Results 51 to 60 of about 2,043 (197)

Radiation carcinogenesis: radioprotectors and photosensitizers [PDF]

, 1982
This paper outlines 1) some of the salient features of radiation carcinogenesis that are pertinent to the questions of how the carcinogenic effects might be influenced, 2) the effects of radioprotectors on ionizing radiation-induced cancer, and 3) the ...
Fry, R.J.M.
core  

Selenium: Chemical biology, toxicology and radioprotection

Biomedical Research Journal, 2016
Selenium, a micronutrient and an active constituent of important redox enzymes like glutathione peroxidase (GPx) and thioredoxin reductase (TrxR), has been investigated extensively by researchers all over the world for the last four to five decades. Both
Kavirayani Indira Priyadarsini, Beena Govind Singh, Amit Kunwar   +2 more
doaj   +1 more source

RADIOPROTECTORS AND THEIR CHARACTERISTICS. APPLICATIONS OF RADIOPROTECTORS

This article is devoted to the study of radioprotectors, their characteristics, mechanisms of action, and practical applications in modern medicine and radiation protection. The increasing use of ionizing radiation in healthcare, industry, scientific research, and nuclear technologies has highlighted the importance of effective methods for protecting ...
Xodjamova, Gulbahor, Abduraximov, Muhammadqodir   +1 more
openaire   +1 more source

Metallofullerenol Sc3N@C80(OH)18: A New Generation Radioprotector Protecting Human Erythrocytes Against Multiple Biochemical Damage Modes Upon Gamma Irradiation, Identifying It as a Scavenger of Short‐ and Long‐Lived Radicals

Advanced Healthcare Materials, Volume 15, Issue 7, 16 February 2026.
Metallofullerenol Sc3N@C80(OH)18 demonstrates strong radioprotective properties as a scavenger of both short‐ and long‐lived radicals. The study reveals protection of human erythrocytes from γ‐radiation–induced biochemical damage via post‐irradiation removal of primary and secondary reactive oxidants, supported by pulse radiolysis kinetics.
Jacek Grebowski, Maciej Studzian, Szymon Lekki‐Porebski, Anna Konarska, Marian Wolszczak, Grzegorz Litwinienko, Lukasz Pulaski   +6 more
wiley   +1 more source

Inhibition of ferroptosis by microbiota‐derived lithocholic acid underlies the intestinal radioprotection of a host defensin‐derived oligopeptide

iMeta, Volume 5, Issue 1, February 2026.
AT9(C/G), an oligopeptide derived from human defensin 5, enriches Bifidobacterium pseudolongum and increases lithocholic acid (LCA) levels in the intestine. Reduced levels of LCA link to increased severity of ionizing radiation‐induced intestinal injury (IRIII) in both murine and clinical studies.
Xue Ouyang, Yingjuan He, Zihao Jin, Shaobo Wang, Gaomei Zhao, Xiaona Su, Jia Du, Yin Chen, Chengzhang Tan, Xin Li, Songling Han, Bin Wang, Jinghong Zhao, Jianqin Niu, Chuan Chen, Junping Wang, Cheng Wang   +16 more
wiley   +1 more source

Combining Pharmacological Countermeasures to Attenuate the Acute Radiation Syndrome—A Concise Review

Molecules, 2017
The goal of combined pharmacological approaches in the treatment of the acute radiation syndrome (ARS) is to obtain an effective therapy producing a minimum of undesirable side effects.
Michal Hofer, Zuzana Hoferová, Daniel Depeš, Martin Falk   +3 more
doaj   +1 more source

TMEM131‐Mediated Soluble TRAIL Triggered Type II Alveolar Epithelial Cell Senescence in Radiation‐Induced Lung Injury

Advanced Science, Volume 13, Issue 6, 30 January 2026.
TMEM131 recruits the COPII complex to accelerate TRAIL transportation from endoplasmic reticulum to Golgi apparatus, and promotes soluble TRAIL secretion. TRAIL inhibits mitophagy and induces senescence through DR5 receptor in type II alveolar epithelial cells, ultimately driving radiation‐induced lung injury (RILI) progression.
Linzhi Han, Chunsheng Wang, Xiuli Guo, Yuan Luo, Jianguo Zhang, Fajian He, Zihang Zeng, Jiang Luo, Wen Ouyang, Yan Gong, Conghua Xie   +10 more
wiley   +1 more source

Evaluation of the radioprotective potential of fumaric acid, 3-hydroxypyridine fumarate and deanol aceglumate under the action of γ-radiation, protons and ¹²C ions on human cells

Радиационная гигиена
The relevance of the research of new radioprotectors is due to the need to protect healthy tissues during radiation therapy. Existing drugs have serious side effects, which requires the search for safer and more effective analogues.The aim of the work is
P. S. Kuptsova, L. N. Komarova, E. R. Olkhovaya, A. K. Lapenko, S. V. Shkavrov, I. S. Kuptsov, V. O. Saburov   +6 more
doaj   +1 more source

Evaluation of Silymarin as a Promising Radioprotector

Zeitschrift für Naturforschung C, 2010
Silymarin, a purified extract of seeds of Silybum marianum L. and well known for its hepatoprotective abilities, has been evaluated for inherent utility as a radioprotective agent. A fraction (INM-7035) was authenticated by characterizing the percentage composition of silybin A and B (39.9% and 57.4%).
Manish, Adhikari, Rajesh, Arora, Raman, Chawla, Jyoti, Sharma, Atlar Singh, Dhaker, Damodar, Gupta, Neha, Dubey, Raj, Kumar, Veselin, Ivanov, Veselina, Gadjeva, Renata, Gevrenova, Rakesh Kumar, Sharma   +11 more
openaire   +2 more sources

Mechanistic Investigation of Salidroside Modulates Iron Overload to Mitigate Radiation‐Induced Heart Disease

Cardiovascular Therapeutics, Volume 2026, Issue 1, 2026.
Objective Radiation‐induced heart disease (RIHD) severely compromises the long‐term survival of cancer patients. Although ferroptosis has been implicated as a key contributor to RIHD pathogenesis, the underlying regulatory mechanisms remain incompletely defined.
Jiaming Lai, Rong Wang, Shenglin Zhang, Li Li, Likun Qi, Zhenyao Dong, Ranran Yan, Bo Zhang, Guoquan Li, Hao Cai, Satabdi Datta Choudhury   +10 more
wiley   +1 more source