Results 21 to 30 of about 3,781 (209)
Biomedicines, 2021 The gut microbiome is closely related to gut metabolic functions, and the gut microbiome and host metabolic functions affect each other. Clostridium butyricum MIYAIRI 588 (CBM 588) upregulates protectin D1 production in host colon tissue following G ...
Tadashi Ariyoshi +9 more
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Resolvins and Protectins in Inflammation Resolution [PDF]
Chemical Reviews, 2011 The critical role of inflammatory processes in health and disease has long been recognized,1 yet the detailed molecular mechanisms and biological events that regulate the progression and resolution of inflammation remain of interest. A number of recent investigations have provided strong evidence that the resolution of inflammation is not a passive ...
Charles N, Serhan, Nicos A, Petasis
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Frontiers in Immunology, 2021 Viral pneumonias are a major cause of morbidity and mortality, owing in part to dysregulated excessive lung inflammation, and therapies to modulate host responses to viral lung injury are urgently needed.
Katherine H. Walker +5 more
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Protectins: Their biosynthesis, metabolism and structure-functions
Biochemical Pharmacology, 2022 Several lipoxygenase enzymes and cyclooxygenase-2 stereoselectively convert the polyunsaturated fatty acids arachidonic acid, eicosapentaenoic acid, docosahexaenoic acid, and n-3 docosapentaenoic acid into numerous oxygenated products. Biosynthetic pathway studies have shown, during the resolution phase of acute inflammation, that distinct families of ...
Hansen, Trond Vidar, Serhan, Charles N.
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Frontiers in Psychiatry, 2020 Inflammation has been identified as one of the main pathophysiological mechanisms underlying neuropsychiatric and neurodegenerative disorders. Despite the role of inflammation in those conditions, there is still a lack of effective anti-inflammatory ...
Juliette Giacobbe +4 more
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Aurin tricarboxylic acid protects against red blood cell hemolysis in patients with paroxysmal nocturnal hemoglobinemia. [PDF]
PLoS ONE, 2014 OBJECTIVES: Paroxysmal nocturnal hemoglobinemia (PNH) is a rare but serious condition characterized by complement-mediated red blood cell (RBC) hemolysis and episodic thrombotic attack.
Moonhee Lee +3 more
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Differential Mobility Separation of Leukotrienes and Protectins [PDF]
Analytical Chemistry, 2015 Differential mobility spectrometry (DMS) is capable of separating stereoisomeric molecular ions based on their mobility in an oscillating electrical field with an asymmetric waveform. Thus, it is an "orthogonal" technique to chromatography and (tandem) mass spectrometry.
Jónasdóttir, Hulda +7 more
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Docosahexaenoic acid, protectins and dry eye [PDF]
Current Opinion in Clinical Nutrition and Metabolic Care, 2011 To report recent data on the potential role of omega-3 fatty acids, in particular docosahexaenoic acid and its derivatives, in the treatment of dry eye syndrome.Dietary supplementation with polyunsaturated fatty acids yields positive results in the improvement of dry eye signs and symptoms.
Maria S, Cortina, Haydee E P, Bazan
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Resolvins and protectins: mediating solutions to inflammation [PDF]
British Journal of Pharmacology, 2009 Resolution of inflammation has historically been viewed as a passive process, occurring as a result of the withdrawal of pro‐inflammatory signals, including lipid mediators such as leukotrienes and prostaglandins. Thus, most anti‐inflammatory drugs have traditionally targeted primarily mediator pathways that are engaged at the onset of inflammation ...
Payal, Kohli, Bruce D, Levy
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Molecules, 2014 The omega-3 polyunsaturated fatty acids (ω-3 PUFAs) docosahexaenoic acid (DHA) and/or eicosapentaenoic acid (EPA) protect against diabetic nephropathy by inhibiting inflammation.
Masanori Katakura +8 more
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