Results 31 to 40 of about 4,761,571 (249)

Increasing Efficiency of Repetitive Electroacupuncture on Purine- and Acid-Induced Pain During a Three-Week Treatment Schedule

Frontiers in Pharmacology, 2021
Acupuncture (AP) is an important constituent of the therapeutic repertoire of traditional Chinese medicine and has been widely used to alleviate chronic painful conditions all over the world.
Jie Li, Ying Zhang, Peter Illes, Peter Illes, Peter Illes, Yong Tang, Yong Tang, Patrizia Rubini, Patrizia Rubini   +8 more
doaj   +1 more source

Metabolic Changes Induced by Purinergic Signaling: Role in Food Intake

Frontiers in Pharmacology, 2021
The purinergic signalling has a well-established role in the regulation of energy homeostasis, but there is growing evidence of its implication in the control of food intake.
Vanni Caruso, Vanni Caruso, Mariachiara Zuccarini, Mariachiara Zuccarini, Patrizia Di Iorio, Patrizia Di Iorio, Ishaq Muhammad, Maurizio Ronci, Maurizio Ronci   +8 more
doaj   +1 more source

Correcting an overactive exercise pressor reflex: A new role for purinergic signalling? [PDF]

Experimental Physiology
Fiona D. McBryde
doaj   +2 more sources

Purinergic signalling during development and ageing. [PDF]

Purinergic Signal, 2015
Burnstock G, Dale N.
europepmc   +2 more sources

Astrocytes in human central nervous system diseases: a frontier for new therapies

Signal Transduction and Targeted Therapy, 2023
Astroglia are a broad class of neural parenchymal cells primarily dedicated to homoeostasis and defence of the central nervous system (CNS). Astroglia contribute to the pathophysiology of all neurological and neuropsychiatric disorders in ways that can ...
Alexei Verkhratsky, Arthur Butt, Baoman Li, Peter Illes, Robert Zorec, Alexey Semyanov, Yong Tang, Michael V. Sofroniew   +7 more
doaj   +1 more source

Purinergic signalling, DAMPs and inflammation.

American Journal of Physiology - Cell Physiology, 2020
Danger sensing is one of the most fundamental evolutionary features enabling multicellular organisms to perceive potential threats, escape from risky situations, fight actual intruders and repair damage.
F. Di Virgilio, A. Sarti, R. Coutinho-Silva   +2 more
semanticscholar   +1 more source

Purinergic Signaling during Inflammation [PDF]

New England Journal of Medicine, 2012
Receptors for ATP and ADP and adenosine exert various effects. ATP and ADP signaling is mainly proinflammatory, and adenosine signaling is mainly antiinflammatory. Receptors for these nucleosides are emerging as therapeutic targets in a number of inflammatory and autoimmune diseases.
Holger K, Eltzschig, Michail V, Sitkovsky, Simon C, Robson   +2 more
openaire   +4 more sources

Electroacupuncture prevents astrocyte atrophy to alleviate depression

Cell Death and Disease, 2023
Astrocyte atrophy is the main histopathological hallmark of major depressive disorder (MDD) in humans and in animal models of depression. Here we show that electroacupuncture prevents astrocyte atrophy in the prefrontal cortex and alleviates depressive ...
Si-Si Lin, Bin Zhou, Bin-Jie Chen, Ruo-Tian Jiang, Baoman Li, Peter Illes, Alexey Semyanov, Yong Tang, Alexei Verkhratsky   +8 more
doaj   +1 more source

Purinergic signaling in epilepsy [PDF]

Journal of Neuroscience Research, 2016
Until recently, analysis of the mechanisms underlying epilepsy was centered on neuron dysfunctions. Accordingly, most of the available pharmacological treatments aim at reducing neuronal excitation or at potentiating neuronal inhibition. These therapeutic options can lead to obvious secondary effects, and, moreover, seizures cannot be controlled by any
Rassendren, François, Audinat, Etienne
openaire   +3 more sources

Purinergic signalling [PDF]

British Journal of Pharmacology, 2006
While there were early papers about the extracellular actions of purines, the role of ATP as a purinergic neurotransmitter in nonadrenergic, noncholinergic nerves in the gut and bladder in 1972 was a landmark discovery, although it met considerable resistance for the next 20 years. In the early 1990s, receptors for purines were cloned: four P1 receptor
openaire   +2 more sources