Results 1 to 10 of about 1,264,892 (364)

Hypoxia-immune-related microenvironment prognostic signature for osteosarcoma

Frontiers in Cell and Developmental Biology, 2022
Introduction: Increasing evidences have shown that hypoxia and the immune microenvironment play vital roles in the development of osteosarcoma. However, reliable gene signatures based on the combination of hypoxia and the immune status for prognostic ...
Wenshuo Zhang, Pang Lyu, Darja Andreev, Yewei Jia, Fulin Zhang, Aline Bozec   +5 more
doaj   +4 more sources

Identification and validation of a hypoxia- and immune-related prognostic signature for pancreatic cancer [PDF]

Biochemistry and Biophysics Reports
Pancreatic cancer is a lethal disease with a poor prognosis. Immunity and hypoxia are critical characteristics of the tumor microenvironment and are closely associated with cancer prognosis. The present study aimed to identify a novel hypoxia- and immune-
Ganghua Yang, Jiawei Yu, Xuqi Li, Fandi Meng, Yong Wan, Zhengyang Lu, Zheng Wang, Qinhong Xu   +7 more
doaj   +2 more sources

A seven-gene prognostic signature predicts overall survival of patients with lung adenocarcinoma (LUAD)

Cancer Cell International, 2021
Background Lung adenocarcinoma (LUAD) is one of the most common types in the world with a high mortality rate. Despite advances in treatment strategies, the overall survival (OS) remains short.
Aisha Al-Dherasi, Qi-Tian Huang, Yuwei Liao, Sultan Al-Mosaib, Rulin Hua, Yichen Wang, Ying Yu, Yu Zhang, Xuehong Zhang, Chao Huang, Haithm Mousa, Dongcen Ge, Sufiyan Sufiyan, Wanting Bai, Ruimei Liu, Yanyan Shao, Yulong Li, Jingkai Zhang, Leming Shi, Dekang Lv, Zhiguang Li, Quentin Liu   +21 more
doaj   +2 more sources

Crosstalk of disulfidptosis-related subtypes, establishment of a prognostic signature and immune infiltration characteristics in bladder cancer based on a machine learning survival framework

Frontiers in Endocrinology, 2023
Background Bladder cancer (BLCA) is the most common malignancy of the urinary tract. On the other hand, disulfidptosis, a mechanism of disulfide stress-induced cell death, is closely associated with tumorigenesis and progression.
Songyun Zhao, Lanyu Wang, Wei Ding, Bicheng Ye, Chao Cheng, Jianfeng Shao, Jinhui Liu, Hongyi Zhou   +7 more
semanticscholar   +1 more source

Identification of a Novel Glycosyltransferase Prognostic Signature in Hepatocellular Carcinoma Based on LASSO Algorithm

Frontiers in Genetics, 2022
Although many prognostic models have been developed to help determine personalized prognoses and treatments, the predictive efficiency of these prognostic models in hepatocellular carcinoma (HCC), which is a highly heterogeneous malignancy, is less than ...
Zhiyang Zhou, Tao Wang, Yao Du, Junping Deng, Ge Gao, Jiangnan Zhang   +5 more
doaj   +1 more source

Ferroptosis-associated lncRNA prognostic signature predicts prognosis and immune response in clear cell renal cell carcinoma

Scientific Reports, 2023
Clear cell Renal Cell Carcinoma (ccRCC), the most deadly and life-threatening tumor in the urinary system, has a dismal prognosis and a high risk of metastasizing. Regulation of ferroptosis is a prospective therapeutic target to eradicate malignant cells.
Jiayi Lai, Shiqi Miao, Longke Ran
semanticscholar   +1 more source

Identification and validation of molecular subtype and prognostic signature for lung adenocarcinoma based on neutrophil extracellular traps

Pathology and Oncology Research, 2023
Background: Neutrophil Extracellular Traps (NETs) are fibrous networks made of DNA-histone complexes and proteins protruded from activated neutrophils.
Yanhua Zuo, G. Leng, Ping Leng
semanticscholar   +1 more source

Identification of a centrosome-related prognostic signature for breast cancer

Frontiers in Oncology, 2023
Background As the major microtubule organizing center in animal cells, the centrosome is implicated with human breast tumor in multiple ways, such as promotion of tumor cell immune evasion.
Zhou Fang, Zhijie Gao, Xin Yu, Shengrong Sun, F. Yao   +4 more
semanticscholar   +1 more source

Construction of a Lactate-Related Prognostic Signature for Predicting Prognosis, Tumor Microenvironment, and Immune Response in Kidney Renal Clear Cell Carcinoma

Frontiers in Immunology, 2022
Kidney renal clear cell carcinoma (KIRC) is one of the most prevalent primary malignancies with high heterogeneity in the urological system. Growing evidence implies that lactate is a significant carbon source for cell metabolism and plays a vital role ...
Zhuolun Sun, W. Tao, Xudong Guo, Changying Jing, Ming-xiao Zhang, Zhenqing Wang, F. Kong, Ning Suo, Shaobo Jiang, Hanbo Wang   +9 more
semanticscholar   +1 more source

Identification of a Costimulatory Molecule-Related Signature for Predicting Prognostic Risk in Prostate Cancer

Frontiers in Genetics, 2021
Costimulatory molecules have been proven to enhance antitumor immune responses, but their roles in prostate cancer (PCa) remain unexplored. In this study, we aimed to explore the gene expression profiles of costimulatory molecule genes in PCa and ...
Shengdong Ge, Shengdong Ge, Shengdong Ge, Xiaoliang Hua, Xiaoliang Hua, Xiaoliang Hua, Juan Chen, Haibing Xiao, Haibing Xiao, Haibing Xiao, Li Zhang, Li Zhang, Li Zhang, Jun Zhou, Jun Zhou, Jun Zhou, Chaozhao Liang, Chaozhao Liang, Chaozhao Liang, Sheng Tai, Sheng Tai, Sheng Tai   +21 more
doaj   +1 more source