Results 91 to 100 of about 2,365 (188)

Pushing Frontiers for Proteoglycans

open access: yesProteoglycan Research, Volume 4, Issue 2, April 2026.
ABSTRACT Almost half of proteins have one or more post‐translational glycosylation modifications involving the addition of glycan structures. Proteoglycans are a class of glycosylated proteins with one or more glycosaminoglycan (GAG) chains covalently attached to the core protein.
Marissa L. Maciej‐Hulme
wiley   +1 more source

Soluble Sema4D From γδ T Cells Exerts Osteoblast Inhibition via Plexin‐B/mTOR Signalling Contributing to Pathogenesis of Bisphosphonate‐Related Osteonecrosis of the Jaws

open access: yesCell Proliferation, Volume 59, Issue 4, April 2026.
Schematic summarizing the pathway of sSema4D from γδ T cells inhibiting osteoblast differentiation in BRONJ. ABSTRACT Bisphosphonate‐related osteonecrosis of the jaw (BRONJ) is a severe complication in patients undergoing long‐term bisphosphonate therapy, while our knowledge on the pathogenesis of BRONJ is far from sufficient.
Lingling Ou   +15 more
wiley   +1 more source

Loss of plexin-B3 in hepatocellular carcinoma

open access: yesExperimental and Therapeutic Medicine, 2015
Plexins are the primary receptors of semaphorins, and participate in the majority of intracellular pathways triggered by semaphorins, including the regulation of cell adhesion and the motility of numerous cell types. Recently, several studies have reported that plexins can significantly affect different aspects of cancer cell biology, and the aberrant ...
LIU, YUWU   +7 more
openaire   +3 more sources

Plexins, semaphorins, and scatter factor receptors: A common root for cell guidance signals?

open access: yes, 1999
Semaphorins, the plexin family of semaphorin receptors, and scatter factor receptors share evolutionarily conserved protein modules, such as the semaphorin domain and Met Related Sequences (MRS). All these proteins also have in common a role in mediating
Tamagnone, Luca
core   +1 more source

Nationwide Survey of Atopic Myelitis and Plexin D1‐Immunoglobulin G‐Related Pain

open access: yesAnnals of Clinical and Translational Neurology, Volume 13, Issue 3, Page 593-606, March 2026.
ABSTRACT Objective To elucidate the features of plexin D1‐immunoglobulin (Ig)G‐associated neuropathic pain and its relationship to atopic myelitis (AM) in a nationwide Japanese survey. Methods A preliminary survey questionnaire was sent to 1574 selected departments (neurology and pediatrics/pediatric neurology) to explore the numbers of AM and plexin ...
Jun‐ichi Kira   +10 more
wiley   +1 more source

Semaphorin Signaling in the Development and Function of the Gonadotropin Hormone-Releasing Hormone (GnRH) System

open access: yesFrontiers in Endocrinology, 2013
The semaphorin proteins are among the best-studied families of guidance cues, contributing to morphogenesis and homeostasis in a wide range of tissue types.
Andrea eMessina, Paolo eGiacobini
doaj   +1 more source

Importance of the putative furin recognition site 742RNRR745 for antiangiogenic Sema3C activity in vitro

open access: yesBrazilian Journal of Medical and Biological Research, 2018
Angiogenesis is one of the key processes in the growth and development of tumors. Class-3 semaphorins (Sema3) are characterized as axon guidance factors involved in tumor angiogenesis by interacting with the vascular endothelial growth factor signaling ...
I. Valiulyte   +3 more
doaj   +1 more source

Plxdc2 is a mitogen for neural progenitors.

open access: yesPLoS ONE, 2011
The development of different brain regions involves the coordinated control of proliferation and cell fate specification along and across the neuraxis. Here, we identify Plxdc2 as a novel regulator of these processes, using in ovo electroporation and in ...
Suzanne F C Miller-Delaney   +3 more
doaj   +1 more source

Plexin-Semaphorin Signaling Modifies Neuromuscular Defects in a Drosophila Model of Peripheral Neuropathy

open access: yesFrontiers in Molecular Neuroscience, 2018
Dominant mutations in GARS, encoding the ubiquitous enzyme glycyl-tRNA synthetase (GlyRS), cause peripheral nerve degeneration and Charcot-Marie-Tooth disease type 2D (CMT2D).
Stuart J. Grice   +3 more
doaj   +1 more source

PhenoFam-gene set enrichment analysis through protein structural information

open access: yesBMC Bioinformatics, 2010
Background With the current technological advances in high-throughput biology, the necessity to develop tools that help to analyse the massive amount of data being generated is evident.
Pisabarro M Teresa   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy