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Molecular and cellular basis of pulmonary vascular remodeling in pulmonary hypertension

Progress in Cardiovascular Diseases, 2002
Clinical pulmonary hypertension is characterized by a sustained elevation in pulmonary arterial pressure. Pulmonary vascular remodeling involves structural changes in the normal architecture of the walls of pulmonary arteries. The process of vascular remodeling can occur as a primary response to injury, or stimulus such as hypoxia, within the ...
T K, Jeffery, N W, Morrell
openaire   +2 more sources

MMP8-mediated vascular remodeling in pulmonary hypertension

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Pulmonary arterial hypertension (PAH) is a vascular remodeling disease that impacts the cardiopulmonary system. Due to the currently limited understanding of vascular remodeling, a cure for PAH remains elusive. This study highlights the critical role of the STAT1 (signal transducer and activator of transcription 1)/MMP8 (matrix metallopeptidase 8)/DRP1
Xiaodong, Deng   +3 more
openaire   +2 more sources

Pulmonary Vascular Remodeling in Pulmonary Hypertension Mice Aggravated by Hypothyroidism

Endocrinology
Abstract Objective This study aimed to investigate the impact of hypothyroidism on pulmonary vascular remodeling (PVR) in pulmonary hypertension (PH) mice and the therapeutic effects of levothyroxine (L-T4). Methods Male C57BL/6J mice
Hongling Zhang   +3 more
openaire   +2 more sources

Epigenetics of Pulmonary Diseases

Medical Epigenetics, 2021
Narasaiah Kolliputi
exaly  

PULMONARY VASCULAR REMODELING

2006
I.F. McMurtry, S.A. Gebb, P.L. Jones
openaire   +1 more source

RGS5 as a Biomarker of Pericytes, Involvement in Vascular Remodeling and Pulmonary Arterial Hypertension

Vascular Health and Risk Management, 2023
Rui Du, Jianming Pei, Shumiao Zhang
exaly  

NMDA-Type Glutamate Receptor Activation Promotes Vascular Remodeling and Pulmonary Arterial Hypertension

Circulation, 2018
Frédéric Perros   +2 more
exaly  

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