DHA- and EPA-derived resolvins, protectins, and maresins in airway inflammation [PDF]
Essential fatty acids can serve as important regulators of inflammation. A new window into mechanisms for the resolution of inflammation was opened with the identification and structural elucidation of mediators derived from these fatty acids with pro-resolving capacity.
Melody G, Duvall, Bruce D, Levy
openaire +2 more sources
Abstract Omega‐3 fatty acids (omega‐3s) are polyunsaturated fatty acids linked with numerous health benefits. Omega‐3s exhibit multifaceted activities through various mechanisms. Eicosapentaenoic acid (EPA) alleviates oxidative stress by lowering reactive oxygen species and improving oxidative stress in brain tissues and acts against neurodegenerative ...
Md Faruque Ahmad +12 more
wiley +1 more source
Tıp Fakültesi, İç Hastalıkları A.B.D. Araştırma ProjesiAraştırma Projesi elektronik ortamda bulunmaktadır.Giriş: Hashimoto tiroiditi (HT), en yaygın otoimmün endokrin hastalıklardan biridir.
Özışık, Hatice
core
In Vitro Biosynthetic Pathway Investigations of Neuroprotectin D1 (NPD1) and Protectin DX (PDX) by Human 12-Lipoxygenase, 15-Lipoxygenase-1, and 15-Lipoxygenase2 [PDF]
In this paper, human platelet 12-lipoxygenase [h12-LOX (ALOX12)], human reticulocyte 15-lipoxygenase-1 [h15-LOX-1 (ALOX15)], and human epithelial 15-lipoxygenase-2 [h15-LOX-2 (ALOX15B)] were observed to react with docosahexaenoic acid (DHA) and produce ...
Adriana Yamaguchi +11 more
core +1 more source
Mesenchymal stromal cells engage complement and complement receptor bearing innate effector cells to modulate immune responses. [PDF]
Infusion of human third-party mesenchymal stromal cells (MSCs) appears to be a promising therapy for acute graft-versus-host disease (aGvHD). To date, little is known about how MSCs interact with the body's innate immune system after clinical infusion ...
Guido Moll +12 more
doaj +1 more source
Fatty Acid Metabolism in Health and Cancer: From Fundamental Mechanisms to Therapeutic Application
The modulation of the TME by fatty acid metabolism primarily occurs through four key pathways: inflammation regulation, signal transduction, translation to TME, and oxidative stress. ABSTRACT Fatty acid metabolism (FAM) plays a vital role in maintaining health by supporting energy production, cellular structure, and signaling processes.
Na Hang +12 more
wiley +1 more source
Protectin D1n-3 DPA and resolvin D5n-3 DPA are effectors of intestinal protection
The resolution of inflammation is an active process orchestrated by specialized proresolving lipid mediators (SPM) that limit the host response within the affected tissue; failure of effective resolution may lead to tissue injury.
Deraison, Celine +11 more
core +1 more source
Differential Effects of Benralizumab and Mepolizumab on Pro‐Resolving Mediators
Allergy, EarlyView.
Jaime Bernaola +14 more
wiley +1 more source
Inflammatory insults, such as sepsis, pneumonia, aspiration, or trauma can trigger an inflammatory reaction leading to Acute Respiratory Distress Syndrome (ARDS). This study identified that different causes lead to differences in n−3 and n−6 polyunsaturated fatty acids (PUFAs) and their downstream oxylipins.
Laura A. Leuenberger +11 more
wiley +1 more source
Defective anterior wall of inguinal canal and its role in the pathophysiology of direct inguinal hernias [PDF]
Regrding pathophysiology of direct inguinal hernias the following are pointed our:1-Absence of contribution of fascia of transverses abdominis muscle along with fascia transversalis in making posterior wall of the inguinal canal causing defect point in ...
Abdolvahabi SA
doaj +2 more sources

