Results 81 to 90 of about 13,842 (161)
The Journal of Physiology, Volume 604, Issue 1, Page 379-394, 1 January 2026.Abstract figure legend Detrusor smooth muscle surrounding the urinary bladder produces transient pressure events essential for sensing bladder fullness during the filling phase. We investigated the role of adenosine, a ubiquitous signalling molecule, in regulating bladder smooth muscle function.
Gerald M. Herrera +8 more
wiley +1 more source
P2X7 Receptor Mediated Increase In Cell Membrane Permeability
Ankara Üniversitesi Tıp Fakültesi Mecmuası, 2018 Purinergic receptors consist of two main families; P2X and P2Y. P2Y receptors are G protein coupled receptors (GPCR), whereas P2X receptors are non-selective cation channels. P2X7 receptors which is a member of P2X receptors, have been found myriad types
Șerife Cankurtaran-Sayar, Kemal Sayar
doaj +1 more source
Purinergic signalling: past, present and future [PDF]
, 2009 The discovery of non-adrenergic, non-cholinergic neurotransmission in the gut and bladder in the early 1960's is described as well as the identification of adenosine 5'-triphosphate (ATP) as a transmitter in these nerves in the early 1970's.
Burnstock, G
core +1 more source
Dinucleoside polyphosphates : newly detected uraemic compounds with an impact on leucocyte oxidative burst [PDF]
, 2009 Background. Dinucleoside polyphosphates (NpnN) have pathophysiologic roles in cardiovascular disease and are newly detected uraemic retention solutes. They were retrieved in human plasma, tissues and cells.
Dhondt, Annemieke +5 more
core +1 more source
Drug-like antagonists of P2Y receptors — from lead identification to drug development [PDF]
, 2016 P2Y receptors are expressed in virtually all cells and tissue types and mediate an astonishing array of biological functions, including platelet aggregation, smooth muscle cell proliferation, and immune regulation.
Conroy, Sean +3 more
core +1 more source
The Concise Guide to PHARMACOLOGY 2025/26: Ion channels
British Journal of Pharmacology, Volume 182, Issue S1, Page S152-S241, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +86 more
wiley +1 more source
BMC Neuroscience, 2007 Background Adrenal chromaffin cells mediate acute responses to stress through the release of epinephrine. Chromaffin cell function is regulated by several receptors, present both in adrenergic (AD) and noradrenergic (NA) cells.
Castro Enrique +3 more
doaj +1 more source
Emerging key roles for P2X receptors in the kidney [PDF]
, 2013 P2X ionotropic non-selective cation channels are expressed throughout the kidney and are activated in a paracrine or autocrine manner following the binding of extracellular ATP and related extracellular nucleotides. Whilst there is a wealth of literature
Birch, R. E. +3 more
core +2 more sources
The Concise Guide to PHARMACOLOGY 2025/26: Enzymes
British Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +31 more
wiley +1 more source
Frontiers in Neuroscience, 2009 Vasoactive intestinal peptide (VIP) immunoreactive secretomotor neurons in the submucous plexus are involved in mediating bacterial toxin-induced hypersecretion leading to diarrhoea.
Jaime Pei Pei Foong, Joel C Bornstein
doaj +1 more source