Results 31 to 40 of about 30,090 (224)
The Role of Promyelocytic Leukemia Nuclear Bodies During HPV Infection
Frontiers in Cellular and Infection Microbiology, 2020 Promyelocytic leukemia (PML) nuclear bodies (NBs) are highly dynamic subnuclear structures. Their name giving major component, PML protein, is essential for their formation.
Lucile G. Guion +3 more
doaj +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Preparation of LaB6 Powders via Calciothermic Reduction using Mechanochemistry and Acid Leaching
KONA Powder and Particle Journal, 2015 This study reports a room temperature mechanochemical route for the synthesis of LaB6 powders originated from related metal oxide powders as La2O3 and B2O3.
Duygu Ağaoğulları +3 more
doaj +1 more source
Requirement of PML SUMO interacting motif for RNF4- or arsenic trioxide-induced degradation of nuclear PML isoforms. [PDF]
PLoS ONE, 2012 PML, the organizer of nuclear bodies (NBs), is expressed in several isoforms designated PMLI to VII which differ in their C-terminal region due to alternative splicing of a single gene.
Mohamed Ali Maroui +5 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 Promyelocytic leukemia nuclear bodies (PML NBs) are multi-protein assemblies representing distinct sub-nuclear structures. As phase-separated molecular condensates, PML NBs exhibit liquid droplet-like consistency.
Upayan Patra, Stefan Müller
doaj +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
PLoS ONE, 2011 The PML tumor suppressor is the founding component of the multiprotein nuclear structures known as PML nuclear bodies (PML-NBs), which control several cellular functions including apoptosis and antiviral effects.
Feroz Sarkari +3 more
doaj +1 more source
International Journal for Numerical Methods in Engineering, 2011 SUMMARYThis brief article outlines a new and rather simple method for obtaining the finite element matrices for a perfectly matched layer used for elastic wave propagation in the context of a frequency‐domain formulation. For this purpose, we introduce a fairly mild simplification, which allows applying the stretching functions directly to the mass and
Kausel, Eduardo A. +1 more
openaire +4 more sources
Advanced Engineering Materials, Volume 27, Issue 6, March 2025.ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur +5 more
wiley +1 more source
Crosstalk between p53 modifiers at PML bodies
Molecular & Cellular Oncology, 2018 Tumor protein p53 (TP53, best known as p53), the most frequently mutated tumor suppressor in cancer, plays a central role in cell fate decisions induced by DNA damage.
Sonja Matt, Thomas G Hofmann
doaj +1 more source