Results 11 to 20 of about 187,466 (308)
Redox signaling in acute pancreatitis
Redox Biology, 2015 Acute pancreatitis is an inflammatory process of the pancreatic gland that eventually may lead to a severe systemic inflammatory response. A key event in pancreatic damage is the intracellular activation of NF-κB and zymogens, involving also calcium ...
Salvador Pérez +3 more
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Redox signaling in neurodegeneration
Neurobiology of Disease, 2015 D. Allan Butterfield
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Ref-1 redox activity modulates canonical Wnt signaling in endothelial cells
Redox BiologyIschemic retinopathies, including proliferative diabetic retinopathy (PDR) and retinopathy of prematurity (ROP), are characterized by abnormal retinal neovascularization and can lead to blindness in children and adults.
Gabriella D. Hartman +12 more
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Redox signaling in hypertension [PDF]
Cardiovascular Research, 2006 Diseases such as hypertension, atherosclerosis and diabetes are associated with vascular functional and structural changes including endothelial dysfunction, altered contractility and vascular remodeling. Cellular events underlying these processes involve changes in vascular smooth muscle cell (VSMC) growth, apoptosis/anoikis, cell migration ...
Paravicini, Tamara M., Touyz, Rhian M.
openaire +5 more sources
Frontiers in Cardiovascular Medicine, 2023 Assessing regional wall motion abnormalities (RWMA) in the myocardium may provide early diagnosis and treat chronic remodeling in STEMI patients. We assessed RWMA in 217 subjects with anterior STEMI admitted to Era University Hospital in Lucknow, UP ...
S. Mohd. Shiraz Rizvi +6 more
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Oxidative modification of proteins: from damage to catalysis, signaling, and beyond [PDF]
, 2021 Significance: The systematic investigation of oxidative modification of proteins by reactive oxygen species started in 1980. Later, it was shown that reactive nitrogen species could also modify proteins.
Gomes, Fernando +12 more
core +1 more source
Protein Transnitrosylation Signaling Networks Contribute to Inflammaging and Neurodegenerative Disorders [PDF]
, 2021 Significance: Physiological concentrations of nitric oxide (NO•) and related reactive nitrogen species (RNS) mediate multiple signaling pathways in the nervous system.
Lipton, Stuart A +6 more
core +1 more source
Mitochondrial Redox Signaling in O2-Sensing Chemoreceptor Cells
, 2022 Significance: Acute responses to hypoxia are essential for the survival of mammals. The carotid body (CB), the main arterial chemoreceptor, contains glomus cells with oxygen (O2)-sensitive K+ channels, which are inhibited during hypoxia to trigger ...
Gao Chen, Lin +3 more
core +1 more source
Differential regulation of miRNA and mRNA expression in the myocardium of Nrf2 knockout mice
BMC Genomics, 2017 Background Nuclear Factor Erythroid-derived 2-like 2 (Nrf2) senses oxidative environments and/or stress and initiates a cytoprotective response through transcriptional activation of antioxidant and detoxification genes.
Justin M. Quiles +5 more
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Redox Homeostasis in Pancreatic β-Cells: From Development to Failure
Antioxidants, 2021 Redox status is a key determinant in the fate of β-cell. These cells are not primarily detoxifying and thus do not possess extensive antioxidant defense machinery.
Štěpánka Benáková +2 more
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