Results 61 to 70 of about 5,352 (196)
Frontiers in Genetics, 2020 IntroductionPathogenic variants in different genes have been described as involved in the development of familial focal segmental glomerulosclerosis (FSGS).
Michelle T. P. Riguetti +6 more
doaj +1 more source
PodocinTVV339, 340,341 regulates the surface expression of podocin.
, 2013 A. Amino acid-triplets within podocin335–350 were mutated using a Quickchange approach. Mutated plasmids were transiently expressed in HeLa cells and localization of mutants was assessed by immunofluorescence using anti-Flag antibody.
Markus Gödel (152664) +4 more
core +1 more source
Compartment‐Specific Immune Remodeling of Renal Aging With C1q‐Associated Podocyte Activation
The FASEB Journal, Volume 40, Issue 11, 15 June 2026.Aging repatterns the renal immune response in a compartment‐specific manner, distinct from chronic kidney disease (CKD) adaptation. Glomerular aging features C1q‐associated podocyte activation and macrophage engagement, whereas tubulointerstitial aging is marked by B‐cell aggregation and tertiary lymphoid structure expansion.
Ju‐Young Moon +10 more
wiley +1 more source
A C-terminal domain regulates plasma membrane localization of podocin.
, 2013 A. Immunofluorescence for a transiently expressed, Flag-tagged truncation of podocin (podocin1–285) reveals increased plasma membrane localization in comparison with podocin wild type in HeLa-cells (b and a respectively). B.
Markus Gödel (152664) +4 more
core +1 more source
Scientific Reports, 2021 Podocyte abnormalities are common mechanism driving the progression of glomerular diseases, which account for most chronic kidney diseases (CKDs). However, the role of podocyte in the mechanism of high-risk long-term CKD caused by prematurity has not ...
Fangrui Ding +4 more
doaj +1 more source
The Plant Journal, Volume 126, Issue 3, May 2026.SUMMARY Plasma membranes (PM) contain myriads of diverse nanodomains that correspond to nanometric scale structures enriched in specific lipids and proteins acting as signaling/regulation hubs involved in diverse biological processes. So far, how PM nanodomains are formed and maintained in plant cells remains largely unknown.
Michal Daněk +18 more
wiley +1 more source
Hypertension in Pregnancy, 2020 Aim The study explored the beneficial effects of repeated episodes of whole body hypoxic perconditioning (WHPC) on preeclampsia (PE)-like symptoms in rats.
Yan Li +3 more
doaj +1 more source
Genipin restores podocin and WT1 expression in cultured podocytes.
, 2013 (a) Western blot analysis shows the results of podocin and WT1 in podocytes incubated with D-Glucose for different time periods as indicated. The membrane was reprobed with actin to confirm equal loading of each lane.
Yang Zhou (65942) +9 more
core +1 more source
Advanced NanoBiomed Research, Volume 6, Issue 4, April 2026.This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari +5 more
wiley +1 more source
Small Science, Volume 6, Issue 3, March 2026.Current treatments for severe lupus nephritis are limited by side effects due to poor drug targeting. This review explores how smart nanomaterials—like liposomes and biomimetic carriers—can precisely deliver drugs to overactive immune cells and the kidneys. These nanotherapeutics enhance efficacy, reduce toxicity, and enable combination strategies. The
Cheng Zhou +6 more
wiley +1 more source