Results 101 to 110 of about 7,104 (202)

3D Bioprinted Renal Constructs Using Kidney‐Specific ECM Bioink System on Kidney Regeneration

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 24, September 18, 2025.
A kidney‐specific bioink derived from decellularized porcine kidney tissue supports the encapsulation, viability, and maturation of human primary kidney cells within 3D bioprinted constructs. In vivo, it also promotes the recruitment of host renal progenitor cells, collectively enhancing structural and functional regeneration of renal tissue.
Gabriel Carreno‐Galeano   +4 more
wiley   +1 more source

A Review of Focal Segmental Glomerulosclerosis Classification With a Focus on Genetic Associations

open access: yesKidney Medicine
Focal segmental glomerulosclerosis (FSGS) defines a distinct histologic pattern observed in kidney tissue that is linked to several distinct underlying causes, all converging on the common factor of podocyte injury.
Marco Bonilla   +4 more
doaj   +1 more source

Thymol alleviates AGEs-induced podocyte injury by a pleiotropic effect via NF-κB-mediated by RhoA/ROCK signalling pathway

open access: yesCell Adhesion & Migration, 2020
Advanced glycation end products (AGE) are those of the most powerful pathogenic factors that related to diabetic complications. In our study, we investigated the beneficial effects of thymol on AGE induced cell injury and apoptosis in human podocytes ...
Qinglian Wang   +5 more
doaj   +1 more source

Low renal but high extrarenal phenotype variability in Schimke immuno-osseous dysplasia [PDF]

open access: yes, 2017
Schimke immuno-osseous dysplasia (SIOD) is a rare multisystem disorder with early mortality and steroid-resistant nephrotic syndrome (SRNS) progressing to end-stage kidney disease.
Boyer, Olivia   +5 more
core   +1 more source

Intravital imaging reveals angiotensin II–induced transcytosis of albumin by podocytes [PDF]

open access: yes, 2015
Albuminuria is a hallmark of kidney disease of various etiologies and usually caused by deterioration of glomerular filtration barrier integrity. We recently showed that angiotensin II (Ang II) acutely increases albumin filtration in the healthy kidney.
Castrop, Hayo   +6 more
core   +1 more source

Nephrin and Podocin Expression Around the Onset of Puromycin Aminonucleoside Nephrosis

open access: yesJournal of Pharmacological Sciences, 2005
Decreased expression levels of the glomerular slit membrane proteins, nephrin and podocin, have been reported after the onset of puromycin aminonucleoside (PA) nephrosis. We examined nephrin and podocin expressions prior to the onset of proteinuria of PA nephrosis to elucidate the proteinuria induction mechanism of PA.
Makoto, Hosoyamada   +7 more
openaire   +3 more sources

Effects of Quinazolinones on the Development of BALB/c Mice [PDF]

open access: yes, 2009
Objective(s)Quinazolinones are heterocyclic components (able to form cyclized compounds) which have several medical effects such as anti-malarial, spasmolytic, anti-microbial, sedative, etc.
Daryush Minaei Tehrani   +3 more
core  

肥胖患者肾小球Podocin的表达减少及临床意义

open access: yesZhongguo shiyan zhenduanxue, 2012
目的检测肥胖患者肾小球足细胞上Podocin的蛋白分布和表达,探讨Podocin在肥胖导致蛋白尿中的变化及意义。方法收集肾脏切除病理标本,取其相对正常肾脏皮质,体重指数(BMI)≥28kg/m2者16例作为肥胖组(Ob组 ...
杜娟   +5 more
doaj  

Focal segmental glomerulosclerosis: Molecular genetics and targeted therapies [PDF]

open access: yes, 2015
Recent advances show that human focal segmental glomerulosclerosis (FSGS) is a primary podocytopathy caused by podocyte-specific gene mutations including NPHS1, NPHS2, WT-1, LAMB2, CD2AP, TRPC6, ACTN4 and INF2.
Chen, Ying Maggie, Liapis, Helen
core   +2 more sources

An essential role of the universal polarity protein, aPKClambda, on the maintenance of podocyte slit diaphragms.

open access: yesPLoS ONE, 2009
Glomerular visceral epithelial cells (podocytes) contain interdigitated processes that form specialized intercellular junctions, termed slit diaphragms, which provide a selective filtration barrier in the renal glomerulus.
Tomonori Hirose   +9 more
doaj   +1 more source

Home - About - Disclaimer - Privacy