Results 11 to 20 of about 7,462 (180)

Association of the ADORA2A receptor and CD73 polymorphisms with epilepsy

open access: yesFrontiers in Pharmacology, 2023
Single-nucleotide polymorphisms are connected with the risk of epilepsy on occurrence, progress, and the individual response to drugs. Progress in genomic technology is exposing the complex genetic architecture of epilepsy.
Nan-Rui Shi   +16 more
doaj   +1 more source

Imbalance in the Expression of Genes Associated with Purinergic Signalling in the Lung and Systemic Arteries of COPD Patients. [PDF]

open access: goldSci Rep, 2019
Careta O   +7 more
europepmc   +3 more sources

Increasing Efficiency of Repetitive Electroacupuncture on Purine- and Acid-Induced Pain During a Three-Week Treatment Schedule

open access: yesFrontiers in Pharmacology, 2021
Acupuncture (AP) is an important constituent of the therapeutic repertoire of traditional Chinese medicine and has been widely used to alleviate chronic painful conditions all over the world.
Jie Li   +8 more
doaj   +1 more source

Metabolic Changes Induced by Purinergic Signaling: Role in Food Intake

open access: yesFrontiers in Pharmacology, 2021
The purinergic signalling has a well-established role in the regulation of energy homeostasis, but there is growing evidence of its implication in the control of food intake.
Vanni Caruso   +8 more
doaj   +1 more source

Purinergic signalling in neuroregeneration

open access: yesNeural Regeneration Research, 2015
Geoffrey Burnstock
doaj   +2 more sources

Astrocytes in human central nervous system diseases: a frontier for new therapies

open access: yesSignal Transduction and Targeted Therapy, 2023
Astroglia are a broad class of neural parenchymal cells primarily dedicated to homoeostasis and defence of the central nervous system (CNS). Astroglia contribute to the pathophysiology of all neurological and neuropsychiatric disorders in ways that can ...
Alexei Verkhratsky   +7 more
doaj   +1 more source

Electroacupuncture prevents astrocyte atrophy to alleviate depression

open access: yesCell Death and Disease, 2023
Astrocyte atrophy is the main histopathological hallmark of major depressive disorder (MDD) in humans and in animal models of depression. Here we show that electroacupuncture prevents astrocyte atrophy in the prefrontal cortex and alleviates depressive ...
Si-Si Lin   +8 more
doaj   +1 more source

P2X7 Receptor–Mediated Inflammation in Cardiovascular Disease

open access: yesFrontiers in Pharmacology, 2021
Purinergic P2X7 receptor, a nonselective cation channel, is highly expressed in immune cells as well as cardiac smooth muscle cells and endothelial cells.
Junteng Zhou   +9 more
doaj   +1 more source

Red blood cell endothelial nitric oxide synthase: A major player in regulating cardiovascular health

open access: yesBritish Journal of Pharmacology, EarlyView., 2023
Abstract Red blood cells (RBCs) have traditionally been seen as simple carriers of gases and nutrients in the body. One important non‐canonical function of RBCs in the cardiovascular system is the regulation of nitric oxide (NO) metabolism. It has been shown that RBCs can scavenge NO, transport NO metabolites and produce NO in hypoxic conditions ...
Anthea LoBue   +7 more
wiley   +1 more source

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