Results 51 to 60 of about 19,892 (167)

Influence of Simvastatin and Interleukin 1 Receptor Antagonist on Expression of Aryl Hydrocarbon Receptors Under Experimental Acute Ileitis

Gastroenterologìa, 2015
Aryl hydrocarbon receptor (AhR) — transcription factor activated by a large number of environmental agents, and may play a role in the pathogenesis of inflammatory bowel diseases in humans and mouse models.
O.S. Zherebiatiev, O.M. Kamyshnyi
doaj   +1 more source

Checkpoint Receptor TIGIT Expressed on Tim-1+ B Cells Regulates Tissue Inflammation

Cell Reports, 2020
Summary: Tim-1, a phosphatidylserine receptor expressed on B cells, induces interleukin 10 (IL-10) production by sensing apoptotic cells. Here we show that mice with B cell-specific Tim-1 deletion develop tissue inflammation in multiple organs including ...
Sheng Xiao, Lloyd Bod, Nathalie Pochet, Savithri Balasubramanian Kota, Dan Hu, Asaf Madi, Jessica Kilpatrick, Jingwen Shi, Allen Ho, Huiyuan Zhang, Raymond Sobel, Howard L. Weiner, Terry B. Strom, Francisco J. Quintana, Nicole Joller, Vijay K. Kuchroo   +15 more
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Programming the tumor microenvironment through microbiome-driven mechanisms

Frontiers in Cellular and Infection Microbiology
The tumor microenvironment (TME) comprises interacting immune, stromal, and metabolic compartments that determine tumor behavior and treatment response.
Jhommara Bautista, Sebastián Calderón-Cevallos, Ana María Salvador-Baquero, Xavier Naranjo-Castillo, Andrés López-Cortés   +4 more
doaj   +1 more source

Polychlorinated naphthalenes in the serum of individuals with thyroid dysfunction and their potential mechanisms of impact on disease progression

Emerging Contaminants
Polychlorinated naphthalenes (PCNs) comprise 75 congeners, with varying concentrations and major congeners across different populations. Recent studies have found a relationship between PCNs and thyroid hormone levels, suggesting they may interfere with ...
Yuhao Fan, Dan Chen, Xinyu Lou, Ye Wu, Jie Sun, Zhiyan Liu, Jun Jin, Tan Chen   +7 more
doaj   +1 more source

Gut microbiome-derived indole-3-carboxaldehyde regulates stress vulnerability in chronic restraint stress by activating aryl hydrocarbon receptors

Pharmacological Research
Chronic stress constitutes a major precipitating factor for Major Depressive Disorder (MDD), and comprehending individual differences in stress responses is crucial for the development of effective intervention strategies for MDD. Recent studies indicate
Congcong Chen, Qiang Xiao, Zhaoyi Wen, Fenfang Gong, Huang Zhan, Jian Liu, Hui Li, Yukun Jiao   +7 more
doaj   +1 more source

Gene-environment interactions in male reproductive health: special reference to the aryl hydrocarbon receptor signaling pathway

Asian Journal of Andrology, 2014
Over the last few decades, there have been numerous reports of adverse effects on the reproductive health of wildlife and laboratory animals caused by exposure to endocrine disrupting chemicals (EDCs).
Leon J S Brokken, Yvonne Lundberg Giwercman   +1 more
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Insulin/insulin like growth factors in cancer: new roles for the aryl hydrocarbon receptor, tumor resistance mechanisms and new blocking strategies

Frontiers in Endocrinology, 2015
The insulin-like growth factor 1 receptor (IGF1R) and the insulin receptor (IR) are receptor tyrosine kinases (RTKs) that are expressed in cancer cells. The results of different studies indicate that tumor proliferation and survival is dependent on the ...
Travis B Salisbury, Justin K Tomblin
doaj   +1 more source

Aryl hydrocarbon receptor-regulated long non-coding RNAs: implications for glycolipid metabolism and prognosis in hepatocellular carcinoma

Frontiers in Oncology
BackgroundHepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths with limited treatment options. Tumor metabolic disorder is elevated in HCC and activates the aryl hydrocarbon receptor (AHR), a transcription factor implicated in ...
Xiaoli Xiao, Yao Liu, Xiaoyong Qu, Logen Liu, Guo-Qing Li, Honghui Chen, Linlin Zhou, Yanping Liu   +7 more
doaj   +1 more source

aryl hydrocarbon receptor

Citation: 'aryl hydrocarbon receptor' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.10432 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for
openaire   +1 more source

Aryl Hydrocarbon Receptor in Health and Disease

MedComm
ABSTRACT The aryl hydrocarbon receptor (AhR) functions as a ligand‐dependent transcription factor, serving as a pivotal environmental sensor that significantly influences both physiological and pathological processes. The inactivated state of AhR is present in the cell cytoplasm and transfer into the nucleus upon activation by a ...
Haonan Li, Yufeng Fan, Jizheng Liu, Shumin Dong, Bin Wen, Yunfei Zhang, Xiaocui Wang, Xuemei Duan, Ying Hu, Ze Yan, Huifeng Shang, Yukai Jing   +11 more
openaire   +2 more sources