Results 91 to 100 of about 2,442 (188)
A Rare NPHS2 Mutation (E130K) in Hereditary Steroid‐Resistant Nephrotic Syndrome: A Case Report
Hereditary steroid‐resistant nephrotic syndrome (HSRNS) due to mutations in the NPHS2 gene (encoding podocin) is a rare genetic condition that typically presents in childhood. We report a case of a 2‐year‐and‐8‐month‐old male, the seventh child of consanguineous parents, who presented with recurrent fever, febrile tonic‐clonic seizures, and periorbital
Ramzi Hmedan Mujahed +7 more
wiley +1 more source
Characterisation of detergent-insoluble membranes in pollen tubes of Nicotiana tabacum (L.)
Pollen tubes are the vehicle for sperm cell delivery to the embryo sac during fertilisation of Angiosperms. They provide an intriguing model for unravelling mechanisms of growing to extremes.
Alessandra Moscatelli +9 more
doaj +1 more source
Diabetic nephropathy (DN), a predominant cause of end‐stage renal disease (ESRD), is primarily driven bfigolic disturbances and mitochondrial dysfunction. Apolipoprotein M (ApoM), a protein associated with high‐density lipoprotein (HDL), is notably downregulated in DN and is correlated with a decline in renal function.
Tianlei Chen, Min Yang, Hannah Wesley
wiley +1 more source
The IgM antigen receptor of B lymphocytes is associated with prohibitin and a prohibitin-related protein. [PDF]
The two major classes of antigen receptors on murine B lymphocytes, mIgM and mIgD, are both contained in a complex with two additional molecules, Ig-alpha and Ig-beta, which permit signal transduction. Accordingly, early biochemical events after antigen binding to either receptor are similar; biological effects, however, are different.
M, Terashima +6 more
openaire +2 more sources
The SBT6.1 subtilase processes the GOLVEN1 peptide controlling cell elongation [PDF]
Maturation of GLV signaling peptides requires two SBT6 subtilases. SBT6 proteolytic activity is further regulated by the Serpin1 inhibitor, implying a complex network that controls cell elongation in Arabidopsis.The GOLVEN (GLV) gene family encode small ...
Beeckman, Tom +11 more
core +4 more sources
Characterized by its capacity to induce organ failure, sepsis constitutes a life‐threatening pathological state with high incidence and mortality rates. Current treatments primarily focus on antimicrobial therapy and organ support, lacking direct interventions targeting the restoration of cellular or organelle function.
Xiangxin Liao +5 more
wiley +1 more source
Prohibitin: an unexpected role in sex dimorphic functions [PDF]
Sex differences are known to exist in adipose and immune functions in the body, and sex steroid hormones are known to be involved in sexually dimorphic biological and pathological processes related to adipose-immune interaction. However, our knowledge of proteins that mediate such differences is poor. Two novel obese mice models, Mito-Ob and m-Mito-Ob,
Nguyen, K. H +2 more
openaire +2 more sources
Resonant Recognition Model Study for Interactions between SARS CoV 2 and Human Proteins
Este estudio se dedicó al análisis mediante el Modelo de Reconocimiento Resonante (RRM) de las proteínas del SARS-CoV-2 y su posible interacción con otras proteínas humanas, específicamente, fueron analizadas las replicasas de SARS CoV y las ...
Susana Margarita Montesino Castillo +2 more
doaj
Decorin transfection induces proteomic and phenotypic modulation in breast cancer cells 8701-BC [PDF]
Decorin is a prototype member of the small leucine-rich proteoglycan family widely distributed in the extracellular matrices of many connective tissues, where it has been shown to play multiple important roles in the matrix assembly process, as well as ...
Cancemi P +10 more
core +1 more source
Abstract The qualified presumption of safety (QPS) process was developed to provide a harmonised safety assessment approach to support EFSA Scientific Panels and Units. The QPS approach assesses the taxonomic identity, body of relevant knowledge and safety of microorganisms intentionally added to the food and feed chain.
EFSA Panel on Biological Hazards (BIOHAZ) +28 more
wiley +1 more source

