Healthy and premature aging of monocytes and macrophages [PDF]
Frontiers in ImmunologyAging is associated with immunosenescence, a decline in immune functions, but also with inflammaging, a chronic, low-grade inflammation, contributing to immunosenescence.
Syamantak Basu +3 more
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Premature aging in genetic diseases: what conclusions can be drawn for physiological aging [PDF]
Frontiers in Aging, 2023 According to current views the major hallmarks of physiological aging may be subdivided into three categories, primary causes of cellular damage (genomic instability, telomere attrition, loss of proteostasis, epigenetic alterations and compromised ...
Filip Milosic +2 more
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Premature aging and metabolic diseases: the impact of telomere attrition [PDF]
Frontiers in AgingDriven by genetic and environmental factors, aging is a physiological process responsible for age-related degenerative changes in the body, cognitive decline, and impaired overall wellbeing.
Sandhya Jinesh +2 more
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Gut microbial composition associated with risk of premature aging in women with Yin-deficiency constitution [PDF]
Frontiers in Cellular and Infection MicrobiologyBackgroundYin-deficiency constitution (YinDC) refers to a traditional Chinese medicine concept, characterized by an imbalance state that includes an imbalance in the gut microbiota, resulting from a relative deficiency of Yin fluids within the body.
Yingying Zhai +15 more
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Molecular signatures of premature aging in Major Depression and Substance Use Disorders [PDF]
Scientific DataMajor depressive disorder (MDD) and substance-use disorders (SUDs) often lead to premature aging, increasing vulnerability to cognitive decline and other forms of dementia. This study utilized advanced systems bioinformatics to identify aging “signatures”
Anna Onisiforou +2 more
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Premature aging in telomerase-deficient zebrafish [PDF]
Disease Models & Mechanisms, 2013 SUMMARY The study of telomere biology is crucial to the understanding of aging and cancer. In the pursuit of greater knowledge in the field of human telomere biology, the mouse has been used extensively as a model.
Monique Anchelin +5 more
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Premature or pathological aging: longevity [PDF]
Brazilian Journal of Food Technology, 2017 The main objective of this literature review was to summarize and characterize the main factors and events that may negatively influence quality of life and human longevity.
Valdemiro Carlos Sgarbieri +1 more
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RETINOPATHY OF PREMATURITY AND MATERNAL AGE [PDF]
Retina, 2010 To determine the risk factors, especially maternal risk factors, associated with the development of retinopathy of prematurity (ROP) in premature babies.A matched case-control study involving premature patients was undertaken retrospectively. The case group consisted of premature babies with the subsequent development of ROP.
Wei‐Chi Wu +8 more
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What Is the Impact of Obesity-Related Comorbidities on the Risk of Premature Aging in Patients with Severe Obesity?: A Cross-Sectional Study [PDF]
MedicinaBackground and Objectives: The relationships between aging, chronic diseases, and obesity remain complex and poorly understood. This study aimed to investigate the impact of comorbidities on premature aging in individuals with severe obesity.
Alicja Dudek +9 more
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The epidemiology of premature aging and associated comorbidities
Clinical Interventions in Aging, 2013 Fabio Coppedè Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy Abstract: Hutchinson–Gilford Progeria Syndrome and Werner syndrome, also known as childhood- and adulthood ...
Coppedè F
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