Results 71 to 80 of about 16,008 (266)

Design, Synthesis and Antifibrotic Activities of Carbohydrate- Modified 1-(Substituted aryl)-5-trifluoromethyl-2(1H) Pyridones

Molecules, 2012
Pirfenidone, a pyridone compound, is an effective and novel antifibrotic agent. In this article, we describe the design, synthesis and activity evaluation of novel antifibrotic agents, 1-(substituted aryl)-5-trifluoromethyl-2(1H) pyridones modified with ...
Lijian Tao, Zhongjun Li, Renna Luo, Gaoyun Hu, Qi Hou, Zhiqi Lao, Lingling Xuan, Jinye Bai, Xiangbao Meng, Qinghua Lou   +9 more
doaj   +1 more source

Convenient Replacement of the Hydroxy by an Amino Group in 4 Hydroxycoumarin and 4-Hydroxy-6-methyl-2-pyrone under Microwave Irradiation

Molecules, 2004
The reaction of 4-hydroxycoumarin (1) with some primary amines 2a-h and morpholine (2i) under microwave irradiation occurred without opening of the lactone ring to give N-substituted 4-aminocoumarins 3a-i in excellent yields.
Ivo C. Ivanov, Edmont V. Stoyanov
doaj   +1 more source

Cobalt(iii)-catalyzed site-selective C–H amidation of pyridones and isoquinolones

RSC Advances, 2018
In this study, Cp*Co(iii)-catalyzed site-selective amidation of pyridones and isoquinolones using oxazolones as the amidation reagent is reported. This approach features mild conditions, high efficiency and good functional tolerance.
Feng Gao, Xu Han, Chunpu Li, Lingjun Liu, Zhanqing Cong, Hong Liu   +5 more
semanticscholar   +1 more source

Synthesis, characterization, and antimicrobial evaluation of novel 5-benzoyl-N-substituted amino- and 5-benzoyl-N-sulfonylamino-4-alkylsulfanyl-2-pyridones

Drug Design, Development and Therapy, 2017
Galal Elgemeie,1 Farag Altalbawy,2,3 Mohammed Alfaidi,3 Rania Azab,2,4 Atef Hassan5 1Department of Chemistry, Faculty of Science, Helwan University, Helwan, 2National Institute of Laser Enhanced Sciences (NILES), Cairo University, Giza, Egypt ...
Elgemeie G, Altalbawy F, Alfaidi M, Azab R, Hassan A   +4 more
doaj  

Dakin-West Trick in the Design of Novel 2-Alkyl(aralkyl) Derivatives of Oxazolo[3,2-a]pyridines

Molecules, 2005
A series of previously unavailable derivatives of 2-alkyl- and 2-benzylderivatives of oxazolo[3,2-a]pyridines III were obtained via tandem ring opening and ring closure from stable mesoionic 3-acyloxazolo[3,2-a]pyridinium-2-olates I.
Eugene V. Babaev, Alexander A. Bush, Zeinul-Gabiden M. Kazhkenov   +2 more
doaj   +1 more source

Synthesis of 5-(substituted phenylazo)-6-hydroxy-4-methyl-3-cyano-2-pyridones from ethyl 3-oxo-2-(substituted phenylazo)butanoates, Short communication [PDF]

Journal of the Serbian Chemical Society, 2011
A new procedure for the synthesis of known azo pyridone dyes is presented. A series of 5-(substituted arylazo)-6-hydroxy-4-methyl-3-cyano-2-pyridones were prepared from ethyl 3-oxo-2-(substituted phenylazo)butanoates and cyanoacetamide in acetone using ...
GORDANA UŠĆUMLIĆ, DUŠAN MIJIN, NATAŠA VALENTIĆ, JASMINA DOSTANIĆ   +3 more
doaj  

Synthesis and Cyclizations of N-(2,3-, 3,4- and 3,5-Dimethylphenyl)-β-alanines

Molecules, 2005
A series of 1-aryl substituted dihydro-, 5-methyldihydro- and 6-methyl-dihydro-2,4(1H,3H)pyrimidinediones and their 2-thio analogues were obtained byreaction of the corresponding β-alanines or α-methyl- and β-methyl-β-alanines with ureaor ...
Gema Mikulskiene, Vytautas Mickevicius, Rita Vaickelioniene   +2 more
doaj   +1 more source

Rhodium(III)-Catalyzed C-H Activation/Heterocyclization as a Macrocyclization Strategy. Synthesis of Macrocyclic Pyridones.

Organic Letters, 2017
Structurally diverse macrocyclic pyridones can be efficiently synthesized by a rhodium(III)-catalyzed C-H activation/heterocyclization of ω-alkynyl α-substituted acrylic hydroxamates.
J. Krieger, D. Lesuisse, Gino Ricci, M. Perrin, C. Meyer, J. Cossy   +5 more
semanticscholar   +1 more source

THE PROPERTIES OF n‐PROPYL 3:5‐DI‐IODO‐4‐PYRIDONE‐N‐ACETATE (PROPYLIODONE) [PDF]

, 1953
E. G. TOMICH, B. BASIL, Benjamin Davis
openalex   +1 more source

EXPERIMENTS ON THE SYNTHESIS OF CYTISINE. PART I. SYNTHESIS OF ETHYL 3 : 5-DICARBETHOXYPYRONE-6-ACETATE AND THE CORRESPONDING PYRIDONES. [PDF]

, 1938
S. K. MITRA
openalex   +1 more source