Results 21 to 30 of about 30,090 (224)
Inhibition of Sp1 functions by its sequestration into PML nuclear bodies. [PDF]
PLoS ONE, 2014 Promyelocytic leukemia nuclear bodies (PML NBs) are comprised of PML and a striking variety of its associated proteins. Various cellular functions have been attributed to PML NBs, including the regulation of gene expression.
June Li, Wen-Xin Zou, Kun-Sang Chang
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PML degradation fosters an immunosuppressive and pro-metastatic tumor microenvironment
Molecular & Cellular Oncology, 2017 The tumor suppressive functions of promyelocytic leukemia (PML) have been attributed mainly to its inhibition of various malignant properties of tumor cells.
Ya-Ting Wang, Ruey-Hwa Chen
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Metabolic profiles by 1H-magnetic resonance spectroscopy in natalizumab-associated post-PML lesions of multiple sclerosis patients who survived progressive multifocal leukoencephalopathy (PML). [PDF]
PLoS ONE, 2017 PURPOSE:Early diagnosis and treatment of multiple sclerosis-related progressive multifocal leukoencephalopathy (PML) significantly improve clinical outcomes. However, there is a lack of information regarding the restart of immunomodulatory therapy in the
Ruth Schneider +7 more
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Effects of arsenic on the topology and solubility of promyelocytic leukemia (PML)-nuclear bodies.
PLoS ONE, 2022 Promyelocytic leukemia (PML) proteins are involved in the pathogenesis of acute promyelocytic leukemia (APL). Trivalent arsenic (As3+) is known to cure APL by binding to cysteine residues of PML and enhance the degradation of PML-retinoic acid receptor α
Seishiro Hirano, Osamu Udagawa
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Frontiers in Veterinary Science, 2021 Promyelocytic leukemia (PML) protein is a crucial component of PML-nuclear bodies (PML-NBs). PML and PML-NBs are involved in the regulation of various cellular functions, including the antiviral immune response.
Jingjing Zhu +7 more
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Perspectives in PML: a unifying framework for PML function
Frontiers in Bioscience, 2009 The promyeloctyic leukemia protein (PML) has established activities as a potent repressor of proliferation, and oncogenic transformation, a promoter of apoptosis, an inducer of senescence, and may act as an inhibitor of angiogenesis in mammalian systems. Loss of PML or its nuclear bodies is associated with many human disease states.
Katherine L B, Borden +1 more
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PML inspired transparent metamaterials [PDF]
2016 IEEE International Symposium on Antennas and Propagation (APSURSI), 2016 Perfectly transparent metamaterial structures of arbitrary shapes, constructed from coordinate stretching and contractions, are presented. Coordinate stretching has been used for 2 decades in perfectly matched layers (PMLs) to electromagnetically simulate infinite domains in numerical techniques, but this concept is applied here for the first time to ...
Chamanara, Nima, Caloz, Christophe
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Cells, 2019 Promyelocytic leukemia (PML) bodies are dynamic intracellular structures that recruit and release a variety of different proteins in response to stress, virus infection, DNA damage and cell cycle progression. While PML bodies primarily are regarded as nuclear compartments, they are forced to travel to the cytoplasm each time a cell divides, due to ...
Anna Lång, Emma Lång, Stig Ove Bøe
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PML and PML-like exonucleases restrict retrotransposons in jawed vertebrates
Nucleic Acids Research, 2022 ABSTRACTWe have uncovered a novel role for the promyelocytic leukemia (PML) gene and novel PML-like DEDDh exonucleases in the maintenance of genome stability through the restriction of LINE-1 (L1) retrotransposition in jawed vertebrates. Although the PML tumour suppressor protein in mammals is SUMOylated and forms nuclear bodies, we found that the ...
Sabateeshan Mathavarajah +12 more
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Pemodelan Awal Ground Penetrating Radar dengan Metode Discontinuous Galerkin dan PML Berenger
Jurnal Nasional Teknik Elektro dan Teknologi Informasi, 2016 This paper discusses the development of Discontinuous Galerkin method, which has both linear shape function and weight function, for modeling Ground Penetrating Radar (GPR) in heterogeneous media.
Pranowo
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