Results 101 to 110 of about 7,139 (201)
Advanced Biology, Volume 9, Issue 9, September 2025.The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran +5 more
wiley +1 more source
Effect of Sirt1 on high glucose-induced exosome release from podocytes [PDF]
精准医学杂志Objective To investigate the effect of nicotinamide adenine dinucleotide-dependent deacetylase 1 (Sirt1) on high glucose-induced exosome release from podocytes. Methods Immortalized mouse podocytes MPC5 were divided into six groups: normal glucose group (
DING Lin, ZHOU Yan, LIU Shanshan, LIU Nanchi, MA Ruixia
doaj +1 more source
3D Bioprinted Renal Constructs Using Kidney‐Specific ECM Bioink System on Kidney Regeneration
Advanced Healthcare Materials, Volume 14, Issue 24, September 18, 2025.A kidney‐specific bioink derived from decellularized porcine kidney tissue supports the encapsulation, viability, and maturation of human primary kidney cells within 3D bioprinted constructs. In vivo, it also promotes the recruitment of host renal progenitor cells, collectively enhancing structural and functional regeneration of renal tissue.
Gabriel Carreno‐Galeano +4 more
wiley +1 more source
Advanced Science, Volume 12, Issue 33, September 4, 2025.Prevention and treatment of diabetic kidney disease (DKD) have become a major global public health challenge. This study shed new light on the underlying pathogenic mechanisms of podocyte injury in DKD and highlights the therapeutic potential of mitigating podocyte injury through inhibition of the RIPK3/NF‐κB p65‐mediated inflammatory response as a ...
Lu'an Li +10 more
wiley +1 more source
Cell Adhesion & Migration, 2020 Advanced glycation end products (AGE) are those of the most powerful pathogenic factors that related to diabetic complications. In our study, we investigated the beneficial effects of thymol on AGE induced cell injury and apoptosis in human podocytes ...
Qinglian Wang +5 more
doaj +1 more source
Low renal but high extrarenal phenotype variability in Schimke immuno-osseous dysplasia [PDF]
, 2017 Schimke immuno-osseous dysplasia (SIOD) is a rare multisystem disorder with early mortality and steroid-resistant nephrotic syndrome (SRNS) progressing to end-stage kidney disease.
Boyer, Olivia +5 more
core +1 more source
Advanced NanoBiomed Research, Volume 5, Issue 9, September 2025.Kidney stones cause significant pain and healthcare costs. Current prediction, diagnosis, and treatment options are limited. Extracellular vesicles (EVs), rich in proteins, lipids, and nucleic acids, offer a promising solution. This review explores the roles of EVs in kidney stone management, highlighting their potential as biomarkers and therapeutic ...
Wang Zhu +3 more
wiley +1 more source
自然発症高血圧ラットにおける七物降下湯の腎保護作用 [PDF]
, 2015 富山大学・富医薬博甲第177号・馬躍・2015/09/28・★論文非公開 ...
馬 躍
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Nephrin and Podocin Expression Around the Onset of Puromycin Aminonucleoside Nephrosis
Journal of Pharmacological Sciences, 2005 Decreased expression levels of the glomerular slit membrane proteins, nephrin and podocin, have been reported after the onset of puromycin aminonucleoside (PA) nephrosis. We examined nephrin and podocin expressions prior to the onset of proteinuria of PA nephrosis to elucidate the proteinuria induction mechanism of PA.
Makoto, Hosoyamada +7 more
openaire +3 more sources
Activation of podocyte Notch mediates early Wt1 glomerulopathy [PDF]
, 2018 The Wilms' tumor suppressor gene, WT1, encodes a zinc finger protein that regulates podocyte development and is highly expressed in mature podocytes. Mutations in the WT1 gene are associated with the development of renal failure due to the formation of ...
Alex K. Virasami +58 more
core +1 more source