Results 231 to 240 of about 16,662 (259)
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Mini-Reviews in Medicinal Chemistry, 2008
Nucleic acids catalyse the conversion of alpha-helical prion protein to the beta-structured protein oligomers and amyloids structurally similar to the infectious isoform of protein. Simultaneously, the prion protein, similar to gene regulating proteins, bends, unwinds and condenses nucleic acid.
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Nucleic acids catalyse the conversion of alpha-helical prion protein to the beta-structured protein oligomers and amyloids structurally similar to the infectious isoform of protein. Simultaneously, the prion protein, similar to gene regulating proteins, bends, unwinds and condenses nucleic acid.
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Biochemical and Biophysical Research Communications, 2006
Amyloid plaques composed of proteinaceous aggregates are commonly found in brains affected by Alzheimer's disease and spongiform encephalopaties. A structural homology has been recently described for the Alzheimer's peptide Abeta1-28 and the segment of the prion protein Prp185-208.
Barbara, Klajnert +3 more
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Amyloid plaques composed of proteinaceous aggregates are commonly found in brains affected by Alzheimer's disease and spongiform encephalopaties. A structural homology has been recently described for the Alzheimer's peptide Abeta1-28 and the segment of the prion protein Prp185-208.
Barbara, Klajnert +3 more
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1994
"Prionlar, nükleik asitleri modifiye eden işlemlerle inaktive edilemeyen,temel ve gerekli komponent olan hücresel bir proteinin anormal bir izoformundanoluşan küçük, proteinden zengin, infeksiyöz partiküller" olaraktanımlanabilirler (42).Genetik bilginin nükleik asitlerden proteinlere dönüşümü , molekülerbiyolojinin temel doktrini olarak ...
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"Prionlar, nükleik asitleri modifiye eden işlemlerle inaktive edilemeyen,temel ve gerekli komponent olan hücresel bir proteinin anormal bir izoformundanoluşan küçük, proteinden zengin, infeksiyöz partiküller" olaraktanımlanabilirler (42).Genetik bilginin nükleik asitlerden proteinlere dönüşümü , molekülerbiyolojinin temel doktrini olarak ...
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Science, 2015
Converging paradigms in neurodegeneration Parkinson's disease and Alzheimer's disease are progressive neurodegenerative diseases with increasing prevalence in our aging populations. Recent evidence suggests that some of the molecular mechanisms involved in the pathology of these diseases have similarities to those observed in infectious prion
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Converging paradigms in neurodegeneration Parkinson's disease and Alzheimer's disease are progressive neurodegenerative diseases with increasing prevalence in our aging populations. Recent evidence suggests that some of the molecular mechanisms involved in the pathology of these diseases have similarities to those observed in infectious prion
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Critical Reviews in Eukaryotic Gene Expression, 2013
Prion diseases are fatal neurodegenerative disorders caused by altered forms of the prion protein (PrPC). It was reported that dysregulation of cellular Ca2+ homeostasis is recurrent in these diseases and that scrapie-infected cells exhibit Ca2+ perturbation via specific impairment of N-type calcium channels.
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Prion diseases are fatal neurodegenerative disorders caused by altered forms of the prion protein (PrPC). It was reported that dysregulation of cellular Ca2+ homeostasis is recurrent in these diseases and that scrapie-infected cells exhibit Ca2+ perturbation via specific impairment of N-type calcium channels.
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Prion‐related diseases and Creutzfeldt–Jakob disease (subacute spongiform encephalopathy)
European Journal of Neurology, 1996F. Boiler +4 more
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Future counselling of donors and recipients of blood products concerning prion‐related diseases
Vox Sanguinis, 2003Reesink, H. W. +22 more
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