Results 81 to 90 of about 2,043 (197)

Protective Effects of IMOD and Cimetidine against Radiation-induced Cellular Damage

Journal of Biomedical Physics and Engineering, 2018
Radiation damage is to a large extent caused by overproduction of reactive oxygen species (ROS). Radioprotectors are agents or substances that reduce the effects of radiation in healthy normal tissues while maintaining the sensitivity to radiation damage
Rahgoshai S., Mohammadi M., Refahi S., Oladghaffari M., Aghamiri S. M. R.   +4 more
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Research of beekeeping products using as radioprotectors for plants

Vìsnik Dnìpropetrovsʹkogo Unìversitetu: Serìâ Bìologìâ, Ekologìâ, 2006
Research conducted on a winter wheat, which was cultivated in a 30-km area in the year ofChernobylaccident, allowed to ascertain that complex use of sodium humate and beekeeping products is ineffective for diminishing the negative irradiation influence ...
I. О. Oginova
doaj   +1 more source

Mechanism of Action of Aminothiol Radioprotectors [PDF]

Nature, 1967
How do aminothiols protect living cells from radiation ? One possibility is that they bind to and stabilize those parts of the DNA helix which are not covered by histones. This reduces both primary and secondary damage, and the DNA replication rate is decreased so that repair processes can act before alterations are replicated.
openaire   +2 more sources

Evaluating the radioprotective effect of Cimetidine, IMOD, and hybrid radioprotectors agents: An in-vitro study

, 2021
Introduction: There are various radioprotective agents with different mechanisms that help to decrease ionizing radiation side effects. The radioprotective effect of Cimetidine and IMOD was assessed individually and compared with the hybrid ...
Nader, N. D., Kiapour, M., Aghamiri, M. R., Mehnati, P., Rahgoshai, S., Borujeini, M. H., Banaei, A., Tarighatnia, A., Abedi-Firouzjah, R.   +8 more
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A Review of Clinical Radioprotection and Chemoprotection for Oral Mucositis

Translational Oncology, 2018
The first tenet of medicine, “primum non nocere” or “first, do no harm”, is not always compatible with oncological interventions e.g., chemotherapy, targeted therapy and radiation, since they commonly result in significant toxicities.
Bryan Oronsky, Sharad Goyal, Michelle M. Kim, Pedro Cabrales, Michelle Lybeck, Scott Caroen, Neil Oronsky, Erica Burbano, Corey Carter, Arnold Oronsky   +9 more
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Synthesis of 1,2,5,7-dithiadiazonan-6-ylidenecyanamide. A New Potential Cysteamine Derivate Radioprotector Compound

, 2007
Radioprotectors have been described as a chemical compounds that protect certain normal tissues as opposed to tumors.[...
Italo Menconi, Gerardo Ordónez, Ignacio Martínez, Enrique Angeles, Brígida Camacho, Rafael López-Castañares, Ana María Velázquez, Sandra Díaz-Barriga, Alberto Ramírez   +8 more
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Radioprotectors from pyrodextrins

Chinese Science Bulletin, 2010
Cornstarch heated in the range of 230–280°C depolymerized into pyrodextrins characterized by two-component EPR signals of relatively stable free radicals. These thermally generated radicals could serve as efficient scavengers for free radicals generated from pyrodextrins with the 200 Gy dose of γ-radiation.
Michalski, Oskar, Bidzińska, Ewa, Borowski, Michał, Dyrek, Krystyna, Olko, Paweł, Stolarczyk, Liliana, Swakoń, Jan, Tomasik, Piotr, Wenda, Elżbieta   +8 more
openaire   +2 more sources

Mitogen-like Cerium-Based Nanoparticles Protect Schmidtea mediterranea against Severe Doses of X-rays

, 2023
Novel radioprotectors are strongly demanded due to their numerous applications in radiobiology and biomedicine, e.g., for facilitating the remedy after cancer radiotherapy.
Ermakov, Artem M., Kristina O. Filippova, Shcherbakov, Alexander B., Anton L. Popov, Alexander E. Baranchikov, Alexander B. Shcherbakov, Blagodatsky, Artem S., Popov, Anton L., Artem M. Ermakov, Ermakova, Olga N., Baranchikov, Alexander E., Vladimir K. Ivanov, Nikita N. Chukavin, Artem S. Blagodatsky, Ivanov, Vladimir K., Olga N. Ermakova, Chukavin, Nikita N., Filippova, Kristina O.   +17 more
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Evaluation of new thiadiazoles and benzothiazoles as potential radioprotectors : Free radical scavenging activity in vitro and theoretical studies (QSAR, DFT)

, 2009
International audienceThiol and aminothiol compounds are among the most efficient chemical radioprotectors. To increase their efficiency, we synthesized two new classes of thiol and aminothiol compounds derived from benzothiazole (T1, T2, AM1, AM2) and ...
Vicendo, Patricia, Rima, Ghassoub, Prouillac, Caroline, Poteau, Romuald, Garrigues, Jean-Christophe   +4 more
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Action of Carnosic Acid Against Melanoma: A Strategy for Selective Radiosensitization with Protection of Non-Tumoral Cells

Current Issues in Molecular Biology
Carnosic acid (CA) is a phenolic diterpene with high antioxidant activity that supports its radioprotective capacity. This study aims to determine whether the radiosensitizing effect of CA established in B16F10 melanoma cells also occurs in other melanin-
Amparo Olivares, Isabel de la Fuente, Daniel Gyingiri Achel, Ana María Mercado, José Antonio Garcia-Gamuz, María del Rosario Tudela, Miguel Alcaraz   +6 more
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