Results 61 to 70 of about 9,290 (210)

Ordered and ushered; the assembly and translocation of the adhesive Type I and P Pili [PDF]

open access: yes, 2013
Type I and P pili are chaperone-usher pili of uropathogenic Escherichia coli, which allow bacteria to adhere to host cell receptors. Pilus formation and secretion are orchestrated by two accessory proteins, a chaperone, which catalyses pilus subunit ...
Aberg   +19 more
core   +2 more sources

Dinuclear Rhodium(I)–N‐Heterocyclic Carbene Complexes as Alkyne Hydropyridonation Catalysts

open access: yesEuropean Journal of Inorganic Chemistry, Volume 29, Issue 7, 2 March 2026.
Catalyst Improvement by NHC tuning: A series of new RhI–NHC dinuclear complexes has been revealed as efficient alkyne hydropyridonation catalysts. 333053IMes complex displays the highest reactivity of the series, suggesting that a moderate steric demand combined with balanced σ‐donation facilitates precatalyst activation and substrate exchange.
Belinda Español‐Sánchez   +7 more
wiley   +1 more source

Synthesis and chemical properties of 3-acyl- and 3-carbethoxy-4-pyrones [PDF]

open access: yes, 2013
Реакция 1-арил-2-диметиламинометиленбутан-1,3-дионов с диэтиоксалатом в присутствии гидрида натрия в ТГФ приводит к образованию этил 5-ароил-4-оксо-4Н-пиран-2- карбоксилатам, из которых 4-оксо-6-арил-4Н-пиран-2-карбоновые кислота (6- арилкомановая ...
Obydennov, D. L.   +1 more
core  

SAM-dependent enzyme-catalysed pericyclic reactions in natural product biosynthesis. [PDF]

open access: yes, 2017
Pericyclic reactions-which proceed in a concerted fashion through a cyclic transition state-are among the most powerful synthetic transformations used to make multiple regioselective and stereoselective carbon-carbon bonds.
Chen, Mengbin   +9 more
core   +1 more source

Targeting cancer cell mitochondria with a multivalent source of singlet oxygen

open access: yesSmart Molecules, Volume 4, Issue 1, March 2026.
Multivalent source of singlet oxygen can effectively target cancer cell mitochondria and cause improved cancer cell selective cytotoxicity at low micromolar concentrations. Abstract Naphthalene, anthracene and pyridone endoperoxides are known to thermally release singlet oxygen.
Wanwan Wang   +4 more
wiley   +1 more source

Controle de plantas daninhas na cultura do milho utilizando leucena (Leucaena leucocephala (Lam.) de wit). [PDF]

open access: yes, 2018
Avaliou-se o efeito da parte aérea da leucena, em condiçoes de casa de vegetação e campo, sobre o desenvolvimento de plantas daninhas, fitotoxicidade para o milho e acréscimo de nitrogênio para a cultura. Em casa de vegetação (vasos) foram avaliadas 25 t
PEREIRA FILHO, I. A.   +2 more
core   +1 more source

Nicotinamide (Vitamin B3) Deficiency in Follicular Fluid of Patients With Ovarian Ageing

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 6, March 2026.
ABSTRACT Nicotinamide is an essential precursor of NAD involved in energy metabolism. A decline in NAD levels across tissues during ageing is well‐documented, and NAD metabolism has been implicated in ovarian ageing. We investigated the relationship between ovarian ageing and the levels of nicotinamide (NAM) and its metabolite 1‐methylnicotinamide (MNA)
Cinzia Bocca   +5 more
wiley   +1 more source

A Short Synthesis of (±)-3-Demethoxyerythratidinone by Ligand Controlled Selective Heck Cyclization of Equilibrating Enamines [PDF]

open access: yes, 2017
A short, 5-step total synthesis of (±)-3-demethoxyerythratidinone from a simple pyrrole derivative is described. Features include the formation of gram quantities of a key tricylic aziridine from a challenging photochemical cascade reaction through the ...
Albini   +39 more
core   +2 more sources

Timing of NAD Deficiency During Organogenesis Dictates Defect Type and Penetrance

open access: yesThe FASEB Journal, Volume 40, Issue 3, 15 February 2026.
Pregnant mice on a vitamin B3‐free and tryptophan‐limited diet have embryos with Congenital NAD Deficiency Disorder, characterized by malformations and/or death. We longitudinally tracked the maternal NAD metabolome, embryo growth, and malformation occurrence. Mice with lower NAD Salvage Pathway metabolite levels and minimal levels of derived excretion
Kayleigh Bozon   +6 more
wiley   +1 more source

Structural and molecular biology of a protein-polymerizing nanomachine for pilus biogenesis [PDF]

open access: yes, 2017
Bacteria produce protein polymers on their surface called pili or fimbriae that serve either as attachment devices or as conduits for secreted substrates.
Waksman, Gabriel
core   +1 more source

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