Results 11 to 20 of about 3,665 (185)
PSAT1 regulates hair follicle growth and stem cell behavior in cashmere goats [PDF]
BMC Veterinary ResearchBackground The Arbas Cashmere Goat from Inner Mongolia is renowned for its superior-quality cashmere, which is primarily produced by secondary hair follicles (SHFs).
Xiao-yu Han +11 more
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Bioinformatics‐based discovery of the involvement of PSAT1 in mediating the anti‐lung adenocarcinoma activity of triptolide [PDF]
Animal Models and Experimental MedicineBackground Triptolide (TP) exhibits various pharmacological activities. Our previous studies have confirmed the efficacy of TP against lung adenocarcinoma (LUAD). However, the potent pharmacological activity of TP is underpinned by its complex mechanisms.
Zhiwen Cao +12 more
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Frontiers in Bioscience-Landmark, 2023 Purpose: Current evidence suggests that phosphoserine aminotransferase 1 (PSAT1) is overexpressed in various tumors. Herein, we investigate the significance of PSAT1 in non-small cell lung cancer (NSCLC) and its correlation with immune infiltration ...
Hongmu Li +8 more
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Differential expression of PSAT1 in pancreatic cancer.
, 2023 Cancer is a leading cause of death and pancreatic cancer is among the most lethal cancers (1, 2). We mined published microarray datasets (3, 4) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with pancreatic cancer, pancreatic adenocarcinoma (PDAC).
Shahan Mamoor
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Journal of Translational Medicine, 2023 Background Periodontal ligament stem cells (PDLSCs) are important seed cells for tissue engineering to realize the regeneration of alveolar bone. Understanding the gene regulatory mechanisms of osteogenic lineage differentiation in PDLSCs will facilitate
Linglu Jia +4 more
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Overexpression of the PSAT1 Gene in Nasopharyngeal Carcinoma Is an Indicator of Poor Prognosis [PDF]
Journal of Cancer, 2016 Nasopharyngeal carcinoma (NPC) is a common cancer in southern China and Southeast Asia, but risk stratification and treatment outcome in NPC patients remain suboptimal. Our study identified and validated metabolic drivers that are relevant to the pathogenesis of NPC using a published transcriptome.
Liao, Kuang-Ming +10 more
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Cellular Physiology and Biochemistry, 2016 Background/Aims: Phosphoserine aminotransferase 1 (PSAT1) is over-expressed in many carcinoma tissues, however little is known regarding its expression and function in esophageal carcinogenesis.
Bingyan Liu +9 more
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Probing the role of Coniferin and Tetrahydrocurcumin from Traditional Chinese medicine against PSAT1 in early-stage ovarian cancer: An in silico study. [PDF]
PLoS ONEOvarian cancer, a formidable gynaecological malignancy, poses a significant global health challenge, and it is characterised by late-stage diagnosis and a high mortality rate. Even in its early stages, when treatment choices are scarce, ovarian cancer is
Jia Zhang +5 more
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Regorafenib induces lethal autophagy arrest by stabilizing PSAT1 in glioblastoma [PDF]
Autophagy, 2019 GBM (glioblastoma multiforme) is the most common and aggressive brain tumor with no curative options available. Therefore, it is imperative to develop novel potent therapeutic drugs for GBM treatment. Here, we show that regorafenib, an oral multi-kinase inhibitor, exhibits superior therapeutic efficacy over temozolomide, the first-line chemotherapeutic
Jingwen Jiang +20 more
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Scientific Reports, 2023 Phosphoserine aminotransferase 1 (PSAT1) has been associated with the occurrence and development of various carcinomas; however, its function in uterine corpus endometrial carcinoma (UCEC) is unknown.
Min Wang, Song Yue, Zhu Yang
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