Results 11 to 20 of about 30,090 (224)
PML, SUMOylation, and Senescence [PDF]
Frontiers in Oncology, 2013 Since its discovery, 25 years ago, promyelocytic leukemia (PML) has been an enigma. Implicated in the oncogenic PML/RARA fusion, forming elusive intranuclear domains, triggering cell death or senescence, controlled by and perhaps controlling SUMOylation… there are multiple PML-related issues.
Hugues eDe Thé +10 more
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Regulation of apoptosis by PML and the PML-NBs [PDF]
Oncogene, 2008 The promyelocytic leukemia protein (PML) is a tumor suppressor identified in acute PML and implicated in the pathogenesis of a variety of tumors. PML is essential for the proper assembly of a nuclear macromolecular structure called the PML nuclear body (PML-NB).
Bernardi R +2 more
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Regulation of NF-κB by PML and PML-RARα [PDF]
Scientific Reports, 2017 AbstractPromyelocytic Leukemia (PML) is a nuclear protein that forms sub-nuclear structures termed nuclear bodies associated with transcriptionally active genomic regions. PML is a tumour suppressor and regulator of cell differentiation. We demonstrate that PML promotes TNFα-induced transcriptional responses by promoting NF-κB activity.
Ahmed, Abrar +8 more
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ALIGNMENT OF HYPERSPECTRAL IMAGERY AND FULL-WAVEFORM LIDAR DATA FOR VISUALISATION AND CLASSIFICATION PURPOSES [PDF]
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2015 The overarching aim of this paper is to enhance the visualisations and classifications of airborne remote sensing data for remote forest surveys. A new open source tool is presented for aligning hyperspectral and full-waveform LiDAR data.
M. Miltiadou +3 more
doaj +1 more source
Журнал инфектологии, 2019 Progressive multifocal leukoencephalopathy (PML) is one of the most severe opportunistic diseases of the central nervous system, which leads to multiple demyelination of brain structures, neurological symptoms and frequent death or disability of the ...
E. A. Samotolkina +3 more
doaj +1 more source
Application of the Reflectionless Discrete Perfectly Matched Layer for Acoustic Wave Simulation
Frontiers in Earth Science, 2022 The perfectly matched layer (PML) is one of the most popular absorbing boundary conditions for simulating seismic waves. In theory, the PML can absorb incident waves at any incident angle and any frequency in a medium. However, numerical reflections will
Yingjie Gao +3 more
doaj +1 more source
Promyelocytic leukemia nuclear body-like structures can assemble in mouse oocytes
Biology Open, 2022 Promyelocytic leukemia (PML) nuclear bodies (PML-NBs), a class of membrane-less cellular organelles, participate in various biological activities. PML-NBs are known as the core-shell-type nuclear body, harboring ‘client’ proteins in their core.
Osamu Udagawa +2 more
doaj +1 more source
Viscoelastic modeling and factor Q for reflection data
Geofísica Internacional, 2012 Los modelos numéricos viscoelásticos, basados en el concepto de mecanismos de dispersión, toman en cuenta las variables de memoria y algunos parámetros de dispersión, a saber los tiempos de relajación de tensión. En la práctica de la geofísica, el factor
Vladimir Sabinin
doaj +1 more source
Patient monitoring during treatment with natalizumab (ORP-24) [PDF]
Neurology Letters, 2023 Natalizumab (Tysabri), a recombinant humanized monoclonal antibody selective for α4- integrin, is indicated for CIS, RRMS, and active SPMS in adults.
Zohreh Abna
doaj
Cells, 2019 SRC-3/AIB1 (Amplified in Breast Cancer-1) is a nuclear receptor coactivator for the estrogen receptor in breast cancer cells. It is also an intrinsically disordered protein when not engaged with transcriptional binding partners and degraded upon ...
Miguel A. Cabrita +3 more
doaj +1 more source