Results 141 to 150 of about 3,816 (187)

The unfolded protein response in progeria arteries originates from non-endothelial cell types. [PDF]

Life Sci Alliance
Silva RA, Sarigol F, Karagöz GE, Osmanagic-Myers S, Foisner R.   +4 more
europepmc   +1 more source

Elevated SUN1 promotes migratory cell polarity defects through mechanically coupling microtubules to the nuclear lamina. [PDF]

Commun Biol
Li Y, Zhang Y, Chen M, Antoku S, Ding J, Huang K, Gundersen GG, Chang W.   +7 more
europepmc   +1 more source

A-type lamins anchor emerin at the inner nuclear membrane via two independent binding sites. [PDF]

J Biol Chem
Odell J, Nedza K, Lammerding J.
europepmc   +1 more source

Microhand Platform Equipped with Plate-Shaped End-Effectors Enables Precise Probing of Intracellular Structure Contribution to Whole-Cell Mechanical Properties. [PDF]

Micromachines (Basel)
Kawakami M, Kojima M, Ogura T, Kubo A, Arai T, Sakai S.   +5 more
europepmc   +1 more source

Progerin regulates actin cytoskeletal remodeling and inhibits EMT and metastasis in triple‑negative breast cancer cells. [PDF]

Int J Oncol
Huang X, Luo W, Liu W, Liu X, Chen W.
europepmc   +1 more source

Deep Profiling of the Aging Proteome Depicts Neuroinflammation, Synaptic Function, and Phosphorylation in an Accelerated Alzheimer's Disease Cell Model. [PDF]

Mol Cell Proteomics
Gentry E, Islam MT, Xue H, Cao K, Nemes P.   +4 more
europepmc   +1 more source

Pharmacologic activation of Δ133p53α reduces cellular senescence in progeria patients-derived cells. [PDF]

Aging Pathobiol Ther
Joruiz SM, Lissa D, Von Muhlinen N, Dranchak PK, Inglese J, Horikawa I, Harris CC.   +6 more
europepmc   +1 more source

A longevity-associated variant of the human BPIFB4 gene prevents diastolic dysfunction in progeria mice. [PDF]

Signal Transduct Target Ther
Qiu Y, Cattaneo M, Maciag A, Puca AA, Madeddu P.   +4 more
europepmc   +1 more source

Expression of progerin enhances disease-related endpoints in a tau seeding reporter cell system. [PDF]

Geroscience
Han ZZ, Kang SG, Gomez-Cardona E, Wohlgemuth S, Shmeit K, Arce L, Safar JG, Julien O, Westaway D.   +8 more
europepmc   +1 more source

Recurrent somatic mutation and progerin expression in early vascular aging of chronic kidney disease. [PDF]

Nat Aging
Revêchon G, Witasp A, Viceconte N, Helgadottir HT, Machtel P, Stefani F, Whisenant D, Sola-Carvajal A, McGuinness D, Abutaleb NO, Artiach G, Arzt EW, Soveri I, Babler A, Ziegler S, Kramann R, Bäck M, Thorell A, Truskey GA, Wennberg L, Shiels PG, Wernerson A, Stenvinkel P, Eriksson M.   +23 more
europepmc   +1 more source