Results 81 to 90 of about 2,043 (169)
Biochemical bone biomarkers in plasma cell dyscrasias
British Journal of Haematology, Volume 208, Issue 6, Page 1909-1923, June 2026.Visual abstract depicting that bone turnover markers reflect dynamic alterations in bone remodelling across the spectrum of plasma cell dyscrasias but remain limited by assay variability, biological confounding and incomplete integration with imaging and risk stratification.
Guido Nador +4 more
wiley +1 more source
Frontiers in Endocrinology, 2013 The semaphorin proteins are among the best-studied families of guidance cues, contributing to morphogenesis and homeostasis in a wide range of tissue types.
Andrea eMessina, Paolo eGiacobini
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Loss of plexin-B3 in hepatocellular carcinoma
Experimental and Therapeutic Medicine, 2015 Plexins are the primary receptors of semaphorins, and participate in the majority of intracellular pathways triggered by semaphorins, including the regulation of cell adhesion and the motility of numerous cell types. Recently, several studies have reported that plexins can significantly affect different aspects of cancer cell biology, and the aberrant ...
LIU, YUWU +7 more
openaire +3 more sources
Brazilian Journal of Medical and Biological Research, 2018 Angiogenesis is one of the key processes in the growth and development of tumors. Class-3 semaphorins (Sema3) are characterized as axon guidance factors involved in tumor angiogenesis by interacting with the vascular endothelial growth factor signaling ...
I. Valiulyte +3 more
doaj +1 more source
Plxdc2 is a mitogen for neural progenitors.
PLoS ONE, 2011 The development of different brain regions involves the coordinated control of proliferation and cell fate specification along and across the neuraxis. Here, we identify Plxdc2 as a novel regulator of these processes, using in ovo electroporation and in ...
Suzanne F C Miller-Delaney +3 more
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Frontiers in Molecular Neuroscience, 2018 Dominant mutations in GARS, encoding the ubiquitous enzyme glycyl-tRNA synthetase (GlyRS), cause peripheral nerve degeneration and Charcot-Marie-Tooth disease type 2D (CMT2D).
Stuart J. Grice +3 more
doaj +1 more source
PhenoFam-gene set enrichment analysis through protein structural information
BMC Bioinformatics, 2010 Background With the current technological advances in high-throughput biology, the necessity to develop tools that help to analyse the massive amount of data being generated is evident.
Pisabarro M Teresa +3 more
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Receptor complexes for each of the Class 3 Semaphorins
Frontiers in Cellular Neuroscience, 2012 The Class 3 Semaphorins (Sema3s) are a sub-family of proteins whose known biological roles are varied and growing. The mechanism of action of the Sema3s requires binding to transmembrane receptors that comprise heteromeric complexes of Neuropilins ...
Alan R Harvey
doaj +1 more source
Plexin Activation Relies on an Array of Receptors
PLoS Biology, 2011 ​YoungYoung nerve cells put out cellular extensions called axons that must navigate through a maze of environmental cues in order to find their targets. Making the correct cellular connections is critical to building a functioning nervous system. In order to interpret these external cues, axons use receptor proteins that are directly embedded in the ...
openaire +4 more sources
Impact of semaphorin expression on prognostic characteristics in breast cancer
Breast Cancer: Targets and Therapy, 2018 Ramesh Butti, Totakura VS Kumar, Ramakrishna Nimma, Gopal C Kundu Laboratory of Tumor Biology, Angiogenesis and Nanomedicine Research, National Centre for Cell Science, Savitribai Phule Pune University, Pune, India Abstract: Breast cancer is one of the ...
Butti R, Kumar TVS, Nimma R, Kundu GC
doaj