Results 41 to 50 of about 3,781 (209)
Frontiers in Immunology, 2012 Acute inflammation and its resolution are essential processes for tissue protection and homeostasis. Once thought to be a passive process, the resolution of inflammation is now shown to involve active biochemical programs that enable inflamed tissues to ...
Yosuke eIsobe +3 more
doaj +1 more source
Frontiers in PharmacologySepsis-associated lung injury (SALI) is a critical condition with high mortality. Current therapies are limited, necessitating novel approaches. This review highlights the potential of exogenous Specialized Pro-resolving Mediators (SPMs), including ...
Jiwei Shen +26 more
doaj +1 more source
Major Structure–Activity Relationships of Resolvins, Protectins, Maresins and Their Analogues
Future Medicinal Chemistry, 2022 Resolvins, protectins and maresins are a series of polyunsaturated fatty acid-derived molecules which play important roles in the resolution of inflammation. They are termed specialized proresolving mediators and facilitate a return to homeostasis following an inflammatory response.
Kevin Daly +2 more
openaire +3 more sources
Effect of protectin on IMR-32 cells.
, 2014 IMR-32 cells were exposed to different doses (1, 5, 10 ng/ml) of protectin (19,20-DiHDPA, 10(S),17(S)-DiHDoHE) and incubated for 24 hrs. At the end of treatment period, cell viability was measured by MTT assay. All values are expressed as mean ± standard
Arul M. Mani (678608) +5 more
core +1 more source
Optimizing complement-activating antibody-based cancer immunotherapy: a feasible strategy?
Journal of Translational Medicine, 2004 Passive immunotherapy with monoclonal antibodies (mAb) targeted to specific tumor-associated antigens is amongst the most rapidly expanding approaches to biological therapy of cancer.
Maio Michele +2 more
doaj +1 more source
iMetaOmics, EarlyView.Advances in sequencing and mass spectrometry have propelled life sciences into the multi‐omics era. Metabolomics and microbiomics are widely applied across various research fields, yet massive data analysis faces challenges like limited tool functionality and high technical barriers.
Jianhua Zhao +16 more
wiley +1 more source
Anti-inflammatory and anti-virus potential of poxytrins, especially protectin DX
, 2020 International audiencePoxytrins (Pufa Oxygenated Trienes) are dihydroxy derivatives from polyunsaturated fatty acids (PUFA) with adjacent hydroxyl groups to a conjugated triene having the specific E,Z,E geometry. They are made by the double action of one
Michel Guichardant +5 more
core +1 more source
Protectin DX Relieve Hyperoxia‐induced Lung Injury by Protecting Pulmonary Endothelial Glycocalyx
Journal of Inflammation Research, 2023 Zhongjie Liang,1,2 Huilin Yue,1 Congcong Xu,1 Qian Wang,3 Shengwei Jin2,3 1Department of Neonatology, The Second Affiliated Hospital, Yuying Children’s Hospital of Wenzhou Medical University, Zhejiang, People’s Republic of China; 2Department of ...
Liang Z, Yue H, Xu C, Wang Q, Jin S
doaj
Effect of protectin on bleomycin induced cytotoxicity in IMR-32 cells.
, 2014 (A) Effect of pre-treatment with different doses (1, 5, 10 ng/ml) of protectin (19,20-DiHDPA, 10(S),17(S)-DiHDoHE) on bleomycin (60 µg/ml) induced cytotoxicity to IMR-32 cells.
Arul M. Mani (678608) +5 more
core +1 more source
Rapid Metabolization of Protectin D1 by β‑Oxidation of Its Polar Head Chain
, 2019 Protectin D1 [neuroprotectin D1 (NPD1), PD1] has been proposed to play a key role in the resolution of inflammation. Aside from its ω-monohydroxylated metabolite, little has been reported on its metabolic fate. Upon NPD1 incubation in HepG2 cells, liquid
Carola Buccellati (283007) +9 more
core +3 more sources