Results 21 to 30 of about 6,165 (196)

Podocalyxin : A Marker of Blasts in Acute Leukemia [PDF]

American Journal of Clinical Pathology, 2005
Podocalyxin is a CD34 family member expressed by podocytes, vascular endothelium, mesothelium, and a subset of hematopoietic progenitors. Podocalyxin expression was not observed in the hematopoietic cells of normal adult bone marrow samples. However, podocalyxin was expressed by blasts in 30 (77%) of 39 cases of acute myeloid leukemia (AML), 22 (81 ...
Todd W, Kelley, David, Huntsman, Kelly M, McNagny, Calvin D, Roskelley, Eric D, Hsi   +4 more
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Podocalyxin in Rat Platelets and Megakaryocytes [PDF]

The American Journal of Pathology, 1999
Podocalyxin is a membrane protein of rat podocytes and endothelial cells. It has not been described in other cell types, and no amino acid or DNA sequence data are available about it. Here we show that podocalyxin antigens are present in rat platelets and megakaryocytes.
A, Miettinen, M L, Solin, J, Reivinen, E, Juvonen, R, Väisänen, H, Holthöfer   +5 more
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Levels of serum podocalyxin in preeclampsia and relationship with maternal echocardiographic and doppler ultrasound parameters [PDF]

Folia Medica, 2022
Introduction: Podocalyxin (PCX) is an indicator of glomerular injury. Aside from the kidney, it is expressed in the endothelial cells of various organs.
Asparuh G. Nikolov, Nikola K. Popovski, Svetla Blazheva   +2 more
doaj   +3 more sources

Urinary podocalyxin: Is it a real index of disease activity in egyptian patients lupus nephritis?

Saudi Journal of Kidney Diseases and Transplantation, 2020
Systemic lupus erythematosus (SLE) is an inflammatory autoimmune disease characterized by production of a number of antinuclear antibodies. Podocyte injury is an important feature and can be detected by several markers including podocalyxin.
Ahmed Fayed, Mahmoud M Elnokeety, Mohamed Elyamny, Hany Hammad, Dina Hesham Ahmed Soliman, Reham Abdelghany Ahmed   +5 more
doaj   +1 more source

Podocalyxin regulates pronephric glomerular development in zebrafish [PDF]

Physiological Reports, 2013
Vertebrate glomerular podocytes possess a highly sialylated transmembrane glycoprotein, Podocalyxin. In mammals, the sialic acid of Podocalyxin plays a crucial role in the formation of the characteristic podocyte architecture required for glomerular filtration. We examined the function of Podocalyxin in the developing zebrafish pronephros by disrupting
Ichimura, Koichiro, Powell, Rebecca, Nakamura, Tomomi, Kurihara, Hidetake, Sakai, Tatsuo, Obara, Tomoko   +5 more
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Podocalyxin regulates murine lung vascular permeability by altering endothelial cell adhesion. [PDF]

PLoS ONE, 2014
Despite the widespread use of CD34-family sialomucins (CD34, podocalyxin and endoglycan) as vascular endothelial cell markers, there is remarkably little known of their vascular function.
Erin J Debruin, Michael R Hughes, Christina Sina, Alex Lu, Jessica Cait, Zhiqi Jian, Martin Lopez, Bernard Lo, Thomas Abraham, Kelly M McNagny   +9 more
doaj   +1 more source

Podocalyxin Is a Marker of Poor Prognosis in Pancreatic Ductal Adenocarcinoma. [PDF]

PLoS ONE, 2015
Podocalyxin-like 1 is a transmembrane glyco-protein whose overexpression associates in many cancers with poor prognosis and unfavorable clinicopathological characteristics.
Kapo Saukkonen, Jaana Hagström, Harri Mustonen, Anne Juuti, Stig Nordling, Christian Fermér, Olle Nilsson, Hanna Seppänen, Caj Haglund   +8 more
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Recombinant erythropoietin treatment improves serum podocyte marker levels in diabetic kidney disease

Advances in Biomarker Sciences and Technology, 2023
Background: Recombinant human erythropoietin (rHuEPO) is an effective treatment for renal anemia. Recently, there is evidence to suggest that rHuEPO may reduce podocyte injury in diabetic kidney disease (DKD).
Lingfeng Zeng, Jack Kit-Chung Ng, Winston Wing-Shing Fung, Gordon Chun-Kau Chan, Kai-Ming Chow, Cheuk-Chun Szeto   +5 more
doaj   +1 more source

Relationship between Elevated Maternal Serum Podocalyxin Concentrations with Blood Pressure Values and Routine Laboratory Parameters in Preeclampsia [PDF]

Journal of Biomedical & Clinical Research, 2021
Podocalyxin (PCX) is a glycoprotein member of the CD34 transmembrane sialomucin family and covers the surface of podocytes. It is assumed to be a marker of glomerular endothelial injury. In conditions, podocalyxin excretion in the urine is increased as a
Nikola Popovski, Asparuh Nikolov, Yordan Popov, Svetla Blazheva   +3 more
doaj   +3 more sources

The Role of Podocalyxin in Health and Disease [PDF]

Journal of the American Society of Nephrology, 2009
Podocalyxin, a sialomucin most closely related to CD34 and endoglycan, is expressed by kidney podocytes, hematopoietic progenitors, vascular endothelia, and a subset of neurons; aberrant expression has recently been implicated in a range of cancers.
Julie S, Nielsen, Kelly M, McNagny
openaire   +2 more sources