Results 121 to 130 of about 9,646 (180)

From Vascular Dysfunction to Atherothrombosis: The Pivotal Role of Eicosanoids and Their Receptors in Platelet and Endothelial Imbalance: A Scoping Review. [PDF]

Int J Mol Sci
Ritorto G, Ussia S, Macrì R, Serra M, Tavernese A, Altomare C, Dardano DM, Idone C, Palma E, Muscoli C, Volterrani M, Barillà F, Mollace V, Mollace R.   +13 more
europepmc   +1 more source

Dynamin 2-mediated endocytosis of BLT1 is required for IL-8 production in HMC-1 cells induced by Trichomonas vaginalis-derived secretory products. [PDF]

Parasites Hosts Dis
Lee YA, Shin MH.
europepmc   +1 more source

Tumoral ALOX5 mediated arachidonic acid metabolism regulates immune response in non-small cell lung cancer. [PDF]

Cell Oncol (Dordr)
Gao Y, Xia Y, Li J, Lai Y, Yin S, Lin J, Yu D, Huang S, Lu F, Wang W, Chu Q.   +10 more
europepmc   +1 more source

Differential Metabolites Before and After Allergen Specific Immunotherapy in Children with Allergic Asthma. [PDF]

J Asthma Allergy
Yue Y, Sang M, Zhang S, Hu S, Zhang Y, Zhang S.   +5 more
europepmc   +1 more source

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Leukotriene B4 receptors

Prostaglandins & Other Lipid Mediators, 2002
Leukotriene B4 (LTB4) is a potent chemotactic agent and activating factor for granulocytes. Two cell surface receptors for LTB4 (BLT1 and BLT2) have been isolated in the last few years. These receptors are G-protein-coupled receptors (GPCR), and they have 45% amino acid identity. BLT1 and BLT2 are high- and low- affinity receptors, respectively.
Akiko, Toda, Takehiko, Yokomizo, Takao, Shimizu   +2 more
openaire   +2 more sources

Leukotriene B3, leukotriene B4 and leukotriene B5; Binding to leukotriene B4 receptors on rat and human leukocyte membranes

Prostaglandins, 1986
Specific high-affinity binding sites for [3H]-leukotriene B4 have been identified on membrane preparations from rat and human leukocytes. The rat and human leukocyte membrane preparations show linearity of binding with increasing protein concentration, saturable binding and rapid dissociation of binding by excess unlabelled leukotriene B4. Dissociation
S, Charleson, J F, Evans, R J, Zamboni, Y, Leblanc, B J, Fitzsimmons, C, Leveillé, P, Dupuis, A W, Ford-Hutchinson   +7 more
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Assay for the leukotriene B4 receptor

1987
Publisher Summary This chapter discusses the binding assay in intact cells, membranes, and a detergent-solubilized preparation and a facile neutrophil aggregation assay that can be used to correlate binding data with biological information. The leukotrienes are metabolites of arachidonic acid whose potent biological activities suggest an important ...
R R, Gorman, A H, Lin
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Leukotriene B4 Receptors

2015
Leukotriene B4 (LTB4) is a classical pro-inflammatory lipid mediator that activates and recruits neutrophils into inflammatory areas. LTB4 is an arachidonic acid-derived metabolite produced by 5-lipoxygenase and LTA4 hydrolase. To date, two leukotriene B4 receptors, the high-affinity receptor BLT1 and the low-affinity receptor BLT2, have been cloned ...
Tomoaki Koga, Takehiko Yokomizo
openaire   +1 more source

Leukotriene B4 Receptor: Cloning and Intracellular Signaling

American Journal of Respiratory and Critical Care Medicine, 2000
Leukotriene B 4 (LTB 4 ) is a potent chemotactic compound that is synthesized from arachidonic acid, by the action of 5-lipoxygenase and leukotriene A 4 hydrolase (1-3). While 5-lipoxygenase is present to a limited extent in leukocytes (4), LTA 4 hydrolase is present ubiquitously in many tissues including the lung, kidney, spleen, and ...
T, Yokomizo, K, Masuda, K, Kato, A, Toda, T, Izumi, T, Shimizu   +5 more
openaire   +2 more sources