Docosahexaenoic acid, protectins and dry eye [PDF]
To report recent data on the potential role of omega-3 fatty acids, in particular docosahexaenoic acid and its derivatives, in the treatment of dry eye syndrome.Dietary supplementation with polyunsaturated fatty acids yields positive results in the improvement of dry eye signs and symptoms.
Maria S, Cortina, Haydee E P, Bazan
openaire +2 more sources
Resolvins and protectins: mediating solutions to inflammation [PDF]
Resolution of inflammation has historically been viewed as a passive process, occurring as a result of the withdrawal of pro‐inflammatory signals, including lipid mediators such as leukotrienes and prostaglandins. Thus, most anti‐inflammatory drugs have traditionally targeted primarily mediator pathways that are engaged at the onset of inflammation ...
Payal, Kohli, Bruce D, Levy
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Effect of protectin on IMR-32 cells. [PDF]
IMR-32 cells were exposed to different doses (1, 5, 10 ng/ml) of protectin (19,20-DiHDPA, 10(S),17(S)-DiHDoHE) and incubated for 24 hrs. At the end of treatment period, cell viability was measured by MTT assay. All values are expressed as mean ± standard
Arul M. Mani (678608) +5 more
core +1 more source
Protectin and resolvin gut inflammation [PDF]
Inflammation Even when laced with syrup, cod-liver oil is disgusting, but it is an important source of omega-3-docosapentaenoic fatty acid (DPA). After being swallowed, DPA is converted into specialized proresolving lipid mediators (SPMs), including protectin and resolvin.
openaire +2 more sources
Anti-inflammatory and anti-virus potential of poxytrins, especially protectin DX [PDF]
International audiencePoxytrins (Pufa Oxygenated Trienes) are dihydroxy derivatives from polyunsaturated fatty acids (PUFA) with adjacent hydroxyl groups to a conjugated triene having the specific E,Z,E geometry. They are made by the double action of one
Michel Guichardant +5 more
core +1 more source
Effect of protectin on bleomycin induced cytotoxicity in IMR-32 cells. [PDF]
(A) Effect of pre-treatment with different doses (1, 5, 10 ng/ml) of protectin (19,20-DiHDPA, 10(S),17(S)-DiHDoHE) on bleomycin (60 µg/ml) induced cytotoxicity to IMR-32 cells.
Arul M. Mani (678608) +5 more
core +1 more source
Rapid Metabolization of Protectin D1 by β‑Oxidation of Its Polar Head Chain [PDF]
Protectin D1 [neuroprotectin D1 (NPD1), PD1] has been proposed to play a key role in the resolution of inflammation. Aside from its ω-monohydroxylated metabolite, little has been reported on its metabolic fate. Upon NPD1 incubation in HepG2 cells, liquid
Carola Buccellati (283007) +9 more
core +5 more sources
Virulence and antibiotic resistance profile of avian Escherichia coli strains isolated from colibacillosis lesions in central of Algeria [PDF]
Background and Aim: Avian pathogenic Escherichia coli cause extensive mortality in poultry flocks, leading to extensive economic losses. To date, in Algeria, little information has been available on virulence potential and antibiotics resistance of avian
Nacima Meguenni +5 more
doaj +1 more source
The complement-inhibiting protein, Protectin (CD59 antigen), is present and functionally active on glomerular epithelial cells [PDF]
SUMMARY Protectin (CDS9 antigen) is a 20-kD phosphatidyl-inositol-linked membrane protein that inhibits formation of the membrane attack complex (MAC) of complement on homologous cells.
Griffiths, David Francis Rees +15 more
core +1 more source
Molecular Circuits of Resolution: Formation and Actions of Resolvins and Protectins [PDF]
Abstract The cellular events underlying the resolution of acute inflammation are not known in molecular terms. To identify anti-inflammatory and proresolving circuits, we investigated the temporal and differential changes in self-resolving murine exudates using mass spectrometry-based proteomics and lipidomics.
Gerard L, Bannenberg +7 more
openaire +3 more sources

