Results 41 to 50 of about 3,665 (185)
Juvenile-onset PSAT1-related neuropathy: A milder phenotype of serine deficiency disorder
Frontiers in Genetics, 2022 Background: Primary serine deficiency disorders have a broad range of the phenotypic spectrum. As an inborn error of metabolism, individuals with severe phenotype may be easily recognized with Neu-Laxova syndrome. However, late-onset mild phenotypes may be underdiagnosed and will lead to disastrous consequences due to treatment delays.Materials and ...
Yu Shen +12 more
openaire +3 more sources
陆军军医大学学报, 2023 Objective To screen and verify the Hub genes involved in conjugated bile acid-induced hepatocyte metabolism through transcriptome sequencing analysis. Methods Primary mouse hepatocytes were treated with taurocholic acid (TCA), and the gene expression of ...
ZHANG Mengni +4 more
doaj +1 more source
, 2021 An elevated expression of phosphoserine aminotransferase 1 (PSAT1) has been observed in multiple tumor types and is associated with poorer clinical outcomes.
James A. Bradley +7 more
core +1 more source
, 2020 Purpose: To identify the biological function of phosphoserine aminotransferase 1 (PSAT1) in regulating cell proliferation and apoptosis in multiple myeloma (MM).Methods: The mRNA and protein levels of PSAT1 were determined using quantitative real-time ...
Zhu, Hongqing +6 more
core +2 more sources
Expression of Serine Biosynthesis Pathway Genes in Breast Muscles of Iranian Native Turkeys with Divergent Feed Efficiency [PDF]
پژوهشهای علوم دامی ایران, 2022 Introduction: Feed is the main cost part of poultry production. High feed efficiency poultry produce less feed and less excrement per unit weight gain. Therefore, a comprehensive understanding of the biological mechanisms that control feed efficiency is ...
Zahra Pezeshkian +3 more
doaj +1 more source
Knock-down of PSAT1 Enhances Sensitivity of NSCLC Cells to Glutamine-limiting Conditions [PDF]
Anticancer Research, 2019 Phosphoserine aminotransferase 1 (PSAT1) is an enzyme implicated in serine biosynthesis, and its overexpression has been linked to cancer cell proliferation. Therefore, targeting PSAT1 is considered to be an anticancer strategy.The viability of non-small cell lung cancer (NSCLC) cells was measured by MTT assay.
Hyeon-Ok, Jin +10 more
openaire +2 more sources
Disease literature review of patients diagnosed with PSAT1-related serine biosynthesis defects.
, 2023 Disease literature review of patients diagnosed with PSAT1-related serine biosynthesis defects.
Martin S. Timour (17118016) +8 more
core +1 more source
PSAT1 promotes the progression of colorectal cancer by regulating Hippo-YAP/TAZ-ID1 axis via AMOT [PDF]
Molecular and Cellular BiochemistryXinyu Yuan, Xiansheng Lu, Le Xiong
exaly +2 more sources
Allele frequency and yeast growth scores for PSAT1 missense variants found in gnomAD.
, 2023 Allele frequency and yeast growth scores for PSAT1 missense variants found in gnomAD.
Martin S. Timour (17118016) +8 more
core +1 more source
BMC Medical Genomics, 2023 Background Ferroptosis plays an important role in the development of acute-on-chronic liver failure (ACLF). The present project aimed to identify and validate the potential ferroptosis-related genes in ACLF by bioinformatics analysis and experimental ...
Meixia Kuang +6 more
doaj +1 more source