Extracellular domain of type I receptor for transforming growth factor-β: molecular modelling using protectin (CD59) as a template [PDF]
, 1995 We have observed that the extracellular domain of TβRI and protectin (CD59), an inhibitor of the membrane attack complex of complement, share structural features, a distinct spacing of ten cysteines and a C-terminal ‘Cys-box’.
Tissari, Jorma +8 more
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Frontiers in Immunology, 2012 Unresolved inflammation is associated with several widely occurring diseases such as arthritis, periodontal diseases, cancer, and atherosclerosis.
Charles N Serhan, Antonio eRecchiuti
doaj +1 more source
Acquired resistance of Escherichia coli to complement lysis by binding of glycophosphoinositol-anchored protectin (CD59) [PDF]
, 1998 Protectin (CD59) is a glycophosphoinsitol (GPI)-anchored defender of human cells against lysis by the membrane attack complex of complement. In this study, we examined whether protectin released from human cell membranes can incorporate into the surface ...
Jarvis, Gary A. +3 more
core +2 more sources
Protection of gingival epithelium against complement-mediated damage by strong expression of the membrane attack complex inhibitor protectin (CD59) [PDF]
, 1996 Adult periodontitis (AP) is a chronic inflammatory disease of the tooth-supporting apparatus. Activation products of the inflammation-inducing complement system have been detected in the gingival crevicular fluid at the site of gingival inflammation.
Meri, S. +1 more
core +4 more sources
Synthesis, Structural Confirmation, and Biosynthesis of 22-OH-PD1n-3 DPA
Molecules, 2019 PD1n-3 DPA belongs to the protectin family of specialized pro-resolving lipid mediators. The protectins are endogenously formed mediators that display potent anti-inflammatory properties and pro-resolving bioactivities and have attracted interest in drug
Jannicke Irina Nesman +5 more
doaj +1 more source
Review of the Screening Tool for Child Abuse by Health Care Provider [PDF]
Pediatric Emergency Medicine Journal, 2015 The recent report regarding the death of children due to child abuse brought on an implementation of an Act on special cases concerning the punishment, etc. of crimes of child abuse in September 2014. According to the report in 2013 by the National Child
Jin Hee Jung, Young Ho Kwak
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Docosahexaenoic acid, protectin synthesis: relevance against atherothrombogenesis [PDF]
Proceedings of the Nutrition Society, 2013 DHA is an abundant nutrient from marine lipids: its specific biological effects have been investigated in human volunteers, taking into consideration the dose effects. We report herein that, at dosages below 1 g/d, DHA proved to be effective in lowering blood platelet function and exhibited an ‘antioxidant’ effect.
Michel, Lagarde +6 more
openaire +3 more sources
Protectin DX as a therapeutic strategy against frailty in mice
GeroScience, 2023 AbstractFrailty in aging is driven by the dysregulation of multiple biological pathways. Protectin DX (PDX) is a docosahexaenoic acid (DHA)-derived molecule that alleviates many chronic inflammatory disorders, but its potential effects on frailty remain unknown.
Laís R. Perazza +4 more
openaire +2 more sources
Innate immunity is a key factor for the resolution of inflammation in asthma [PDF]
European Respiratory Review, 2015 The resolution of inflammation is an integral and natural part of the physiological response to tissue injury, infection and allergens or other noxious stimuli.
Cindy Barnig, Bruce D. Levy
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Hashimoto tiroiditi hastalarında IL-10, MCP-1, IFN gamma ve protectin D1 düzeylerinin değerlendirilmesi [PDF]
, 2022 Tıp Fakültesi, İç Hastalıkları A.B.D. Araştırma ProjesiAraştırma Projesi elektronik ortamda bulunmaktadır.Giriş: Hashimoto tiroiditi (HT), en yaygın otoimmün endokrin hastalıklardan biridir.
Özışık, Hatice
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