Results 61 to 70 of about 2,392 (196)
Targeted therapy in nuclear medicine—current status and future prospects [PDF]
, 2017 In recent years, a number of new developments in targeted therapies using radiolabeled compounds have emerged. New developments and insights in radioiodine treatment of thyroid cancer, treatment of lymphoma and solid tumors with radiolabeled monoclonal ...
Bodei, L. +6 more
core
Cancer Medicine, Volume 15, Issue 1, January 2026.The debate in the field of cancer immunotherapy is being changed as nanotechnology breaks the obstacle of cancer immune evasion, target delivery, and systemic toxicity. Esthetically advanced methods that are discussed in this review are nanovaccine, nanoparticle‐enabled checkpoint barrier, cytokine delivery, and T‐cell modulation techniques that ...
Daniel Ejim Uti +7 more
wiley +1 more source
Pretargeted Radioimmunotherapy for Hematologic and Other Malignancies [PDF]
Cancer Biotherapy and Radiopharmaceuticals, 2010 Radioimmunotherapy (RIT) has emerged as one of the most promising treatment options, particularly for hematologic malignancies. However, this approach has generally been limited by a suboptimal therapeutic index (target-to-nontarget ratio) and an inability to deliver sufficient radiation doses to tumors selectively.
Roland B, Walter +2 more
openaire +2 more sources
Frontiers in Pharmacology, 2014 Although an increasing number of antibody conjugates are being used in the clinic, there remain many unmet needs in antibody targeting. Normal tissue background is one of the key issues that limits the therapeutic efficacy and detection sensitivity ...
Shuping eDou +5 more
doaj +1 more source
Pre-targeting and direct immunotargeting of liposomal drug carriers to ovarian carcinoma. [PDF]
PLoS ONE, 2012 BACKGROUND: Epidermal growth factor receptor (EGFR) is overexpressed in many solid tumor types, such as ovarian carcinoma. Immunoliposome based drug targeting has shown promising results in drug delivery to the tumors.
Julia Lehtinen +13 more
doaj +1 more source
The use of FD-filamentous bacteriophage for the in vivo imaging of cancer [PDF]
Dissertations, Academic -- University of Missouri--Columbia -- biochemistry (Medicine)."December 2006"Includes bibliographical references.Vita.The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the ...
Newton, Jessica R.
core +1 more source
Inverse electron demand Diels-Alder click chemistry for pretargeted PET imaging and radioimmunotherapy [PDF]
, 2021 This approach leverages the rapid, bio-orthogonal inverse electron demand Diels-Alder reaction between a radiolabeled tetrazine and a trans-cyclooctene-bearing antibody to enable pretargeted positron emission tomography imaging and endoradiotherapy in a ...
Carnazza, Kathryn E. +6 more
core +1 more source
ChemBioChem, Volume 27, Issue 1, January 2026.Radiopharmaceuticals enable precise cancer diagnosis and targeted therapy by combining radioactive isotopes with carrier molecules. This review summarizes advances from 2014 to 2025, emphasizing probe design, click chemistry, novel targets, and nanodelivery systems.
Mohd Sayeed Shaikh +7 more
wiley +1 more source
Pharmaceuticals, 2018 The inverse electron-demand Diels-Alder reaction between 1,2,4,5-tetrazine (Tz) and trans-cyclooct-2-ene (TCO) has gained increasing attraction among extensive studies on click chemistry due to its exceptionally fast reaction kinetics and high ...
Dominik Summer +7 more
doaj +1 more source
Hybrid Imaging Agents for Pretargeting Applications Based on Fusarinine C—Proof of Concept
Molecules, 2020 Hybrid imaging combining the beneficial properties of radioactivity and optical imaging within one imaging probe has gained increasing interest in radiopharmaceutical research.
Dominik Summer +9 more
doaj +1 more source