enantioselectivities.
Zhen Wang   +6 more
semanticscholar   +1 more source

A Serum‐Stable Antimicrobial Peptide‐Based Delivery Platform for Selective Treatment of Nontargetable and Chemoresistant Tumors

open access: yesAdvanced Science, EarlyView.
A modular antimicrobial‐peptide‐based therapeutic system integrating membrane‐targeted selectivity, a conformation‐driven polyethylene glycolylated blocker, and serum‐stabilizing N‐cap is developed. The optimized conjugate 270 shows potent, rapid killing of the desired tumor cells, high serum stability, low off‐target toxicity, and broad applicability,
Tianxing Liu   +12 more
wiley   +1 more source

Cupin‐Type Dimethylsulfoniopropionate Lyase from Pelagibacter ubique (DddKPu) Catalyzes Aza‐Michael Addition of Primary and Secondary Amines to Acrylic Acid

open access: yesAngewandte Chemie, EarlyView.
A dimethylsulfoniopropionate lyase (DddK) was identified as an efficient aza‐Michaelase for the addition of amines to acrylate. Screening 74 amines with wild‐type DddK and its W26G variant yielded N‐substituted and N,N‐disubstituted β‐amino acids in 30%–93% isolated yield.
Diletta Arceri   +5 more
wiley   +2 more sources

Stereoselective, nitro-Mannich/lactamisation cascades for the direct synthesis of heavily decorated 5-nitropiperidin-2-ones and related heterocycles

open access: yesBeilstein Journal of Organic Chemistry, 2012
A versatile nitro-Mannich/lactamisation cascade for the direct stereoselective synthesis of heavily decorated 5-nitropiperidin-2-ones and related heterocycles has been developed. A highly enantioenriched substituted 5-nitropiperidin-2-one was synthesised
Pavol Jakubec   +4 more
doaj   +1 more source

Experimental study of local anesthetic and antiarrhythmic activities of fluorinated ethynylpiperidine derivatives [PDF]

open access: yesBrazilian Journal of Medical and Biological Research
The chemical structure of piperidine has a unique ability to combine with other molecular fragments. This fact makes it possible to actively use it as an effective basis for the creation of new drug-like substances.
E.M. Satbayeva   +10 more
doaj   +1 more source

Efficacy of different dose of dexmedetomidine combined with remifentanil in colonoscopy: a randomized controlled trial

open access: yesBMC Anesthesiology, 2020
Background Dexmedetomidine has advantages during colonoscopy as it allows the patient to cooperate during the procedure. Few studies examined the dexmedetomidine-remifentanil combination.
Li Jia   +5 more
doaj   +1 more source

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