Results 91 to 100 of about 2,450 (184)

Characterisation of detergent-insoluble membranes in pollen tubes of Nicotiana tabacum (L.)

open access: yesBiology Open, 2015
Pollen tubes are the vehicle for sperm cell delivery to the embryo sac during fertilisation of Angiosperms. They provide an intriguing model for unravelling mechanisms of growing to extremes.
Alessandra Moscatelli   +9 more
doaj   +1 more source

Alcohol‐Related Liver Disease and Metabolic Dysfunction‐Associated Steatotic Liver Disease: Molecular Pathogenesis and Therapeutic Interventions

open access: yesMedComm, Volume 6, Issue 12, December 2025.
Alcohol‐related (ALD) and metabolic dysfunction‐associated (MASLD) steatotic liver disease, while initiated by distinct etiologies (ethanol vs. metabolic stress), converge on shared core pathogenic pathways that drive progression. These include dysregulated lipid metabolism, programmed cell death, cellular senescence, gut dysbiosis, and immune ...
Yupin Tan   +3 more
wiley   +1 more source

Imaging Findings of Paratesticular Adenomatoid Tumor

open access: yesClinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT Paratesticular adenomatoid tumors are benign growths usually found near the epididymis. They often show no symptoms and appear as hyperechoic masses on ultrasound. Magnetic resonance imaging helps in difficult cases. Surgical removal is curative with minimal recurrence risk.
Wenqin Liu   +3 more
wiley   +1 more source

The IgM antigen receptor of B lymphocytes is associated with prohibitin and a prohibitin-related protein. [PDF]

open access: yesThe EMBO Journal, 1994
The two major classes of antigen receptors on murine B lymphocytes, mIgM and mIgD, are both contained in a complex with two additional molecules, Ig-alpha and Ig-beta, which permit signal transduction. Accordingly, early biochemical events after antigen binding to either receptor are similar; biological effects, however, are different.
M, Terashima   +6 more
openaire   +2 more sources

Oxidative phosphorylation at the crossroads of cancer: Metabolic orchestration, stromal collusion, and emerging therapeutic horizons

open access: yesInterdisciplinary Medicine, Volume 3, Issue 6, November 2025.
Although most cancer cells rely on aerobic glycolysis, Oxidative phosphorylation (OXPHOS) remains essential for their survival, proliferation, and metastasis. With the emergence of OXPHOS‐targeted drugs, its therapeutic potential is becoming increasingly evident.
Keke Chen   +5 more
wiley   +1 more source

Prohibitin: an unexpected role in sex dimorphic functions [PDF]

open access: yesBiology of Sex Differences, 2016
Sex differences are known to exist in adipose and immune functions in the body, and sex steroid hormones are known to be involved in sexually dimorphic biological and pathological processes related to adipose-immune interaction. However, our knowledge of proteins that mediate such differences is poor. Two novel obese mice models, Mito-Ob and m-Mito-Ob,
Nguyen, K. H   +2 more
openaire   +2 more sources

Resonant Recognition Model Study for Interactions between SARS CoV 2 and Human Proteins

open access: yesRevista Cubana de Informática Médica, 2020
Este estudio se dedicó al análisis mediante el  Modelo de Reconocimiento Resonante (RRM) de las proteínas del SARS-CoV-2 y su posible interacción con otras proteínas humanas, específicamente, fueron analizadas las replicasas de SARS CoV y las ...
Susana Margarita Montesino Castillo   +2 more
doaj  

The SBT6.1 subtilase processes the GOLVEN1 peptide controlling cell elongation [PDF]

open access: yes, 2016
Maturation of GLV signaling peptides requires two SBT6 subtilases. SBT6 proteolytic activity is further regulated by the Serpin1 inhibitor, implying a complex network that controls cell elongation in Arabidopsis.The GOLVEN (GLV) gene family encode small ...
Beeckman, Tom   +11 more
core   +4 more sources

Synthesized Depside Molecules Suppress the Progression of Colorectal Cancer by Binding VDAC1/PHB/MMP9 Being at the Crossroads of Stemness, Motility, Apoptosis, and Metabolism

open access: yesMedComm, Volume 6, Issue 11, November 2025.
This study suggests that newly synthesized depside compounds suppress the progression of colorectal cancer by directly targeting VDAC1/PHB/MMP9. Especially, SB4 demonstrated significant bioavailability and successfully suppressed the tumor growth. ABSTRACT Lichen secondary metabolites have shown potential in cancer therapy, but strategies to enhance ...
Mücahit Varlı   +7 more
wiley   +1 more source

PHB3 Maintains Root Stem Cell Niche Identity through ROS-Responsive AP2/ERF Transcription Factors in Arabidopsis

open access: yesCell Reports, 2018
Summary: The root stem cell niche, which is composed of four mitotically inactive quiescent center (QC) cells and the surrounding actively divided stem cells in Arabidopsis, is critical for growth and root development.
Xiangpei Kong   +13 more
doaj   +1 more source

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