Results 11 to 20 of about 9,343 (180)
Biomolecules, 2023 The triamine spermidine is a key metabolite of the polyamine pathway. It plays a crucial role in many infectious diseases caused by viral or parasitic infections.
Annette Kaiser
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Frontiers in Pharmacology, 2020 Non-small cell lung cancer (NSCLC) is the most lethal and prevalent type of lung cancer. In almost all types of cancer, the levels of polyamines (putrescine, spermidine, and spermine) are increased, playing a pivotal role in tumor proliferation ...
Freddy López-Contreras +9 more
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Cells, 2021 In plants, many of the enzymes in polyamine metabolism are encoded by multiple genes, whose expressions are differentially regulated under different physiological conditions.
Yusaku Yariuchi +3 more
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Agriculture, 2022 Many effects of polyamines (PAs) are well known in plant developmental processes; however, the significance of their catabolism is not well understood. Copper amine oxidase (CuAO) is involved in the degradation of diamine putrescine (Put).
Ágnes Szepesi +4 more
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Semicarbazide diminishes the signs of bleomycin-induced pulmonary fibrosis in rats [PDF]
The Ukrainian Biochemical Journal, 2021 The pathogenesis of pulmonary fibrosis (PF) is accompanied by extracellular matrix (ECM) deposition, oxidative stress, and inflammation progression, as well as hyperactivation of amine oxidases (AOs), which contribute to disease manifestation.
O. O. Hudkova +5 more
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Involvement of Polyamine Oxidase in Wound Healing [PDF]
Plant Physiology, 2007 AbstractHydrogen peroxide (H2O2) is involved in plant defense responses that follow mechanical damage, such as those that occur during herbivore or insect attacks, as well as pathogen attack. H2O2 accumulation is induced during wound healing processes as well as by treatment with the wound signal jasmonic acid.
Angelini, R. +6 more
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Polyamine Oxidase from Water Hyacinth [PDF]
Plant Physiology, 1987 Polyamine oxidase was purified to homogeneity from leaves of water hyacinth by the criterion of sodium dodecyl sulfate gel electrophoresis (SDS disc PAGE). The enzyme showed a high specificity for spermidine and spermine (K(m) values 28 micromolar and 20 micromolar, respectively).
H, Yanagisawa +4 more
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Inhibition of Lymphocyte Proliferation by Polyamines Requires Ruminant-Plasma Polyamine Oxidase [PDF]
European Journal of Biochemistry, 1979 Spermine and spermidine in vitro are potent inhibitors of proliferation of phytohaemagglutinin-stimulated rat thymic lymphocytes, lymphoma cells and human lymphoblastic leukaemia cells, but only in media supplemented by foetal calf serum. This inhibition is shown to be due to a bovine plasma polyamine oxidase, with a high specificity for these ...
J C, Allen +4 more
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The tree of life of polyamine oxidases [PDF]
Scientific Reports, 2020 AbstractPolyamine oxidases (PAOs) are characterized by a broad variability in catalytic properties and subcellular localization, and impact key cellular processes in diverse organisms. In the present study, a comprehensive phylogenetic analysis was performed to understand the evolution of PAOs across the three domains of life and particularly within ...
Salvi D., Tavladoraki P.
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Modulation of polyamine catabolism in pea seedlings by calcium during salinity stress
Plant Protection Science, 2012 The relation of polyamine catabolism in the response of Pisum sativum to salinity stress was investigated. Pea seedlings were grown in increasing concentrations of Na+ or K+ or at different concentration ratios of these ions. We studied the effect of Ca2+
Jana Piterková +4 more
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