Results 101 to 110 of about 15,256 (194)

PARPs in liver diseases

npj Gut and Liver
Poly(ADP-ribose) polymerases (PARPs) comprise a family of 17 enzymes were initially identified for their essential roles in DNA damage repair and maintenance of genomic stability. Emerging evidence has unveiled their critical involvement in various liver
Jiaxin Xia, Xiao Tang, Qihua Zhu, Yizhu Xu   +3 more
doaj   +1 more source

Brain tissue transcriptomic analysis of SIV-infected macaques identifies several altered metabolic pathways linked to neuropathogenesis and poly (ADP-ribose) polymerases (PARPs) as potential therapeutic targets. [PDF]

J Neurovirol, 2021
Mavian C, Ramirez-Mata AS, Dollar JJ, Nolan DJ, Cash M, White K, Rich SN, Magalis BR, Marini S, Prosperi MCF, Amador DM, Riva A, Williams KC, Salemi M.   +13 more
europepmc   +1 more source

The Arabidopsis thaliana Poly(ADP-Ribose) Polymerases 1 and 2 Modify DNA by ADP-Ribosylating Terminal Phosphate Residues. [PDF]

Front Cell Dev Biol, 2020
Taipakova S, Kuanbay A, Saint-Pierre C, Gasparutto D, Baiken Y, Groisman R, Ishchenko AA, Saparbaev M, Bissenbaev AK.   +8 more
europepmc   +1 more source

cDNAs encoding the large subunit of human replication factor C [PDF]

, 1993
Replication factor C (RFC) is a multisubunit, DNA polymerase accessory protein required for the coordinated synthesis of both DNA strands during simian virus 40 DNA replication in vitro. Previous studies have shown that RFC is a DNA-dependent ATPase that
Bunz, F., Kobayashi, R., Stillman, B.
core  

The role of poly(ADP-ribose) polymerases in manganese exposed Caenorhabditis elegans. [PDF]

J Trace Elem Med Biol, 2020
Neumann C, Baesler J, Steffen G, Nicolai MM, Zubel T, Aschner M, Bürkle A, Mangerich A, Schwerdtle T, Bornhorst J.   +9 more
europepmc   +1 more source

Cell Death Response to DNA Damage. [PDF]

, 2019
The cell death response to DNA damage is discussed in this Perspectives piece with cancer as the backdrop because DNA damaging agents (DDA) are widely used to treat cancer.
Wang, Jean YJ
core   +1 more source

ARTD2 activity is stimulated by RNA [PDF]

, 2017
ADP-ribosyltransferases (ARTs) are important enzymes that regulate the genotoxic stress response and the maintenance of genome integrity. ARTD1 (PARP1) and ARTD2 (PARP2) are homologous proteins that modify themselves and target proteins by the addition ...
Bär, Dominik, Hottiger, Michael O., Léger, Karolin, Santoro, Raffaella, Savić, Nataša   +4 more
core  

PARP inhibition protects against alcoholic and non-alcoholic steatohepatitis [PDF]

, 2018
K
Auwerx, Johan, Bai, Péter, Boulares, A. Hamid, Cao, Zongxian, Gao, Bin, Gariani, Karim, Godlewski, Grzegorz, Haskó, György, Holovac, Eileen, Horváth, Béla, Liaudet, Lucas, Mukhopadhyay, Partha, Németh, Balázs Tamás, Pacher, Pál, Park, Ogyi, Persidsky, Yuri, Pálóczi, János, Rajesh, Mohanraj, Ryu, Dongryeol, Varga, Zoltán V., Wang, Wei, Xu, Ming-Jiang, Zhou, Zhou   +22 more
core  

Poly(ADP-ribose) polymerases as modulators of mitochondrial activity [PDF]

, 2019
Bai, Péter, Fodor, Tamás, Liaudet, Lucas, Nagy, Lilla Nikoletta, Pacher, Pál   +4 more
core   +1 more source

Correction for Brady et al., "Poly(ADP-Ribose) Polymerases in Host-Pathogen Interactions, Inflammation, and Immunity". [PDF]

Microbiol Mol Biol Rev, 2019
Brady PN, Goel A, Johnson MA.
europepmc   +1 more source