Results 141 to 150 of about 53,711 (308)

Manipulation of cancer cell pyroptosis for therapeutic approaches: challenges and opportunities

open access: yesBiomarker Research
Remarkable advances have been achieved following discoveries that gasdermins are the executioners of pyroptosis. The pyroptotic process consists a subcellular permeabilization phase and a cell lysis phase, the latter of which is irreversible.
Rui Miao   +7 more
doaj   +1 more source

A Comprehensive Review of Food-Derived Compounds Targeting Pyroptosis for Colitis Therapy: From Effects to Mechanisms

open access: yes
Jin-Wei Zhao,1 Lu-Yao Li,1 Fang-Wang Ye,1 Wei-Yi Zhao2 1Department of Hepatopancreatobiliary Surgery, The Second Hospital of Jilin University, Changchun, Jilin, 130022, People’s Republic of China; 2Medical College of Yanbian University, Yanbian, Jilin ...
Ye FW, Zhao JW, Zhao WY, Li LY
core  

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

open access: yesBMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan   +8 more
wiley   +1 more source

Pyroptosis the Emerging Link Between Gut Microbiota and Multiple Sclerosis

open access: yes
Hua Fan,* Ruile Shen,* Junqiang Yan,* Yongjie Bai, Qizhi Fu, Xiaofei Shi, Ganqin Du, Dongmei Wang The First Affiliated Hospital, College of Clinical Medicine, Henan University of Science and Technology, Luoyang, 471003, People’s Republic of ...
Fu Q   +7 more
core  

A Review of Pyroptosis in Liver Disease [PDF]

open access: yes
Pyroptosis is a new form of programmed cell death that is different from cell necrosis, apoptosis, and autophagy. It is characterized by the rupture of cell membranes mediated by Gasdermin and the release of cell contents and pro-inflammatory factors ...
Hao Li, Li Hao
core   +1 more source

The role of pyroptosis in ovarian cancer

open access: yesDiscover Oncology
Pyroptosis is a novel form of programmed cell death that depends on gasdermin-mediated pore formation in the plasma membrane and the release of inflammatory factors. Pyroptosis is closely linked to the occurrence and progression of almost all types of cancer, including ovarian cancer, which is the seventh most common malignancy among women worldwide ...
Zhou, Yingzhi   +3 more
openaire   +2 more sources

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

open access: yesBMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang   +12 more
wiley   +1 more source

Electroacupuncture Inhibits NLRP3-Mediated Microglial Pyroptosis to Ameliorate Chronic Neuropathic Pain in Rats

open access: yes
Wenyun Kui, Yanan Li, Zhen Gu, Lei Xie, Aiping Huang, Shuyi Kong, Lilong Song, Lingxing Li, Jun Yu, Chun-Chun Xue, Kaiqiang Wang Department of Pain, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese ...
Song L   +10 more
core  

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

open access: yesBMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao   +4 more
wiley   +1 more source

From Inflammasomes to Pyroptosis: Molecular Mechanisms in Chronic Intestinal Diseases — Opportunity or Challenge?

open access: yes
Jintao Fang,1,* Weihan Zhu,1,* Dian Yu,1 Lujian Zhu,2 Haorui Zha,1 Jingyi Tang,3 Yujia Li,1 Xiaxin Zhu,1 Ting Zhao,1 Wei Zhang1,4 1The Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, 310000, People’s Republic of ...
Zhang W   +9 more
core  

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