Results 61 to 70 of about 2,043 (197)

Evaluation of the radioprotective efficacy of water soluble sodium salt of n-acetylcysteine in experimental studies

Радиационная гигиена
Although several radioprotectors have been developed, their clinical use remains limited due to toxicity, a narrow therapeutic window, and reduced efficacy when administered post irradiation.
A. A. Popova, L. A. Chipiga, D. N. Maystrenko, V. I. Evtushenko, A. A. Stanzhevskiy, D. N. Nikolaev, T. E. Ponezha, Yu. N. Vinogradova, E. B. Ioffe, A. D. Maistrenko   +9 more
doaj   +1 more source

ENDOTHELIAL DYSFUNCTION UNDER INFLUENCE OF IONIZING RADIATION: PATHOGENETIC BASIS AND OPPORTUNITIES OF PHARMACOLOGICAL CORRECTION

Кубанский научный медицинский вестник, 2018
The problem of radiation-induced lesions is becoming increasingly urgent. Studies in recent years show that one of the most vulnerable  tissues is the endothelium when exposed to high doses of ionizing  radiation.
K. V. SAROYAN, I. N. SYTNIK, V. O. SOLDATOV, M. A. PERSHINA, N. I. ZHERNAKOVA, S. V. POVETKIN, L. N. SERNOV   +6 more
doaj   +1 more source

Skin‐Protective Effects of DeinoPol‐BRD125, a Microbial Exopolysaccharide From Deinococcus radiodurans, on Epidermal Hydration and Barrier Recovery

Dermatologic Therapy, Volume 2026, Issue 1, 2026.
Deinococcus radiodurans is an extremophile bacterium renowned for its extraordinary resistance to environmental stress, partly mediated by its exopolysaccharide (EPS), DeinoPol. DeinoPol‐BRD125, derived from a high‐producing strain, exhibits potent antioxidative and cytoprotective properties, but its dermatological relevance remains largely unexplored.
Ki Bum Ahn, Hyun Jung Ji, Sun-Young Kim, Yeongkag Kwon, Min-Kyu Kim, Ho Seong Seo, Hae Ran Park, Suraiya Saleem   +7 more
wiley   +1 more source

Common onion extract (Allium cepa): radioprotective or radiosensitizing?

Brazilian Journal of Radiation Sciences
Currently, ionizing radiation has been used on a large scale in different areas of knowledge. However, despite the existence of several radioprotection regulations for workers, patients and members of the public, these are not sufficient to completely ...
Raquel Cordeiro de Oliveira, Evelin Mirelle Lima Araújo, Osana Diniz Ferreira, Suy Ferreira Hwang, Ana Maria Mendonça Albuquerque de Melo, Mariana Esposito Mendes, Thiago Henrique Napoleão, Fabiana Farias de Lima   +7 more
doaj   +1 more source

Physico-chemical evaluation of rationally designed melanins as novel nature-inspired radioprotectors. [PDF]

PLoS ONE, 2009
Melanin, a high-molecular weight pigment that is ubiquitous in nature, protects melanized microorganisms against high doses of ionizing radiation. However, the physics of melanin interaction with ionizing radiation is unknown.We rationally designed ...
Andrew D Schweitzer, Robertha C Howell, Zewei Jiang, Ruth A Bryan, Gary Gerfen, Chin-Cheng Chen, Dennis Mah, Sean Cahill, Arturo Casadevall, Ekaterina Dadachova   +9 more
doaj   +1 more source

Radioprotectors, Radiomitigators, and Radiosensitizers

, 2023
Abstract This chapter gives an overview of molecules and mechanisms able to intervene with the biological effects of ionizing radiation (IR), either related to their clinical use in radiotherapy or in the field of radiation protection in case of an accidental exposure to radiation and/or nuclear emergencies.
Montoro A., Obrador E., Mistry D., Forte G. I., Bravatà V., Minafra L., Calvaruso M., Cammarata F. P., Falk M., Schettino G., Ahire V., Daems N., Boterberg T., Dainiak N., Chaudhary P., Baatout S., Mishra K. P.   +16 more
openaire   +1 more source

Nebulized Lycopene Attenuates Radiation‐Induced Pulmonary Inflammation and Fibrosis in Mice via Activating Nrf2/HO‐1 and Inhibiting TGF‐β1/Smad Signaling

Journal of Food Biochemistry, Volume 2026, Issue 1, 2026.
The development of radiation‐induced lung injury (RILI) presents a major clinical challenge that limits the efficacy and safety of thoracic radiotherapy. This condition evolves from acute inflammatory damage to irreversible fibrotic remodeling, yet effective and targeted treatment options remain scarce.
Zhiming Cui, Hui Zhang, Jiaying Liu, Na Li, Jibo Hu, Yuchao Sun   +5 more
wiley   +1 more source

Rutin Enhances Intestinal Barrier Function and Protects Against X‐Ray Radiation‐Induced Barrier Dysfunction in Human Epithelial Caco‐2 Cells

Molecular Nutrition &Food Research, Volume 69, Issue 22, November 2025.
Rutin enhances intestinal epithelial barrier function by upregulating TJ‐related proteins (ZO‐2, occludin, and claudin‐3), reducing paracellular permeability, and restoring Caco‐2 cell viability impaired by X‐ray radiation. These effects suggest rutin's potential as a natural radioprotective agent for maintaining intestinal barrier integrity under ...
Ha‐Young Park, Jin‐Hee Yu, Soo‐Bin Shin, Young‐Min Kim   +3 more
wiley   +1 more source

Radioprotectors in animal production protection

, 2003
U radu je dat prikaz radioprotektora koji se mogu koristiti u različitim granama stočarske proizvodnje u cilju smanjenja apsorpcije cezijuma-137 u gastrointestinalnom traktu životinja.
Vuković, Dubravka, Mitrović, Radosav, Vićentijević, Mihajlo, Vitorović, Gordana   +3 more
core   +1 more source

Transport processes of radiopharmaceuticals and -modulators

Radiation Oncology, 2011
Radiotherapy and radiology have been indispensable components in cancer care for many years. The detection limit of small tumor foci as well as the development of radio-resistance and severe side effects towards normal tissues led to the development of ...
Langguth Peter, Efferth Thomas
doaj   +1 more source