PLXNA3 is overexpressed and promotes cell proliferation and migration in colorectal cancer
Discover OncologyBackground Plexins (PLXNs) are cell surface receptors for class 3 semaphorins and play critical roles in immune regulation and tumorigenesis. Plexin A3 (PLXNA3) is involved primarily in nervous system development, but its function in colorectal cancer ...
Shun Ling +3 more
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B-type Plexins promote the GTPase activity of Ran to affect androgen receptor nuclear translocation in prostate cancer. [PDF]
Cancer Gene Ther, 2023 Garg R, Endzhievskaya S, Williamson M.
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Semaphorins in immune cell function, inflammatory and infectious diseases. [PDF]
Curr Res Immunol, 2023 Thomas R, Yang X.
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Semaphorin 6 Family-An Important Yet Overlooked Group of Signaling Proteins Involved in Cancerogenesis. [PDF]
Cancers (Basel), 2023 Wagner W, Ochman B, Wagner W.
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PLXND1 from the Plexins family is a prognostic factor promoting colon cancer invasion and metastasis. [PDF]
Am J Transl ResChen W, Guo L, Wang Z, Wang Z, Dai X.
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Hybrid in vitro/in silico analysis of low-affinity protein-protein interactions that regulate signal transduction by Sema6D. [PDF]
Protein Sci, 2022 Tanaka T +12 more
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Context-Dependent Dual Roles of the Plexin-B Family in Cancer Progression: Mechanisms and Therapeutic Implications. [PDF]
Cancer Manag ResMao X +10 more
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Semaphorin4A promotes lung cancer by activation of NF-κB pathway mediated by PlexinB1. [PDF]
PeerJ, 2023 Wei X +8 more
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