Results 161 to 170 of about 12,430 (191)
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Psychopharmacology, 2005
Associative learning during Pavlovian eyeblink conditioning has been shown to be regulated by 5-HT2A receptors. The existence of inverse agonists that retard learning through an action at the 5-HT2A receptor suggests the existence of constitutive activity at that receptor and that depletion of serotonin should have minimal effects on learning.We ...
A G, Romano +7 more
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Associative learning during Pavlovian eyeblink conditioning has been shown to be regulated by 5-HT2A receptors. The existence of inverse agonists that retard learning through an action at the 5-HT2A receptor suggests the existence of constitutive activity at that receptor and that depletion of serotonin should have minimal effects on learning.We ...
A G, Romano +7 more
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Neuroscience & Biobehavioral Reviews, 2016
Executive function entails the interplay of a group of cognitive processes enabling the individual to anticipate consequences, attain self-control, and undertake appropriate goal-directed behaviour. Serotonin signalling at serotonin 2A receptors (5-HT2AR) has important effects on these behavioural and cognitive pathways, with the prefrontal cortex (PFC)
Susana, Aznar, Mona El-Sayed, Hervig
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Executive function entails the interplay of a group of cognitive processes enabling the individual to anticipate consequences, attain self-control, and undertake appropriate goal-directed behaviour. Serotonin signalling at serotonin 2A receptors (5-HT2AR) has important effects on these behavioural and cognitive pathways, with the prefrontal cortex (PFC)
Susana, Aznar, Mona El-Sayed, Hervig
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Binding Interactions of Psilocin and Serotonin in the 5-HT2A Receptor
2020This report is a learning artifact from the Spring 2020 semester of the UH-4504 Honors Topics in Discovery and Innovation Studios course titled Drug Discovery and Design in the Digital Age. This report should not be used or interpreted as a peer reviewed paper.
Barnes, Katie, Lewis, Stephanie N.
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Functional Selectivity in Serotonin Receptor 2A (5-HT2A) Endocytosis, Recycling, and Phosphorylation
Molecular Pharmacology, 2013G protein-coupled receptor (GPCR) signaling is modulated by endocytosis and endosomal sorting of receptors between degradation and recycling. Differential regulation of these processes by endogenous ligands and synthetic drugs is a poorly understood area of GPCR signaling.
Ishier, Raote +2 more
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No evidence for interaction between 5-HT2A receptor and serotonin transporter genes in schizophrenia
Neuroscience Research, 2005This study was to aim at investigating the potential interaction for the serotonin receptor gene (5-HTR) 2A and serotonin transporter gene (5-HTTLPR) polymorphisms in the development of schizophrenia, as well as the interaction of the two polymorphisms in relation with symptomatology, family history, age of onset and antipsychotic response. Genomic DNA
Pae C. U. +8 more
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Psychopharmacology, 2004
Contradictory evidence exists regarding the role of the 5-HT(2A) receptor (5-HT(2A)R) in hyperactivity and hyperthermia elicited by the substituted amphetamine (+)-3,4-methylenedioxymethamphetamine.The present studies examined the ability of the selective 5-HT(2A)R antagonist M100907 to block hyperactivity and hyperthermia produced across the (+)-MDMA ...
David V, Herin +4 more
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Contradictory evidence exists regarding the role of the 5-HT(2A) receptor (5-HT(2A)R) in hyperactivity and hyperthermia elicited by the substituted amphetamine (+)-3,4-methylenedioxymethamphetamine.The present studies examined the ability of the selective 5-HT(2A)R antagonist M100907 to block hyperactivity and hyperthermia produced across the (+)-MDMA ...
David V, Herin +4 more
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Serotonin 5-HT2A receptors in schizophrenia: Reflexions on an unfinished story
European Neuropsychopharmacology, 2023J. Javier Meana, Javier González-Maeso
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5-HT2A serotonin receptors in the brain of rats and mice hereditarily predisposed to catalepsy
Pharmacology Biochemistry and Behavior, 1995Specific binding of [3H]ketanserin to 5-HT2A serotonin receptor sites in the corpus striatum and frontal cortex and the effect of 5-HT2A antagonists in rats and mice hereditarily predisposed to catalepsy has been studied. Cyproheptadine inhibited the expression of inherited catalepsy in rats and mice, whereas more selective 5-HT2A antagonists ...
A V, Kulikov +4 more
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Dieting and weight loss do not affect on the platelet serotonin 5-HT2A receptor
European Neuropsychopharmacology, 2004Alterations related to the serotonin 5-HT(2A) receptor have been reported in various psychiatric disorders, and the 5-HT(2A) receptor is also one of the receptors mediating the effects of serotonin on feeding and satiety. The present study was carried out in order to investigate the association between the serotonin 5-HT(2A) receptor and weight loss ...
Ingegerd, Rahm +2 more
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Serotonin 5-HT2A receptors are expressed on pyramidal cells and interneurons in the rat cortex
Synapse, 1997The distribution of 5-HT2A receptors in rat cortex was evaluated using newly developed antibodies. Each of three antibodies tested identified an identical pattern of 5-HT2A-like immunoreactivity (5-HT2A-li) in rat cortex with 5-HT2A-li showing a widespread distribution. The majority of 5-HT2A-li cells displayed a pyramidal morphology. While a minority,
D L, Willins, A Y, Deutch, B L, Roth
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