Results 41 to 50 of about 3,887 (161)
Nanoscale Research Letters, 2020 It is unclear about the functional role of microRNA-133a-3p (miR-133a-3p) in intracranial aneurysm (IA). Hence, the aim of the present study was to investigate the regulatory role of miR-133a-3p on the regulation of vascular endothelial injury-induced IA
Qiang Jia +3 more
doaj +1 more source
, 2021 An elevated expression of phosphoserine aminotransferase 1 (PSAT1) has been observed in multiple tumor types and is associated with poorer clinical outcomes.
James A. Bradley +7 more
core +1 more source
, 2022 Supplementary Table from Metabolic and Nonmetabolic Functions of PSAT1 Coordinate Signaling Cascades to Confer EGFR Inhibitor Resistance and Drive Progression in Lung ...
Hui-Min Lei (14956797) +17 more
core +3 more sources
陆军军医大学学报, 2023 Objective To screen and verify the Hub genes involved in conjugated bile acid-induced hepatocyte metabolism through transcriptome sequencing analysis. Methods Primary mouse hepatocytes were treated with taurocholic acid (TCA), and the gene expression of ...
ZHANG Mengni +4 more
doaj +1 more source
A PSAT1 buff of YBX1 transcriptionally sustains HLA-E-mediated evasion of NK immunity. [PDF]
Proc Natl Acad Sci U S ADespite great success in certain cancers, immunotherapy made little progress in treating immune cold tumors, largely attributed to an immune-suppressive tumor microenvironment with elusive mechanisms. Here, we report in prostate cancer cells a positive feedback loop driven by phosphoserine aminotransferase 1 (PSAT1) that could be targeted to render ...
Zhang Y +17 more
europepmc +3 more sources
Expression of Serine Biosynthesis Pathway Genes in Breast Muscles of Iranian Native Turkeys with Divergent Feed Efficiency [PDF]
پژوهشهای علوم دامی ایران, 2022 Introduction: Feed is the main cost part of poultry production. High feed efficiency poultry produce less feed and less excrement per unit weight gain. Therefore, a comprehensive understanding of the biological mechanisms that control feed efficiency is ...
Zahra Pezeshkian +3 more
doaj +1 more source
A novel balanced chromosomal translocation found in subjects with schizophrenia and schizotypal personality disorder: altered l-serine level associated with disruption of PSAT1 gene expression [PDF]
, 2011 l-Serine is required for the synthesis of glycine and d-serine, both of which are NMDA receptor co-agonists. Although roles for d-serine and glycine have been suggested in schizophrenia, little is known about the role of the l-serine synthesizing cascade
Pickard, Benjamin S. +34 more
core +4 more sources
Allele frequency and yeast growth scores for PSAT1 missense variants found in gnomAD.
, 2023 Allele frequency and yeast growth scores for PSAT1 missense variants found in gnomAD.
Martin S. Timour (17118016) +8 more
core +1 more source
Disease literature review of patients diagnosed with PSAT1-related serine biosynthesis defects.
, 2023 Disease literature review of patients diagnosed with PSAT1-related serine biosynthesis defects.
Martin S. Timour (17118016) +8 more
core +1 more source
Juvenile-onset PSAT1-related neuropathy: A milder phenotype of serine deficiency disorder
Frontiers in Genetics, 2022 Background: Primary serine deficiency disorders have a broad range of the phenotypic spectrum. As an inborn error of metabolism, individuals with severe phenotype may be easily recognized with Neu-Laxova syndrome. However, late-onset mild phenotypes may be underdiagnosed and will lead to disastrous consequences due to treatment delays.Materials and ...
Yu Shen +12 more
openaire +3 more sources