Results 31 to 40 of about 915,551 (289)
Activation and Role of Astrocytes in Ischemic Stroke
Frontiers in Cellular Neuroscience, 2021 Ischemic stroke refers to the disorder of blood supply of local brain tissue caused by various reasons. It has high morbidity and mortality worldwide. Astrocytes are the most abundant glial cells in the central nervous system (CNS).
Xin-Ya Shen +5 more
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Hypergravity Attenuates Reactivity in Primary Murine Astrocytes [PDF]
Biomedicines, 2022 Neuronal activity is the key modulator of nearly every aspect of behavior, affecting cognition, learning, and memory as well as motion. Hence, disturbances of the transmission of synaptic signals are the main cause of many neurological disorders. Lesions to nervous tissues are associated with phenotypic changes mediated by astrocytes becoming reactive.
Yannick Lichterfeld +8 more
openaire +5 more sources
Environmental cues determine the fate of astrocytes after spinal cord injury
Neural Regeneration Research, 2017 Reactive astrogliosis occurs after central nervous system (CNS) injuries whereby resident astrocytes form rapid responses along a graded continuum. Following CNS lesions, naïve astrocytes are converted into reactive astrocytes and eventually into scar ...
Fatima M Nathan, Shuxin Li
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Astrocytic Calcium Dynamics Along the Pain Pathway
Frontiers in Cellular Neuroscience, 2020 Astrocytes, once thought to be passive cells merely filling the space between neurons in the nervous system, are receiving attention as active modulators of the brain and spinal cord physiology by providing nutrients, maintaining homeostasis, and ...
Jeiwon Cho, Yeowool Huh, Yeowool Huh
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Reversible reactivity by optic nerve astrocytes [PDF]
Glia, 2013 Reactive astrocytes are typically studied in models that cause irreversible mechanical damage to axons, neuronal cell bodies, and glia. Here, we evaluated the response of astrocytes in the optic nerve head to a subtle injury induced by a brief, mild elevation of the intraocular pressure.
Daniel, Sun, Juan, Qu, Tatjana C, Jakobs
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Astrocytic pathology in Alpers’ syndrome
Acta Neuropathologica Communications, 2023 Refractory epilepsy is the main neurological manifestation of Alpers’ syndrome, a severe childhood-onset mitochondrial disease caused by bi-allelic pathogenic variants in the mitochondrial DNA (mtDNA) polymerase gamma gene (POLG).
Laura A Smith +5 more
doaj +1 more source
Frontiers in Molecular Neuroscience, 2022 Astrocytes respond to injury, infection, and inflammation in the central nervous system by acquiring reactive states in which they may become dysfunctional and contribute to disease pathology. A sub-state of reactive astrocytes induced by proinflammatory
David Labib +18 more
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Astrocytes-hNS1 are a pure culture of human astrocytes.
, 2023 hNS-1 cells were differentiated for 21 days. The differentiated cells were harvested and seeded in culture labware without poly-L-lysine treatment and with DMEM.
Edson Iván Rubio-Hernández (14856891) +5 more
core +1 more source
On the reactive states of astrocytes in prion diseases [PDF]
Prion, 2021 Transformation of astrocytes into reactive states is considered one of the major pathological hallmarks of prion and other neurodegenerative diseases. Recent years witnessed a growing appreciation of the view that reactive astrocytes are intimately involved in chronic neurodegeneration; however, little is known about their role in disease pathogenesis.
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FGF/heparin differentially regulates Schwann cell and olfactory ensheathing cell interactions with astrocytes: a role in astrocytosis [PDF]
, 2007 After injury, the CNS undergoes an astrocyte stress response characterized by reactive astrocytosis/proliferation, boundary formation, and increased glial fibrillary acidic protein (GFAP) and chondroitin sulfate proteoglycan (CSPG) expression. Previously,
Fairless, R. +15 more
core +1 more source