Results 81 to 90 of about 8,520 (182)
Glia, Volume 73, Issue 8, Page 1642-1659, August 2025.Main Points AQP4ex and OAP‐forming AQP4M23 are expressed in non‐neuronal cells of the olfactory epithelium. AQP4ex‐KO and OAP‐null mice show reduced cell density, including OSNs, and impaired odor responses and behavior, with AQP4ex emerging as key regulator.
Donatella Lobraico +8 more
wiley +1 more source
Functions of Purinergic Receptors [PDF]
, 2019 Purinergic receptors, also known as purinoceptors, are a family of plasma membrane molecules found in many mammalian tissues. Purinergic receptors are transmembrane receptors consisting of two main categories.
Sarikaya, Eren
core +2 more sources
British Journal of Pharmacology, Volume 182, Issue 16, Page 3800-3817, August 2025.Background and Purpose Nimodipine, an L‐type voltage‐gated calcium channel blocker, is an approved cerebral vasorelaxant. We hypothesized that nimodipine attenuates the pro‐inflammatory shift in microglial phenotypes. Here, we analysed the effects of nimodipine on morphological and functional microglial phenotypes as well as their transcriptomic ...
István Pesti +10 more
wiley +1 more source
Frontiers in Cellular Neuroscience, 2019 Exploration of purinergic signaling in brainstem homeostatic control processes is challenging the traditional view that the biphasic hypoxic ventilatory response, which comprises a rapid initial increase in breathing followed by a slower secondary ...
Robert J. Reklow +13 more
doaj +1 more source
In vitro functional properties of the rat bladder regenerated by the bladder acellular matrix graft. [PDF]
, 1998 PurposeTo assess the response of rat urinary bladder regenerated by the homologous bladder acellular matrix graft (BAMG) to in vitro electrical and pharmacologic stimuli.Materials and methodsIn Sprague-Dawley rats, partial cystectomy (>50%) was ...
Dahiya, R +5 more
core +1 more source
On the origin of spontaneous activity in the bladder [PDF]
, 2015 ObjectivesTo characterise separately the pharmacological profiles of spontaneous contractions from the mucosa and detrusor layers of the bladder wall and to describe the relationship in mucosa between ATP release and spontaneous contractions.Materials ...
Fry, Chris H, Kushida, N
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Dual role for pannexin 1 at synapses: regulating functional and morphological plasticity
The Journal of Physiology, Volume 603, Issue 15, Page 4237-4253, 1 August 2025.Abstract figure legend Pannexin 1 (PANX1) regulation of dendritic spines. The postnatal decrease in PANX1 expression could release key spine cytoskeleton‐regulating proteins enabling spine stabilization. Does the physiological decrease in neuronal PANX1 levels across brain development underlie dendritic spine maturation?
Adriana Casillas Martinez +3 more
wiley +1 more source
Frontiers in Immunology, 2017 Cancer is still one of the world’s most pressing health-care challenges, leading to a high number of deaths worldwide. Immunotherapy is a new developing therapy that boosts patient’s immune system to fight cancer by modifying tumor–immune cells ...
Paola de Andrade Mello +2 more
doaj +1 more source
ATP Mediates Pyroptosis in the Intestinal Mucosal System During Colitis
Journal of Cellular Physiology, Volume 240, Issue 7, July 2025.ABSTRACT Damage‐associated molecular patterns (DAMPs) are molecules released from damaged or dying cells that contribute to inflammation and cell death. Extracellular ATP, a type of DAMP, has been studied primarily in the context of pyroptosis in monocytes.
Sihyun Jeong +6 more
wiley +1 more source
Short- and long-term (trophic) purinergic signalling [PDF]
, 2016 There is long-term (trophic) purinergic signalling involving cell proliferation, differentiation, motility and death in the development and regeneration of most systems of the body, in addition to fast purinergic signalling in neurotransmission ...
Burnstock, G
core +1 more source