Results 71 to 80 of about 2,043 (197)

Targeting gut microbiota and metabolites in cancer radiotherapy

open access: yesClinical and Translational Medicine, Volume 15, Issue 10, October 2025.
Radiotherapy (RT) efficacy and toxicity are influenced by gut microbiota and their metabolites. This review explores how probiotics, prebiotics, and microbial byproducts (e.g., short‐chain fatty acids [SCFAs]) mitigate radiation damage and enhance tumour radiosensitivity.
Shuling Ma   +6 more
wiley   +1 more source

High-Throughput Screening of Radioprotectors Using Rat Thymocytes

open access: yes, 2016
We invented a high-throughput screening method for the examination of radioprotective activity of chemical compounds using rat thymocytes. X-irradiation of the rat thymocytes induced apoptosis, leading to a significant cell shrinkage, which could be ...
Megumi Ueno (1922005)   +5 more
core   +1 more source

Prospects in the development of natural radioprotective therapeutics with anti-cancer properties from the plants of Uttarakhand region of India

open access: yesJournal of Ayurveda and Integrative Medicine, 2016
Radioprotective agents are substances those reduce the effects of radiation in healthy tissues while maintaining the sensitivity to radiation damage in tumor cells.
Sakshi Painuli, Navin Kumar
doaj   +1 more source

Radiation affection and radioprotectors

open access: yes, 2005
У ретроспективному огляді показано, що класичні вимоги до радіопротекторів, які базуються на їх ефективності за умов опромінення летальними дозами, непридатні для пом'якшення негативного впливу низьких доз радіації. Постчорнобильська ситуація підтвердила
Мойсеєв, М.   +3 more
core   +1 more source

Nitrous oxide—radiosensitizer or radioprotector?

open access: yesThe British Journal of Radiology, 1991
As part of a wider study of the radiobiological effects of narcotic gas mixtures (Conere, 1989) the possible radiation protection of Chinese hamster ovary cells (CHO) using a 99% nitrous oxide: 1 ± 0.05% oxygen gas mixture has been investigated. This gas mixture was used in the expectation that the narcotic component in the mixture might displace ...
T J, Conere, A, Brock, A H, Nias
openaire   +2 more sources

Enhancing Radiotherapy Tolerance With Papaya Seed‐Derived Nanoemulsions

open access: yesFood Science &Nutrition, Volume 13, Issue 4, April 2025.
Flavonoid‐rich Carica papaya (CP) seeds were used to develop Sunflower Oil‐based Papaya Oil (SPO) and Pure Papaya Oil (PPO), alongside their nanoemulsions (SPOE and PPOE), for potential radioprotective applications. Post‐radiation testing on HaCaT cell lines demonstrated significant enhancement in cell viability, with PPOE and SPOE achieving 75.85% and
Muhammad Tariq Siddiqui   +4 more
wiley   +1 more source

Chemical Radioprotectors

open access: yes, 2018
Ionizirajuće zračenje kada dođe u interakciju s ljudskim tijelom može imati iznimno štetne utjecaje. Kemijski radioprotektori koriste se kao protumjera radijaciji, smanjujući štetne učinke ionizirajućeg zračenja.
Bogeljić, Vedran
core   +1 more source

Substituted Piperazines as Novel Potential Radioprotective Agents

open access: yesMolecules, 2020
The increasing risk of radiation exposure underlines the need for novel radioprotective agents. Hence, a series of novel 1-(2-hydroxyethyl)piperazine derivatives were designed and synthesized. Some of the compounds protected human cells against radiation-
Alzbeta Filipova   +15 more
doaj   +1 more source

Radioprotective Effects of Vitamin C, Cimetidine, and Famotidine on Lipid Peroxidase and Hepatic Glutathione Levels in Mouse Liver

open access: yesInternational Journal of Cell Biology, Volume 2025, Issue 1, 2025.
Radiation therapy is one of the most effective treatments for approximately 60% of patients with cancer. During radiation exposure, the overproduction of reactive oxygen species (ROS) disrupts the lipid layer of the membrane, leading to subsequent peroxide radical formation.
Mana Gholami   +6 more
wiley   +1 more source

Nomenclature of radioprotective medical agents for major radiation accidents

open access: yesРадиационная гигиена
The widespread use of nuclear and radiation technologies necessitates preparedness for response to radiological emergencies. The application of medical countermeasures aimed at mitigating the adverse effects of ionizing radiation is a key element of risk
G. A. Gorsky   +3 more
doaj   +1 more source

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