Results 61 to 70 of about 19,892 (167)

The role of indole metabolites derived from gut microbiota in Parkinson's disease: A comprehensive review

open access: yesBrain Research Bulletin
Emerging evidence suggests that Parkinson’s disease (PD) extends beyond the brain and involves early disturbances along the gut-brain axis. Among the metabolites shaping this communication, bacterial products derived from tryptophan, particularly indole ...
Shuo Meng
doaj   +1 more source

The Pharmacological Evidences for the Involvement of AhR and GPR35 Receptors in Kynurenic Acid-Mediated Cytokine and Chemokine Secretion by THP-1-Derived Macrophages

open access: yesMolecules
Kynurenic acid (KYNA), a tryptophan metabolite, possesses immunomodulatory properties, although the molecular mechanism of this action has not yet been resolved.
Katarzyna Sawa-Wejksza   +2 more
doaj   +1 more source

The gut–bone axis: mechanisms through which oleic acid regulates bone metabolism and its potential in preventing and treating osteoporosis

open access: yesFrontiers in Nutrition
Osteoporosis is a prevalent metabolic bone disorder characterized by reduced bone mass and increased fracture risk, posing a growing global health burden.
Minshun Zhu   +4 more
doaj   +1 more source

Research progress on mechanisms of postbiotics in regulating gut microecology and immune function in livestock and poultry

open access: yesSiliao yanjiu
Postbiotics, as preparations of inactivated microorganisms and their components, offer advantages such as excellent stability and high safety. They do not rely on the survival of live bacteria but instead, through various active components such as ...
LIU Qiujin   +5 more
doaj  

Aryl hydrocarbon receptor-mediated transcriptional regulation of HSP70 exacerbates endoplasmic reticulum stress in lupus nephritis

open access: yesCell & Bioscience
Lupus nephritis (LN) is a severe and prevalent complication of systemic lupus erythematosus (SLE), often leading to progressive kidney damage. Endoplasmic reticulum (ER) stress, arising from proteostatic imbalance, triggers the unfolded protein response (
Min Wen   +13 more
doaj   +1 more source

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