Results 111 to 120 of about 5,276 (193)

PSAT1 Regulated Oxidation-Reduction Balance Affects the Growth and Prognosis of Epithelial Ovarian Cancer.

OncoTargets and therapy, 2020
A growing number of studies have found that the serine-glycine biosynthesis pathway is highly activated for biosynthesis in cancer progression and metastasis. Phosphoserine aminotransferase 1 (PSAT1) catalyzes the second step of the serine-glycine biosynthesis pathway; the effects and mechanism of PSAT1 in epithelial ovarian cancer (EOC) remains ...
Zhang,Yiqun, Li,Jiajia, Dong,Xuhui, Meng,Dan, Zhi,Xiuling, Yuan,Lei, Yao,Liangqing   +6 more
openaire   +3 more sources

Biomedical Knowledge Extraction Using Fuzzy Differential Profiles and Semantic Ranking [PDF]

, 2013
International audienceRecently, technologies such as DNA microarrays allow to generate big scale of transcriptomic data used to the aim of exploring background of genes.
Benabderrahmane, Sidahmed
core   +3 more sources

Additional file 1 of PSAT1 positively regulates the osteogenic lineage differentiation of periodontal ligament stem cells through the ATF4/PSAT1/Akt/GSK3β/β-catenin axis

Additional file 1: Table S1. The sequences of siRNAs.
Jia, Linglu, Li, Dongfang, Wang, Ya-Nan, Zhang, Dongjiao, Xu, Xin   +4 more
openaire   +1 more source

Additional file 4 of PSAT1 positively regulates the osteogenic lineage differentiation of periodontal ligament stem cells through the ATF4/PSAT1/Akt/GSK3β/β-catenin axis

Additional file 4: Figure S1. Validation of microarray results in PDLSCs by qRT-PCR.
Jia, Linglu, Li, Dongfang, Wang, Ya-Nan, Zhang, Dongjiao, Xu, Xin   +4 more
openaire   +1 more source

Phosphoserine aminotransferase deficiency diagnosed by whole‐exome sequencing and LC–MS/MS reanalysis: A case report and review of literature

Molecular Genetics & Genomic Medicine
Background Phosphoserine aminotransferase deficiency (PSATD) is an autosomal recessive disorder associated with hypertonia, psychomotor retardation, and acquired microcephaly.
Jiaci Li, Xinping Wei, Yuchen Sun, Xiaofang Chen, Ying Zhang, Xiaoyu Cui, Jianbo Shu, Dong Li, Chunquan Cai   +8 more
doaj   +1 more source

Overexpression of PSAT1 regulated by G9A sustains cell proliferation in colorectal cancer [PDF]

Signal Transduction and Targeted Therapy, 2020
Huijuan Wang, Longzhen Cui, Dandan Li, Ming Fan, Zhangnan Liu, Chunqi Liu, Sijing Pan, Lei Zhang, Hailong Zhang, Yinglan Zhao   +9 more
openaire   +2 more sources

Psat1-generated α-ketoglutarate and glutamine promote muscle stem cell activation and regeneration

Genes & Development
By satisfying bioenergetic demands, generating biomass, and providing metabolites serving as cofactors for chromatin modifiers, metabolism regulates adult stem cell biology. Here, we report that a branch of glycolysis, the serine biosynthesis pathway (SBP), is activated in regenerating muscle stem cells (MuSCs).
Ciuffoli, Veronica, Feng, Xuesong, Jiang, Kan, Acevedo-Luna, Natalia, Ko, Kyung Dae, Wang, A. Hong Jun, Riparini, Giulia, Khateb, Mamduh, Glancy, Brian, Dell'Orso, Stefania, Sartorelli, Vittorio   +10 more
openaire   +2 more sources

PSAT1 mediated EMT of colorectal cancer cells by regulating Pl3K/AKT signaling pathway

Journal of Cancer
Background: The metastasis of colorectal cancer (CRC) is one of the significant barriers impeding its treated consequence and bring about high mortality, less surgical resection rate and poor prognosis of CRC patients. PSAT1 is an enzyme involved in serine biosynthesis.
Wang, Mingjin, Zhang, Houshun, Lu, Zhiyuan, Su, Wenrui, Tan, Yanan, Wang, Jiayu, Jia, Xiaoyi   +6 more
openaire   +2 more sources

Issue Information

Animal Models and Experimental Medicine, Volume 9, Issue 1, Page 1-2, January 2026.
wiley   +1 more source

MicroRNA-365 suppresses cell growth and invasion in esophageal squamous cell carcinoma by modulating phosphoserine aminotransferase 1

Cancer Management and Research, 2018
Changjiang Sun,1 Xizhi Zhang,1 Yong Chen,1 Qingqing Jia,1 Jianqi Yang,1 Yusheng Shu2 1Department of Oncology, Subei People’s Hospital of Jiangsu Province, Yangzhou, Jiangsu, China; 2Department of Thoracic and Cardiovascular Surgery, Subei People ...
Sun C, Zhang X, Chen Y, Jia Q, Yang J, Shu Y   +5 more
doaj