Results 31 to 40 of about 4,625,657 (223)

Correcting an overactive exercise pressor reflex: A new role for purinergic signalling? [PDF]

Experimental Physiology
Fiona D. McBryde
doaj   +2 more sources

Increasing Efficiency of Repetitive Electroacupuncture on Purine- and Acid-Induced Pain During a Three-Week Treatment Schedule

Frontiers in Pharmacology, 2021
Acupuncture (AP) is an important constituent of the therapeutic repertoire of traditional Chinese medicine and has been widely used to alleviate chronic painful conditions all over the world.
Jie Li, Ying Zhang, Peter Illes, Peter Illes, Peter Illes, Yong Tang, Yong Tang, Patrizia Rubini, Patrizia Rubini   +8 more
doaj   +1 more source

Metabolic Changes Induced by Purinergic Signaling: Role in Food Intake

Frontiers in Pharmacology, 2021
The purinergic signalling has a well-established role in the regulation of energy homeostasis, but there is growing evidence of its implication in the control of food intake.
Vanni Caruso, Vanni Caruso, Mariachiara Zuccarini, Mariachiara Zuccarini, Patrizia Di Iorio, Patrizia Di Iorio, Ishaq Muhammad, Maurizio Ronci, Maurizio Ronci   +8 more
doaj   +1 more source

Purinergic signalling during development and ageing. [PDF]

Purinergic Signal, 2015
Burnstock G, Dale N.
europepmc   +2 more sources

Astrocytes in human central nervous system diseases: a frontier for new therapies

Signal Transduction and Targeted Therapy, 2023
Astroglia are a broad class of neural parenchymal cells primarily dedicated to homoeostasis and defence of the central nervous system (CNS). Astroglia contribute to the pathophysiology of all neurological and neuropsychiatric disorders in ways that can ...
Alexei Verkhratsky, Arthur Butt, Baoman Li, Peter Illes, Robert Zorec, Alexey Semyanov, Yong Tang, Michael V. Sofroniew   +7 more
doaj   +1 more source

A companion to the preclinical common data elements and case report forms for neuropathology studies in epilepsy research. A report of the TASK3 WG2 Neuropathology Working Group of the ILAE/AES Joint Translational Task Force

Epilepsia Open, EarlyView., 2022
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force initiated the TASK3 working group to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Eleonora Aronica, Devin K. Binder, Meinrad Drexel, Chrysanthy Ikonomidou, Shilpa D. Kadam, Guenther Sperk, Christian Steinhäuser   +6 more
wiley   +1 more source

Electroacupuncture prevents astrocyte atrophy to alleviate depression

Cell Death and Disease, 2023
Astrocyte atrophy is the main histopathological hallmark of major depressive disorder (MDD) in humans and in animal models of depression. Here we show that electroacupuncture prevents astrocyte atrophy in the prefrontal cortex and alleviates depressive ...
Si-Si Lin, Bin Zhou, Bin-Jie Chen, Ruo-Tian Jiang, Baoman Li, Peter Illes, Alexey Semyanov, Yong Tang, Alexei Verkhratsky   +8 more
doaj   +1 more source

Purinergic signalling, DAMPs and inflammation.

American Journal of Physiology - Cell Physiology, 2020
Danger sensing is one of the most fundamental evolutionary features enabling multicellular organisms to perceive potential threats, escape from risky situations, fight actual intruders and repair damage.
F. Di Virgilio, A. Sarti, R. Coutinho-Silva   +2 more
semanticscholar   +1 more source

P2X7 Receptor–Mediated Inflammation in Cardiovascular Disease

Frontiers in Pharmacology, 2021
Purinergic P2X7 receptor, a nonselective cation channel, is highly expressed in immune cells as well as cardiac smooth muscle cells and endothelial cells.
Junteng Zhou, Zhichao Zhou, Xiaojing Liu, Xiaojing Liu, Hai-Yan Yin, Hai-Yan Yin, Yong Tang, Yong Tang, Xin Cao, Xin Cao   +9 more
doaj   +1 more source

Purinergic signalling pathway: therapeutic target in ovarian cancer

Egyptian Journal of Medical Human Genetics, 2020
Background The lack of early diagnostic tools and the development of chemoresistance have made ovarian cancer (OC) one of the deadliest gynaecological cancers.
Nisha Chandran, Mahalaxmi Iyer, Zothan Siama, Balachandar Vellingiri, Arul Narayanasamy   +4 more
doaj   +1 more source