Results 111 to 120 of about 3,425 (209)
, 1990 Highly purified recombinant human prorenin, labeled with 125I (125I-prorenin), was intravenously given to monkeys to examine the possible in vivo conversion of this prorenin to renin.
S. Kim +5 more
core +1 more source
Extrarenal production and activation of human plasma prorenin: the evidence after venous occlusion
, 1989 Venous occlusion of the left arm in consenting men was induced for 10 or 20 min to stimulate local fibrinolytic and other proteases, thereby favouring the conversion of prorenin to renin.
Daniel H. Osmond +2 more
core +1 more source
Ang II potentiates prorenin-induced TNFα production in microglia.
, 2014 Mouse N-9 cells were pretreated with control media (DMEM) or Ang II (100 nmol/L) for 12 h, followed by treatment with DMEM or prorenin (20 nmol/L) for 6 hr. Next, TNFα positive cells were analyzed by flow cytometry.
Xiao Z. Shen (642848) +8 more
core +1 more source
Characterization of renin mRNA expression and enzyme activity in rat and mouse mesangial cells
Brazilian Journal of Medical and Biological Research, 2002 Renin is an enzyme involved in the stepwise generation of angiotensin II. Juxtaglomerular cells are the main source of plasma renin, but renin activity has been detected in other cell types. In the present study we evaluated the presence of renin mRNA in
Andrade A.Q. +3 more
doaj
The synthesis, secretion and uptake of prorenin in human amnion
Very high concentrations of prorenin protein occur in human amniotic fluid and amnion. The source of amniotic fluid prorenin is likely the decidua, as it has the highest levels of prorenin mRNA (REN). Conversely, REN mRNA levels in amnion and chorion are
Yu Wang (12152) +2 more
core
Recombinant human prorenin expression in baculovirus infected cells
, 1997 Renin is an aspartyl proteinase implicated in the regulation of blood pressure and fluid balance. As many other secreted enzymes, it is synthesized as a precursor, prorenin, that is cleaved by a processing enzyme during its migration through the cell ...
Vendette, Marc.
core
Renin and prorenin disappearance in humans post-nephrectomy: evidence for binding?
, 2008 To study the distribution of kidney-derived renin-angiotensin system (RAS) components in humans, we monitored the decline in plasma prorenin, renin, angiotensin (Ang) I and Ang II post-nephrectomy.
de Bruyn, JHB +3 more
core +1 more source
Prorenin is present in human red blood cells
, 1991 We looked for the presence of prorenin in erythrocytes from normal subjects (n = 8), hypertensive patients (n = 8), and pregnant women (n = 8). Angiotensin I generation was measured at 37 °C, pH 5.7, in the presence of homologous substrate (1400 ng/mL ...
A. Pazzola +12 more
core +1 more source
Plasma prorenin as an early marker of microvascular disease in patients with diabetes mellitus
, 1992 To test the hypothesis that a high plasma prorenin can be used as an early marker of microvascular complications in patients with diabetes mellitus plasma prorenin was measured in 44 patients with urinary albumin excretion between 30 and 300 mg/24 h ...
Blankestijn, P. J. +10 more
core +2 more sources
Prorenin and the (pro)renin receptor--an update [PDF]
Nephrology Dialysis Transplantation, 2007 Danser, Jan +2 more
openaire +3 more sources