Results 11 to 20 of about 55,739 (236)

The Toughest Material in the Plant Kingdom: An Update on Sporopollenin

open access: yesFrontiers in Plant Science, 2021
The extreme chemical and physical recalcitrance of sporopollenin deems this biopolymer among the most resilient organic materials on Earth. As the primary material fortifying spore and pollen cell walls, sporopollenin is touted as a critical innovation ...
Etienne Grienenberger   +1 more
doaj   +1 more source

A Genomic Survey of the Natural Product Biosynthetic Potential of Actinomycetes Isolated from New Zealand Lichens

open access: yesmSystems, 2023
Actinomycetes are prolific producers of industrially valuable and medically important compounds. Historically, the most efficient method of obtaining compounds has been bioactivity-guided isolation and characterization of drug-like molecules from ...
Peng Hou   +5 more
doaj   +1 more source

Cytotoxic Polyketide Metabolites from a Marine Mesophotic Zone Chalinidae Sponge-Associated Fungus Pleosporales sp. NBUF144

open access: yesMarine Drugs, 2021
Two new polyketide natural products, globosuxanthone F (1), and 2′-hydroxy bisdechlorogeodin (2), were isolated from the fungus Pleosporales sp. NBUF144, which was derived from a 62 m deep Chalinidae family sponge together with four known metabolites, 3 ...
Jing Zhou   +10 more
doaj   +1 more source

Biocatalytic Synthesis of Stereospecific Triketide Lactones using Polyketide Synthases [PDF]

open access: yes, 2016
Polyketide synthases are modular enzymes that create and modify large acyl chains. The domains and modules of polyketide synthases allow us to create molecules that resemble naturally occurring products by applying a biocatalytic in vitro in vivo ...
Alexander, Bradley
core   +1 more source

Dictyostelium: An Important Source of Structural and Functional Diversity in Drug Discovery

open access: yesCells, 2018
The cellular slime mold Dictyostelium discoideum is an excellent model organism for the study of cell and developmental biology because of its simple life cycle and ease of use.
Yuzuru Kubohara, Haruhisa Kikuchi
doaj   +1 more source

Nomimicins B–D, new tetronate-class polyketides from a marine-derived actinomycete of the genus Actinomadura

open access: yesBeilstein Journal of Organic Chemistry, 2021
Three new tetronate-class polyketides, nomimicins B, C, and D, along with nomimicin, hereafter named nomimicin A, were isolated from the culture extract of Actinomadura sp.
Zhiwei Zhang   +9 more
doaj   +1 more source

New Polyketides from a Hydrothermal Vent Sediment Fungus Trichoderma sp. JWM29-10-1 and Their Antimicrobial Effects

open access: yesMarine Drugs, 2022
Marine fungi-derived secondary metabolites are still an important source for the discovery of potential antimicrobial agents. Here, five new polyketides (1, 2, and 6–8) and seven known compounds (3–5 and 9–12) were obtained from the culture of the marine-
Changrong Lai   +8 more
doaj   +1 more source

Antibacterial Polyketides Isolated from the Marine-Derived Fungus Fusarium solani 8388

open access: yesJournal of Fungi, 2023
Seven new polyketides named fusarisolins F-K (1–6) and fusarin I (7) were isolated from the marine-derived fungus Fusarium solani 8388, together with the known anhydrojavanicin (8), 5-deoxybostry coidin (9), and scytalol A (10).
Cankai Lin   +9 more
doaj   +1 more source

Aspergillus westerdijkiae polyketide synthase gene “aoks1” is involved in the biosynthesis of ochratoxin A [PDF]

open access: yes, 2009
OchratoxinA (OTA) is a potential nephrotoxic, teratogenic, immunogenic, hepatotoxic and carcinogenic mycotoxin, produced by Aspergillus westerdijkiae NRRL 3174.
Atoui, Ali   +4 more
core   +2 more sources

A New Polyketide from the Endophytic Fungus Penicillium chermesinum

open access: yesIndonesian Journal of Chemistry, 2017
A new polyketide derivative, 2-chloro-3,4,7-trihydroxy-9-methoxy-1-methyl-6H-benzo[c]chromen-6-one (1), was isolated from the endophytic fungus Penicillium chermesinum.
Cici Darsih   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy