Results 71 to 80 of about 973,687 (259)
PLoS PathogensPolyamines are critical cellular components that regulate a variety of processes, including translation, cell cycling, and nucleic acid metabolism. The polyamines, putrescine, spermidine, and spermine, are found abundantly within cells and are positively-
Yazmin E Cruz-Pulido +9 more
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Polyamine Drug Discovery: Synthetic Approaches to Therapeutic Modulators of Polyamine Metabolism
, 2011 Numerous synthetic compounds have been described that either act as inhibitors of enzymes involved in polyamine metabolism or otherwise modulate these pathways.
Patrick M. Woster
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Porphyrin‐Based Porous Materials for Antibacterial Applications
Advanced Science, EarlyView.Porphyrin‐based porous materials have excellent photophysical properties and tunable structures for high‐efficiency antibacterial therapy. This review comprehensively discusses the structural design strategies and synthetic pathways of the four main types of porphyrin‐based porous materials, summarizes their cross‐domain antimicrobial applications, and
Xiao‐Xue Liang +4 more
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Differences in Polyamine Metabolism between Carcinomatous and Uninvolved Human Breast Tissues
The International Journal of Biological Markers, 1986 The polyamine biosynthetic enzymes ODC and SAMDC show higher activity in carcinomatous human breast tissue than in uninvolved tissue of the same breast; the interconversion enzyme PAO shows significantly lower activity in carcinomatous than uninvolved ...
Marta Romano +4 more
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Dissecting rice polyamine metabolism under controlled long-term drought stress.
PLoS ONE, 2013 A selection of 21 rice cultivars (Oryza sativa L. ssp. indica and japonica) was characterized under moderate long-term drought stress by comprehensive physiological analyses and determination of the contents of polyamines and selected metabolites ...
Phuc Thi Do +7 more
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Oil for the cancer engine: The cross-talk between oncogenic signaling and polyamine metabolism
, 2018 Polyamine metabolism exhibits tight cross-talk with oncogenic signaling, thus playing a central role in cancer dynamics.
Carracedo, Arkaitz +5 more
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Animal Research and One Health, EarlyView.Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang +6 more
wiley +1 more source
Frontiers in Plant ScienceIntroductionSugarcane endophytic nitrogen-fixing bacterium Klebsiella variícola DX120E displayed broad impact on growth, but the exact biological mechanism, especially polyamines (PAs) role, is still meager.MethodsTo reveal this relationship, the content
Ying Qin +10 more
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Cells, 2019 Hedgehog (Hh) signaling is a critical developmental regulator and its aberrant activation, due to somatic or germline mutations of genes encoding pathway components, causes Basal Cell Carcinoma (BCC) and medulloblastoma (MB).
Sonia Coni +5 more
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, 2022 High temperature is a huge threat to lettuce production in the world, and spermidine (Spd) has been shown to improve heat tolerance in lettuce, but the action mechanism of Spd and the role of polyamine metabolism are still unclear. The effects of Spd and
Shuangxi Fan +9 more
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