Results 21 to 30 of about 7,413 (211)

Selective Transport of Protein-Bound Uremic Toxins in Erythrocytes [PDF]

Toxins, 2019
To better understand the kinetics of protein-bound uremic toxins (PBUTs) during hemodialysis (HD), we investigated the distribution of hippuric acid (HA), indole-3-acetic acid (IAA), indoxyl sulfate (IS), and p-cresyl sulfate (pCS) in erythrocytes of HD patients.
Olivier Deltombe, Griet Glorieux, Sami Marzouki, Rosalinde Masereeuw, Daniel Schneditz, Sunny Eloot   +5 more
openaire   +5 more sources

Uremic Vascular Calcification: The Pathogenic Roles and Gastrointestinal Decontamination of Uremic Toxins

Toxins, 2020
Uremic vascular calcification (VC) commonly occurs during advanced chronic kidney disease (CKD) and significantly increases cardiovascular morbidity and mortality.
Chia-Ter Chao, Shih-Hua Lin
doaj   +1 more source

Protein-bound uremic toxins: putative modulators of calcineurin inhibitor exposure

Nephrology Dialysis Transplantation, 2022
No abstract ...
Laetitia Koppe, Christophe O Soulage
openaire   +4 more sources

Protein-Bound Uremic Toxins: New Insight from Clinical Studies [PDF]

Toxins, 2011
The uremic syndrome is attributed to the progressive retention of a large number of compounds which, under normal conditions, are excreted by healthy kidneys. The compounds are called uremic toxins when they interact negatively with biological functions.
Sophie Liabeuf, Tilman B. Drüeke, Ziad A. Massy   +2 more
openaire   +3 more sources

Single needle hemodialysis : is the past the future? [PDF]

, 2020
Whereas the usual way to gain access to the vascular bed for hemodialysis is by inserting two needles, an alternative option based on the introduction of only one needle has been available for several decades.
Vanholder, Raymond
core   +2 more sources

Carbamoylated nail proteins as assessed by near-infrared analysis are associated with load of uremic toxins and mortality in hemodialysis patients [PDF]

, 2020
Carbamoylation is an important risk factor for accelerated atherogenesis and mortality in patients undergoing hemodialysis (HD). We intended to explore whether carbamoylation as assessed by near-infrared (NIR) analysis of nail proteins is associated with
De Bruyne, Sander, De Buyzere, Marc, Delanghe, Joris, Delanghe, Sigurd, Glorieux, Griet, Himpe, Jonas, Speeckaert, Marijn, Van Biesen, Wim   +7 more
core   +1 more source

The relationship of indoxyl sulfate and p-cresyl sulfate with target cardiovascular proteins in hemodialysis patients

Scientific Reports, 2021
Protein-bound uremic toxins (Indoxyl sulfate [IS] and p-cresyl sulfate [PCS]) are both associated with cardiovascular (CV) and all-cause mortality in subjects with chronic kidney disease (CKD). Possible mechanisms have not been elucidated.
Ping-Hsun Wu, Yi-Ting Lin, Yi-Wen Chiu, Gabriel Baldanzi, Jiun-Chi Huang, Shih-Shin Liang, Su-Chu Lee, Szu-Chia Chen, Ya-Ling Hsu, Mei-Chuan Kuo, Shang-Jyh Hwang   +10 more
doaj   +1 more source

Pyroptosis: A Common Feature of Immune Cells of Haemodialysis Patients

Toxins, 2021
NLRP-3 inflammasome activation can result in interleukin-1β (IL-1β) release and inflammatory cell death (pyroptosis). Caspase-1 is able to trigger both processes.
Christof Ulrich, Leonie Kneser, Roman Fiedler, Julia Beckert, Susann Wildgrube, Eric Seibert, Sylvia Fick, Christoph Schäfer, Silke Markau, Bogusz Trojanowicz, Matthias Girndt   +10 more
doaj   +1 more source

AST-120 to target protein-bound uremic toxins improves cardiac output and kidney oxygenation in experimental chronic kidney disease.

Kidney & Blood Pressure Research, 2023
Introduction Chronic kidney disease (CKD) is a global health problem with increasing incidence which is closely associated with cardiac dysfunction. In CKD uremic toxins accumulate as kidney function declines.
Ebba Sivertsson, Sara Ceder, Masaomi Nangaku, Peter Hansell, Lina Nordquist, Fredrik Palm   +5 more
doaj   +1 more source

Enhanced Removal of Protein-Bound Uremic Toxins Using Displacers [PDF]

Clinical Journal of the American Society of Nephrology, 2019
Patients on maintenance dialysis suffer a substantial mortality risk. Traditionally, this increased mortality is attributed to enhanced cardiovascular damage, in itself mostly linked to hastened calcification and vascular stiffness related to inflammation.
Wim, Van Biesen, Sunny, Eloot
openaire   +2 more sources