Results 91 to 100 of about 2,442 (188)

A Rare NPHS2 Mutation (E130K) in Hereditary Steroid‐Resistant Nephrotic Syndrome: A Case Report

open access: yesCase Reports in Nephrology, Volume 2026, Issue 1, 2026.
Hereditary steroid‐resistant nephrotic syndrome (HSRNS) due to mutations in the NPHS2 gene (encoding podocin) is a rare genetic condition that typically presents in childhood. We report a case of a 2‐year‐and‐8‐month‐old male, the seventh child of consanguineous parents, who presented with recurrent fever, febrile tonic‐clonic seizures, and periorbital
Ramzi Hmedan Mujahed   +7 more
wiley   +1 more source

Characterisation of detergent-insoluble membranes in pollen tubes of Nicotiana tabacum (L.)

open access: yesBiology Open, 2015
Pollen tubes are the vehicle for sperm cell delivery to the embryo sac during fertilisation of Angiosperms. They provide an intriguing model for unravelling mechanisms of growing to extremes.
Alessandra Moscatelli   +9 more
doaj   +1 more source

Focusing on the Apolipoprotein M–Mitophagy Axis: A Mechanism for Renal Protection in Diabetic Nephropathy

open access: yesJournal of Diabetes Research, Volume 2026, Issue 1, 2026.
Diabetic nephropathy (DN), a predominant cause of end‐stage renal disease (ESRD), is primarily driven bfigolic disturbances and mitochondrial dysfunction. Apolipoprotein M (ApoM), a protein associated with high‐density lipoprotein (HDL), is notably downregulated in DN and is correlated with a decline in renal function.
Tianlei Chen, Min Yang, Hannah Wesley
wiley   +1 more source

The IgM antigen receptor of B lymphocytes is associated with prohibitin and a prohibitin-related protein. [PDF]

open access: yesThe EMBO Journal, 1994
The two major classes of antigen receptors on murine B lymphocytes, mIgM and mIgD, are both contained in a complex with two additional molecules, Ig-alpha and Ig-beta, which permit signal transduction. Accordingly, early biochemical events after antigen binding to either receptor are similar; biological effects, however, are different.
M, Terashima   +6 more
openaire   +2 more sources

The SBT6.1 subtilase processes the GOLVEN1 peptide controlling cell elongation [PDF]

open access: yes, 2016
Maturation of GLV signaling peptides requires two SBT6 subtilases. SBT6 proteolytic activity is further regulated by the Serpin1 inhibitor, implying a complex network that controls cell elongation in Arabidopsis.The GOLVEN (GLV) gene family encode small ...
Beeckman, Tom   +11 more
core   +4 more sources

Bidirectional Regulation of NLRP3 Inflammasome and Mitochondrial Quality Control in Sepsis: Mechanisms and Therapeutic Implications

open access: yesMediators of Inflammation, Volume 2026, Issue 1, 2026.
Characterized by its capacity to induce organ failure, sepsis constitutes a life‐threatening pathological state with high incidence and mortality rates. Current treatments primarily focus on antimicrobial therapy and organ support, lacking direct interventions targeting the restoration of cellular or organelle function.
Xiangxin Liao   +5 more
wiley   +1 more source

Prohibitin: an unexpected role in sex dimorphic functions [PDF]

open access: yesBiology of Sex Differences, 2016
Sex differences are known to exist in adipose and immune functions in the body, and sex steroid hormones are known to be involved in sexually dimorphic biological and pathological processes related to adipose-immune interaction. However, our knowledge of proteins that mediate such differences is poor. Two novel obese mice models, Mito-Ob and m-Mito-Ob,
Nguyen, K. H   +2 more
openaire   +2 more sources

Resonant Recognition Model Study for Interactions between SARS CoV 2 and Human Proteins

open access: yesRevista Cubana de Informática Médica, 2020
Este estudio se dedicó al análisis mediante el  Modelo de Reconocimiento Resonante (RRM) de las proteínas del SARS-CoV-2 y su posible interacción con otras proteínas humanas, específicamente, fueron analizadas las replicasas de SARS CoV y las ...
Susana Margarita Montesino Castillo   +2 more
doaj  

Decorin transfection induces proteomic and phenotypic modulation in breast cancer cells 8701-BC [PDF]

open access: yes, 2008
Decorin is a prototype member of the small leucine-rich proteoglycan family widely distributed in the extracellular matrices of many connective tissues, where it has been shown to play multiple important roles in the matrix assembly process, as well as ...
Cancemi P   +10 more
core   +1 more source

Update of the list of qualified presumption of safety (QPS) recommended microbiological agents intentionally added to food or feed as notified to EFSA 23: Suitability of taxonomic units notified to EFSA until September 2025

open access: yesEFSA Journal, Volume 24, Issue 1, January 2026.
Abstract The qualified presumption of safety (QPS) process was developed to provide a harmonised safety assessment approach to support EFSA Scientific Panels and Units. The QPS approach assesses the taxonomic identity, body of relevant knowledge and safety of microorganisms intentionally added to the food and feed chain.
EFSA Panel on Biological Hazards (BIOHAZ)   +28 more
wiley   +1 more source

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