Results 61 to 70 of about 11,689 (228)
Chamomile (Matricaria chamomilla) extract significantly reduced oocyst shedding and intestinal lesions in immunosuppressed mice infected with Cryptosporidium parvum, while enhancing antioxidant defences (GPx, TAC). These findings suggest chamomile as a promising phytotherapeutic agent for cryptosporidiosis. ABSTRACT Background Cryptosporidiosis, caused
Kousha Kiani +3 more
wiley +1 more source
Background and Objectives: Due to adverse effects of pentavalent antimonial treatment of visceral leishmaniasis using herbal medicines has received a lot of attention.
Mohaddeseh Abouhosseini Tabari +5 more
doaj
Detergent-resistant membranes (DRMs) from Leishmania (Viannia) braziliensis promastigotes, insoluble in 1% Triton X-100 at 4°C, were fractionated by sucrose density gradient ultracentrifugation.
Kelly A.G. Yoneyama +4 more
doaj +1 more source
ABSTRACT Trypanosoma cruzi undergoes heat stress during its life cycle. In this study, we performed a transcriptomic analysis of the heat shock response in epimastigotes from different T. cruzi strains. In both clone CL Brener and the Y strain, very few to no statistically significant variations were observed in the transcriptome at 37°C, whereas ...
Thayane Bottaro +3 more
wiley +1 more source
Cytotoxicity of acridine compounds for Leishmania promastigotes in vitro [PDF]
The effect of mammalian and bacterial topoisomerase II inhibitors on Leishmania promastigotes was studied in vitro. Parasites were incubated with drugs, and cytotoxicity was assessed on the basis of the loss of flagellar motility and cell lysis after 48 h.
K A, Werbovetz +3 more
openaire +2 more sources
A novel pyridine–thiazole derivative, Compound 8, exhibited potent dual antitrypanosomatid activity. It demonstrated remarkable in vitro efficacy against Trypanosoma cruzi (IC50 = 1.0 µM) and L. amazonensis (IC50 = 3.9 µM). Molecular docking studies suggested interactions with heme and multiple molecular targets.
Anderson José Firmino Santos da Silva +10 more
wiley +1 more source
Complete L. mexicana culture and sand fly derived promastigote cell data.
Complete L. mexicana culture and sand fly derived promastigote cell data.
Molly Hair (18071631) +7 more
core +1 more source
Damage to the promastigote surface membrane visualised by flow cytometry.
PI-signal in flow cytometry, after incubation with chemokines, positive cells as a percentage of gated cells (A). Plots showing side scatter (y-axis) and forward scatter (x-axis) of untreated promastigote cells (B), and cells treated with Amphotericin B (
Matthias Mörgelin (109607) +5 more
core +1 more source
Study on the Occurrence of Genetic Exchange Among Parasites of the Leishmania mexicana Complex
In Leishmania, genetic exchange has been experimentally demonstrated to occur in the sand fly vector and in promastigote axenic cultures through a meiotic-like process.
Roman Telittchenko, Albert Descoteaux
doaj +1 more source
Stage-specific pathways of Leishmania infantum chagasi entry and phagosome maturation in macrophages. [PDF]
The life stages of Leishmania spp. include the infectious promastigote and the replicative intracellular amastigote. Each stage is phagocytosed by macrophages during the parasite life cycle.
Nilda E Rodríguez +3 more
doaj +1 more source

