Results 51 to 60 of about 3,887 (161)

CBS, PHGDH and PSAT1 interactive gene network.

, 2016
The differentially expressed genes CBS, PHGDH and PSAT1 interactive network generated automatically using the STRING database (STRING software 9.1) is shown here.
Indira Hewlett (329203), Santanu Biswas (2181154), Viswanath Ragupathy (656191), Sherwin Lee (656192), Krishnakumar Devadas (196381), Owen Wood (196407), Mohan Haleyurgirisetty (2181152)   +6 more
core   +1 more source

Overexpression of microRNA-195-5p reduces cisplatin resistance and angiogenesis in ovarian cancer by inhibiting the PSAT1-dependent GSK3β/β-catenin signaling pathway

Journal of Translational Medicine, 2019
Background Ovarian cancer (OC) is one of the leading causes for cancer-related deaths among women. MicroRNAs (miRs) have been proved to be vital to the development and progression of OC.
Jun Dai, Rujia Wei, Peihai Zhang, Beihua Kong   +3 more
doaj   +1 more source

Identification of potential ferroptosis hub genes in acute-on-chronic liver failure based on bioinformatics analysis and experimental verification

BMC Medical Genomics, 2023
Background Ferroptosis plays an important role in the development of acute-on-chronic liver failure (ACLF). The present project aimed to identify and validate the potential ferroptosis-related genes in ACLF by bioinformatics analysis and experimental ...
Meixia Kuang, Longhui Cai, Jing Zhao, Liqiao Huang, Yichun Ji, Bingyao Lv, Weihong Kuang   +6 more
doaj   +1 more source

ATF3 promotes the serine synthesis pathway and tumor growth under dietary serine restriction

Cell Reports, 2021
Summary: The serine synthesis pathway (SSP) involving metabolic enzymes phosphoglycerate dehydrogenase (PHGDH), phosphoserine aminotransferase 1 (PSAT1), and phosphoserine phosphatase (PSPH) drives intracellular serine biosynthesis and is indispensable ...
Xingyao Li, Daniel Gracilla, Lun Cai, Mingyi Zhang, Xiaolin Yu, Xiaoguang Chen, Junran Zhang, Xiaochun Long, Han-Fei Ding, Chunhong Yan   +9 more
doaj   +1 more source

Altered expression of genes involved in the serine synthesis pathway (SSP) in patients with acute myeloid leukemia [PDF]

Journal of Kerman University of Medical Sciences
Background: Acute myeloid leukemia (AML) is characterized by the uncontrolled proliferation of malignant cells, which rely on various metabolic pathways to sustain their survival and growth.
Parinaz Khadem, Ali Keshavarz, Mohammad Hossein Mohammadi, Fateme Mezginejad, Mehdi Allahbakhshian Farsani   +4 more
doaj   +1 more source

Knock-down of PSAT1 Enhances Sensitivity of NSCLC Cells to Glutamine-limiting Conditions [PDF]

Anticancer Research, 2019
Phosphoserine aminotransferase 1 (PSAT1) is an enzyme implicated in serine biosynthesis, and its overexpression has been linked to cancer cell proliferation. Therefore, targeting PSAT1 is considered to be an anticancer strategy.The viability of non-small cell lung cancer (NSCLC) cells was measured by MTT assay.
Hyeon-Ok, Jin, Sung-Eun, Hong, Ji-Young, Kim, Se-Kyeong, Jang, Young-Sun, Kim, Ju-Hee, Sim, Ac-Chin, Oh, Heyjin, Kim, Young Jun, Hong, Jin-Kyung, Lee, In-Chul, Park   +10 more
openaire   +2 more sources

Supplementary Data from Metabolic and Nonmetabolic Functions of PSAT1 Coordinate Signaling Cascades to Confer EGFR Inhibitor Resistance and Drive Progression in Lung Adenocarcinoma

, 2022
Supplementary Data from Metabolic and Nonmetabolic Functions of PSAT1 Coordinate Signaling Cascades to Confer EGFR Inhibitor Resistance and Drive Progression in Lung ...
Hui-Min Lei (14956797), Ling Xu (117663), Ming-Yu Luo (14956788), Wei-Ming Gu (12543710), Guanglei Zhuang (3506570), Lu Xu (386491), Pengfei Ma (80420), Ye Zhou (715680), Ya-Bin Tang (11118983), Jiang-Kai Dong (14956794), Ling Bi (14956803), Liang Zhu (14956806), Ying Shen (14956809), Ning-Xiang Shen (14956791), Cheng Wang (102692), Jing-Hua Zou (14956800), Hong-Zhuan Chen (6273275), Qian Liang (228504)   +17 more
core   +1 more source

Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cells-1

, 2011
Copyright information:Taken from "Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cells"http://www.molecular-cancer.com/content/7/1/14Molecular Cancer 2008;7():14-14.Published ...
Céline Gongora (86934), Emmanuel Conseiller (86931), Caroline Fraslon (86930), Vincent Denis (86928), Virginie Copois (86926), Nicole Bec (86678), Caroline Bascoul-Mollevi (86927), Franck Molina (86932), Bruno Robert (86929), Pierre Martineau (6238), Maguy Del Rio (86933), Christian Larroque (86679), Nadia Vié (86925)   +12 more
core   +1 more source

The innate immune kinase IKKε as a novel regulator of PSAT1 and serine metabolism [PDF]

, 2018
PhDInduced and activated as part of the innate immune response, the first line of defence against bacterial or viral infections, Inhibitor of Kappa-B Kinase ε (IKKε) triggers NF-κB and IFNβ signalling.
Jones, William Edward
core   +4 more sources

PSAT1 is upregulated by METTL3 to attenuate high glucose-induced retinal pigment epithelial cell apoptosis and oxidative stress

Diagnostic Pathology
Background Diabetic retinopathy (DR) is a major ocular complication of diabetes mellitus, and a significant cause of visual impairment and blindness in adults. Phosphoserine aminotransferase 1 (PSAT1) is an enzyme participating in serine synthesis, which
Xiaofeng Du, Yanting Wang, Fan Gao
doaj   +1 more source